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MULTISPECIES: bifunctional

FASTAView on NCBI
LOCUS       WP_000080139             355 aa            linear   BCT 17-JAN-2025
            histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB
            [Escherichia].
ACCESSION   WP_000080139
VERSION     WP_000080139.1
KEYWORDS    RefSeq.
SOURCE      Escherichia
  ORGANISM  Escherichia
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF003937.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK05446
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..355
                     /organism="Escherichia"
                     /db_xref="taxon:561"
     gene            1..355
                     /gene="hisB"
     Protein         1..355
                     /product="bifunctional
                     histidinol-phosphatase/imidazoleglycerol-phosphate
                     dehydratase HisB"
                     /EC_number="3.1.3.15"
                     /EC_number="4.2.1.19"
                     /GO_function="GO:0004401 - histidinol-phosphatase activity
                     [Evidence IEA]"
                     /GO_function="GO:0004424 - imidazoleglycerol-phosphate
                     dehydratase activity [Evidence IEA]"
                     /GO_process="GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=40159
     Region          2..355
                     /region_name="PRK05446"
                     /note="bifunctional
                     histidinol-phosphatase/imidazoleglycerol-phosphate
                     dehydratase HisB"
                     /db_xref="CDD:235471"
ORIGIN      
        1 msqkylfidr dgtlisepps dfqvdrfdkl afepgvipql lklqkagykl vmitnqdglg
       61 tqsfpqadfd gphnlmmqif tsqgvqfdev licphlpade cdcrkpkvkl verylaeqam
      121 dransyvigd ratdiqlaen mginglrydr etlnwpmige qltrrdryah vvrntketqi
      181 dvqvwldreg gskintgvgf fdhmldqiat hggfrmeinv kgdlyiddhh tvedtglalg
      241 ealkialgdk rgicrfgfvl pmdeclarca ldisgrphle ykaeftyqrv gdlstemieh
      301 ffrslsytmg vtlhlktkgk ndhhrveslf kafgrtlrqa irvegdtlps skgvl