Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

MULTISPECIES: SIS domain-containing protein [Salmonella].


LOCUS       WP_000075429             353 aa            linear   BCT 21-JUL-2024
ACCESSION   WP_000075429
VERSION     WP_000075429.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 353)
  AUTHORS   Bateman,A.
  TITLE     The SIS domain: a phosphosugar-binding domain
  JOURNAL   Trends Biochem Sci 24 (3), 94-95 (1999)
   PUBMED   10203754
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11454870
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..353
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     Protein         1..353
                     /product="SIS domain-containing protein"
                     /EC_number="3.5.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /calculated_mol_wt=39189
     Region          9..336
                     /region_name="AgaS"
                     /note="Fructoselysine-6-P-deglycase FrlB or related
                     protein, duplicated sugar isomerase (SIS) domain [Cell
                     wall/membrane/envelope biogenesis]; COG2222"
                     /db_xref="CDD:441824"
ORIGIN      
        1 msptmltyin eesdvlanii rrhrqsleev srfasqktlr rililatgss lnaafcaryf
       61 fercgisidi kepytfsqye nsdpqadmvi aisqsgksas tleamrkvqa qgrpvfalta
      121 dpqsplgkas dypldiltgi esvgfvtrgf satvlnllli alliarqqqr ltesqveeyv
      181 aqlqriaatl plvivrteaf ihqhqavlrn gtrfvatgyg alvgvakele tkftetvrvp
      241 ssgfeleaym hgpyleanae hvmfffedrp darsralrey mtpavaktft ltlakaaqdd
      301 qtlaldvavd hhfspllliv pvqlmafhia slkgidlsvr ifddfdrvlk ski