betaine-aldehyde dehydrogenase [Escherichia coli].

LOCUS       WP_000089099             490 aa            linear   BCT 19-JUN-2019
ACCESSION   WP_000089099
VERSION     WP_000089099.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF009725.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK13252
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..490
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..490
                     /gene="betB"
     Protein         1..490
                     /product="betaine-aldehyde dehydrogenase"
                     /EC_number="1.2.1.8"
                     /GO_function="GO:0008802 - betaine-aldehyde dehydrogenase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0019285 - glycine betaine biosynthetic
                     process from choline [Evidence IEA]"
                     /calculated_mol_wt=52746
     Region          1..490
                     /region_name="PRK13252"
                     /note="betaine aldehyde dehydrogenase; Provisional"
                     /db_xref="CDD:183918"
     Site            order(64,66,70,73,77,80,114,118,125..129,137,139..141,235,
                     247,269,272,275..276,309,324,422..425,428..429,431,434,
                     436..439,441..442,450,452,456,458,461,463,475..480,
                     482..483)
                     /site_type="other"
                     /note="tetrameric interface [polypeptide binding]"
                     /db_xref="CDD:143409"
     Site            order(149..150,152..153,176,209,227,229..230,233,252..254,
                     286,387,389,453)
                     /site_type="other"
                     /note="NAD binding site [chemical binding]"
                     /db_xref="CDD:143409"
     Site            order(153,252,283,286)
                     /site_type="active"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:143409"
ORIGIN      
        1 msrmaeqqly ihggytsats grtfetinpa ngnvlatvqa agredvdrav ksaqqgqkiw
       61 aamtamersr ilrravdilr erndelakle tldtgkayse tstvdivtga dvleyyagli
      121 pslegsqipl retsfvytrr eplgvvagig awnypiqial wksapalaag namifkpsev
      181 tpltalklae iyseaglpdg vfnvlpgvga etgqyltehp giakvsftgg vasgkkvman
      241 saasslkevt melggkspli vfddadldla adiammanff ssgqvctngt rvfvpakcna
      301 afeqkilarv eriragdvfd pqtnfgplvs fphrdnvlry iakgkeegar vlcggdvlkg
      361 dgldngawva ptvftdcsde mtivreeifg pvmsiltyes edevirrand tdyglaagiv
      421 tadlnrahrv ihqleagicw intwgespae mpvggykhsg igrengvmtl qsytqvksiq
      481 vemakfqsif