MULTISPECIES: MFS transporter [Salmonella].

LOCUS       WP_000061259             420 aa            linear   BCT 01-JAN-2025
ACCESSION   WP_000061259
VERSION     WP_000061259.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 420)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 420)
  AUTHORS   Zhang,X.C., Zhao,Y., Heng,J. and Jiang,D.
  TITLE     Energy coupling mechanisms of MFS transporters
  JOURNAL   Protein Sci 24 (10), 1560-1579 (2015)
   PUBMED   26234418
REFERENCE   3  (residues 1 to 420)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13022908
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     Protein         1..420
                     /product="MFS transporter"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=46006
     Region          13..415
                     /region_name="MFS_ExuT_GudP_like"
                     /note="Hexuronate transporter, Glucarate transporter, and
                     similar transporters of the Major Facilitator Superfamily;
                     cd17319"
                     /db_xref="CDD:340877"
     Site            order(27..28,31..32,35,71,121..122,124..126,129,149,
                     152..153,156,247,250..251,254..256,259,287,291,341..342,
                     346,350,366,369..370,373..374,377)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340877"
ORIGIN      
        1 msmaltappt rkrflivacl figifiayld rvnvsvlaan epflaymgie gmplqigmmm
       61 tvflaaygia nvvlsplgdy lgprkammlc iliwtialmi ggvatsfali iicrillgig
      121 egfyyplqsv fiknwfpkqe rgranaawiv gqsvapaiam pfftwwigth gwrsnfflca
      181 algliplwll wryvadkpeq hksiseqela yikagqetes agssesfmlr vkpvitnysy
      241 wllvlwylcl qclywgmitw lptylksarg fswaemgwla slpfvlsifa kaaagvfvdk
      301 igrsapilmv lmffagvsiy fgtitehkym savllsfava fctmgtpvaw tllqgmipgk
      361 sisaasgvmn gvanglssls pvfiglfisi tgtytggllc lvfisaiavv saliltikky