LacI family DNA-binding transcriptional regulator [Escherichia

LOCUS       WP_000075400             332 aa            linear   BCT 22-JUL-2024
            coli].
ACCESSION   WP_000075400
VERSION     WP_000075400.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 332)
  AUTHORS   Fukami-Kobayashi,K., Tateno,Y. and Nishikawa,K.
  TITLE     Parallel evolution of ligand specificity between LacI/GalR family
            repressors and periplasmic sugar-binding proteins
  JOURNAL   Mol Biol Evol 20 (2), 267-277 (2003)
   PUBMED   12598694
REFERENCE   2  (residues 1 to 332)
  AUTHORS   Nguyen,C.C. and Saier,M.H. Jr.
  TITLE     Phylogenetic, structural and functional analyses of the LacI-GalR
            family of bacterial transcription factors
  JOURNAL   FEBS Lett 377 (2), 98-102 (1995)
   PUBMED   8543068
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11446715
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..332
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     Protein         1..332
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription
                     factor activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /calculated_mol_wt=36104
     Region          3..328
                     /region_name="PurR"
                     /note="DNA-binding transcriptional regulator, LacI/PurR
                     family [Transcription]; COG1609"
                     /db_xref="CDD:441217"
ORIGIN      
        1 msptiydiar vagvskstvs rvlnkqtnis pearekvlra ieelqyqpnk laraltssgf
       61 daimvistrs tkttagnpff sevlhaitak aeeegfdvil qtshtpaedl qkceskikqk
      121 mikgiimlss padesffaql dkydipvvvi gkvegqyahv ysvdtdnfgd sialtdalie
      181 sghqniaclh apldvhvsvd rvngykqsle dhniavrdew ivdggythet alqaarqlls
      241 qsplpeavfa tdslklmsiy raaaekniai pqqlavvgys netlsfiltp apggidvptq
      301 elgrqscell frliagkpsp qnitvathmt lk