MULTISPECIES: betaine-aldehyde dehydrogenase [Enterobacteriaceae].

LOCUS       WP_000089110             490 aa            linear   BCT 16-DEC-2020
ACCESSION   WP_000089110
VERSION     WP_000089110.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF009725.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK13252
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..490
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..490
                     /gene="betB"
     Protein         1..490
                     /product="betaine-aldehyde dehydrogenase"
                     /EC_number="1.2.1.8"
                     /GO_function="GO:0008802 - betaine-aldehyde dehydrogenase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0019285 - glycine betaine biosynthetic
                     process from choline [Evidence IEA]"
                     /calculated_mol_wt=52780
     Region          1..490
                     /region_name="PRK13252"
                     /note="betaine aldehyde dehydrogenase; Provisional"
                     /db_xref="CDD:183918"
     Site            order(64,66,70,73,77,80,114,118,125..129,137,139..141,235,
                     247,269,272,275..276,309,324,422..425,428..429,431,434,
                     436..439,441..442,450,452,456,458,461,463,475..480,
                     482..483)
                     /site_type="other"
                     /note="tetrameric interface [polypeptide binding]"
                     /db_xref="CDD:143409"
     Site            order(149..150,152..153,176,209,227,229..230,233,252..254,
                     286,387,389,453)
                     /site_type="other"
                     /note="NAD binding site [chemical binding]"
                     /db_xref="CDD:143409"
     Site            order(153,252,283,286)
                     /site_type="active"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:143409"
ORIGIN      
        1 msrmaeqqly ihggytsats grtfetinpa ngnvlatvqa agredvdrav ksaqqgqkiw
       61 asmtamersr ilrravdilr erndelakle tldtgkayse tstvdivtga dvleyyagli
      121 palegsqipl retsfvytrr eplgvvagig awnypiqial wksapalaag namifkpsev
      181 tpltalklae iyseaglpdg vfnvlpgvga etgqyltehp giakvsftgg vasgkkvman
      241 saasslkevt melggkspli vfddadldla adiammanff ssgqvctngt rvfvpakcka
      301 afeqkilarv eriragdvfd pqtnfgplvs fphrdnvlry iakgkeegar vlcggdvlkg
      361 dgfdngawva ptvftdcsdd mtivreeifg pvmsiltyes edevirrand tdyglaagiv
      421 tadlnrahrv ihqleagicw intwgespae mpvggykhsg igrengvmtl qsytqvksiq
      481 vemakfqsif