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MULTISPECIES: LacI family DNA-binding transcriptional regulator


LOCUS       WP_000075383             332 aa            linear   BCT 22-JUL-2024
            [Enterobacteriaceae].
ACCESSION   WP_000075383
VERSION     WP_000075383.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 332)
  AUTHORS   Fukami-Kobayashi,K., Tateno,Y. and Nishikawa,K.
  TITLE     Parallel evolution of ligand specificity between LacI/GalR family
            repressors and periplasmic sugar-binding proteins
  JOURNAL   Mol Biol Evol 20 (2), 267-277 (2003)
   PUBMED   12598694
REFERENCE   2  (residues 1 to 332)
  AUTHORS   Nguyen,C.C. and Saier,M.H. Jr.
  TITLE     Phylogenetic, structural and functional analyses of the LacI-GalR
            family of bacterial transcription factors
  JOURNAL   FEBS Lett 377 (2), 98-102 (1995)
   PUBMED   8543068
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11446715
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..332
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     Protein         1..332
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription
                     factor activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /calculated_mol_wt=36018
     Region          3..328
                     /region_name="PurR"
                     /note="DNA-binding transcriptional regulator, LacI/PurR
                     family [Transcription]; COG1609"
                     /db_xref="CDD:441217"
ORIGIN      
        1 msptiydiar vagvskstvs rvlnkqtnis pearekvlra ieelqyqpnk laraltssgf
       61 daimvistrs tkttagnpff sevlhaitak aeeegfdvil qtshnpaedl qkceskikqk
      121 mikgiimlss padesffaql dkydipvvvi gkvegqyahv ysvdtdnfgd sialtdalie
      181 sghqniaclh apldvhvsvd rvngykqsls ahniavrdkw ivdggythet alqaarqlls
      241 qsplpeavfa tdslklmsiy raaaekniai pqqlavvgys netlsfiltp apggidvptq
      301 elgqqscell frlisgkpsp qnitvathmt lk