MULTISPECIES: SDR family oxidoreductase [Salmonella].

LOCUS       WP_000069000             477 aa            linear   BCT 21-JUL-2024
ACCESSION   WP_000069000
VERSION     WP_000069000.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 477)
  AUTHORS   Persson,B., Kallberg,Y., Bray,J.E., Bruford,E., Dellaporta,S.L.,
            Favia,A.D., Duarte,R.G., Jornvall,H., Kavanagh,K.L., Kedishvili,N.,
            Kisiela,M., Maser,E., Mindnich,R., Orchard,S., Penning,T.M.,
            Thornton,J.M., Adamski,J. and Oppermann,U.
  TITLE     The SDR (short-chain dehydrogenase/reductase and related enzymes)
            nomenclature initiative
  JOURNAL   Chem Biol Interact 178 (1-3), 94-98 (2009)
   PUBMED   19027726
REFERENCE   2  (residues 1 to 477)
  AUTHORS   Kavanagh,K.L., Jornvall,H., Persson,B. and Oppermann,U.
  TITLE     Medium- and short-chain dehydrogenase/reductase gene and protein
            families : the SDR superfamily: functional and structural diversity
            within a family of metabolic and regulatory enzymes
  JOURNAL   Cell Mol Life Sci 65 (24), 3895-3906 (2008)
   PUBMED   19011750
REFERENCE   3  (residues 1 to 477)
  AUTHORS   Oppermann,U., Filling,C., Hult,M., Shafqat,N., Wu,X., Lindh,M.,
            Shafqat,J., Nordling,E., Kallberg,Y., Persson,B. and Jornvall,H.
  TITLE     Short-chain dehydrogenases/reductases (SDR): the 2002 update
  JOURNAL   Chem Biol Interact 143-144, 247-253 (2003)
   PUBMED   12604210
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10142831
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     Protein         1..477
                     /product="SDR family oxidoreductase"
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /calculated_mol_wt=53864
     Region          5..296
                     /region_name="SDR_a2"
                     /note="atypical (a) SDRs, subgroup 2; cd05245"
                     /db_xref="CDD:187556"
     Site            order(9,11..12,14,33..35,73..75,109..111,122,126,145..148)
                     /site_type="other"
                     /note="putative NAD(P) binding site [chemical binding]"
                     /db_xref="CDD:187556"
     Site            order(122,126)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:187556"
     Region          330..463
                     /region_name="DUF2867"
                     /note="Protein of unknown function (DUF2867); pfam11066"
                     /db_xref="CDD:431633"
ORIGIN      
        1 maqrilvlga sgyigqhlvf alsqqghqvr aaarrierle kqrlanvsch kvdlhwpenl
       61 pallrdidtv yylvhgmgeg gdfiaherqa alnvrdalrq tpvkqlifls slqapaheqs
      121 dhlrarqlta dtlrdagvpv telragiivg agsaafevmr dmvynlpilt pprwvrsrtt
      181 pialenllyy lvglldhpar ehrileaagp qvlsyqqqfe rfmavsgkrr plipvpfptr
      241 wisvwflnvi tsvppttaka liqglrhdll addaalkkli pqtlitfdda vrrtlkeeek
      301 lvnssdwgyd alafarwrpe ygyfpkqagf taqtpaslsa lwqvvnrlgg kegyffgnil
      361 wqtraamdrl vghklakgrp shtllkpgdt vdswkviive pekqltllfg mkapglgrls
      421 ftlhdkgryr eidvrawwhp hgmpgliywl lmipahlfif rgmarriarl aeqitek