MULTISPECIES: site-specific integrase [Enterobacteriaceae].

LOCUS       WP_000083142             649 aa            linear   BCT 31-MAR-2023
ACCESSION   WP_000083142
VERSION     WP_000083142.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 649)
  AUTHORS   Grainge,I. and Jayaram,M.
  TITLE     The integrase family of recombinase: organization and function of
            the active site
  JOURNAL   Mol Microbiol 33 (3), 449-456 (1999)
   PUBMED   10577069
REFERENCE   2  (residues 1 to 649)
  AUTHORS   Gopaul,D.N. and Duyne,G.D.
  TITLE     Structure and mechanism in site-specific recombination
  JOURNAL   Curr Opin Struct Biol 9 (1), 14-20 (1999)
   PUBMED   10047575
REFERENCE   3  (residues 1 to 649)
  AUTHORS   Esposito,D. and Scocca,J.J.
  TITLE     The integrase family of tyrosine recombinases: evolution of a
            conserved active site domain
  JOURNAL   Nucleic Acids Res 25 (18), 3605-3614 (1997)
   PUBMED   9278480
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10100329
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..649
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     Protein         1..649
                     /product="site-specific integrase"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence
                     IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /calculated_mol_wt=73892
     Region          7..66
                     /region_name="DUF6538"
                     /note="Domain of unknown function (DUF6538); pfam20172"
                     /db_xref="CDD:466323"
     Region          409..603
                     /region_name="INT_C_like_1"
                     /note="Uncharacterized site-specific tyrosine recombinase,
                     C-terminal catalytic domain; cd01184"
                     /db_xref="CDD:271184"
     Site            order(456,564,567..568,601)
                     /site_type="active"
                     /db_xref="CDD:271184"
ORIGIN      
        1 msqryklyrr tsgiyvvris vpqrfrryag qceihtstgt hdlheakqks alllavwyqt
       61 lqeyeqldyr tlsdcaplla gegmislsnf aqsielpisq lirevvnrnl pvfwlatgqf
      121 gfyvdefnav erepgakrek qsddekdqpk eviilnsafe lgiesfangy lrpfnprhtl
      181 dcllsagvse geaafrtsgd nqsggwffdl pgvditadsl liskvhaegl rltwlvkttp
      241 pavsihpavp lvapvianey vhrkhynenl swlreeylkh rrkgkvseaa lrdiryyfdl
      301 mievmgdiql edfdrdflra yesklrtipa nrnlmkgkhg vktldeliak aaecgdklmt
      361 eesvkkying lygamewavd dgkflkspcd nffppddkge reqdhtdife pheikaifsq
      421 pwfvagtver naqgrfhqyc pfhywapllg lmtgarvnei aqlmlddvla ddgvyylnle
      481 sdsengkklk nansrrkipv hstlielgfi eyvdalkaag ydrlfpelkp hktkgygrpv
      541 sawfneslla grlklerdrs ksfhsfrhsv stllkekgvs selrgqllgh vrgktetevr
      601 yskdlkpvhm vevvekidfs lpeiarfnip dgldavrdal rrkrgkqtg