MULTISPECIES: pyruvate kinase [Enterobacteriaceae].

LOCUS       WP_000091148             480 aa            linear   BCT 19-NOV-2024
ACCESSION   WP_000091148
VERSION     WP_000091148.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 480)
  AUTHORS   Zhong,W., Morgan,H.P., McNae,I.W., Michels,P.A.,
            Fothergill-Gilmore,L.A. and Walkinshaw,M.D.
  TITLE     `In crystallo' substrate binding triggers major domain movements
            and reveals magnesium as a co-activator of Trypanosoma brucei
            pyruvate kinase
  JOURNAL   Acta Crystallogr D Biol Crystallogr 69 (Pt 9), 1768-1779 (2013)
   PUBMED   23999300
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR01064.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..480
                     /gene="pyk"
     Protein         1..480
                     /product="pyruvate kinase"
                     /EC_number="2.7.1.40"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0004743 - pyruvate kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0030955 - potassium ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /calculated_mol_wt=51226
     Region          3..469
                     /region_name="PRK05826"
                     /note="pyruvate kinase; Provisional"
                     /db_xref="CDD:235619"
ORIGIN      
        1 msrrlrrtki vttlgpatdr dnnlekviaa ganvvrmnfs hgspedhkmr adkvreiaak
       61 lgrhvailgd lqgpkirvst fkegkvflni gdkflldanl gkgegdkekv gidykglpad
      121 vvpgdillld dgrvqlkvle vqgmkvftev tvggplsnnk ginklgggls aealtekdka
      181 diktaaligv dylavsfprc gedlnyarrl ardagcdaki vakveraeav csqdamddii
      241 lasdvvmvar gdlgveigdp elvgiqkali rrarqlnrav itatqmmesm itnpmptrae
      301 vmdvanavld gtdavmlsae taagqypset vaamarvclg aekipsinvs khrldvqfdn
      361 veeaiamsam yaanhlkgvt aiitmtesgr talmtsriss glpifamsrh ertlnltaly
      421 rgvtpvhfds andgvaaase avnllrdkgy lmsgdlvivt qgdvmstvgs tnttriltve