MULTISPECIES: 2-isopropylmalate synthase [Salmonella].

LOCUS       WP_000082819             523 aa            linear   BCT 01-JUN-2019
ACCESSION   WP_000082819
VERSION     WP_000082819.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF002084.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK00915
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..523
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..523
                     /gene="leuA"
     Protein         1..523
                     /product="2-isopropylmalate synthase"
                     /EC_number="2.3.3.13"
                     /GO_function="GO:0003852 - 2-isopropylmalate synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0019752 - carboxylic acid metabolic
                     process [Evidence IEA]"
                     /calculated_mol_wt=57300
     Region          1..512
                     /region_name="PRK00915"
                     /note="2-isopropylmalate synthase; Validated"
                     /db_xref="CDD:234864"
     Site            order(13..14,17,44,75,97,139,141,169,171,202,204)
                     /site_type="active"
                     /db_xref="CDD:163678"
     Site            order(13..14,44)
                     /site_type="active"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:163678"
     Site            order(202,204)
                     /site_type="metal-binding"
                     /note="metal binding site [ion binding]"
                     /db_xref="CDD:163678"
ORIGIN      
        1 msqqviifdt tlrdgeqalq aslsakeklq ialalermgv dvmevgfpvs spgdfesvqt
       61 iartiknsrv calarcvekd idvaaqalkv adafrihtfi atspmhiatk lrstldevie
      121 ravymvkrar nytddvefsc edagrtpvdd larvveaain agartinipd tvgytmpfef
      181 agiisglyer vpnidkaiis vhthddlgia vgnslaavha garqvegamn gigeragnca
      241 leevimaikv rkdimnvhtn inhheiwrts qtvsqicnmp ipankaivgs gafahssgih
      301 qdgvlknren yeimtpesig lnqiqlnlts rsgraavkhr meemgykdtd ynmdhlydaf
      361 lkladkkgqv fdydlealaf inkqqeepeh frldyfsvqs gssdiatasv klacgeeika
      421 eaangngpvd aiyqainrit gydvelvkyd lnakgqgkda lgqvdivvnh hgrrfhgvgl
      481 atdivessak amvhvlnniw raaevekelq rkaqnkennk etv