glutarate dioxygenase GlaH [Shigella flexneri].

LOCUS       WP_000054294             345 aa            linear   BCT 30-MAY-2022
ACCESSION   WP_000054294
VERSION     WP_000054294.1
KEYWORDS    RefSeq.
SOURCE      Shigella flexneri
  ORGANISM  Shigella flexneri
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Shigella.
REFERENCE   1  (residues 1 to 345)
  AUTHORS   Knorr,S., Sinn,M., Galetskiy,D., Williams,R.M., Wang,C., Muller,N.,
            Mayans,O., Schleheck,D. and Hartig,J.S.
  TITLE     Widespread bacterial lysine degradation proceeding via glutarate
            and L-2-hydroxyglutarate
  JOURNAL   Nat Commun 9 (1), 5071 (2018)
   PUBMED   30498244
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 345)
  AUTHORS   Marschall,C., Labrousse,V., Kreimer,M., Weichart,D., Kolb,A. and
            Hengge-Aronis,R.
  TITLE     Molecular analysis of the regulation of csiD, a carbon
            starvation-inducible gene in Escherichia coli that is exclusively
            dependent on sigma s and requires activation by cAMP-CRP
  JOURNAL   J Mol Biol 276 (2), 339-353 (1998)
   PUBMED   9512707
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF002814.1
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK02963
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..345
                     /organism="Shigella flexneri"
                     /db_xref="taxon:623"
     gene            1..345
                     /gene="glaH"
     Protein         1..345
                     /product="glutarate dioxygenase GlaH"
                     /EC_number="1.14.11.64"
                     /GO_function="GO:0050498 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen, with 2-oxoglutarate as one donor, and
                     the other dehydrogenated [Evidence IEA]"
                     /calculated_mol_wt=39854
     Region          42..342
                     /region_name="PRK02963"
                     /note="carbon starvation induced protein CsiD"
                     /db_xref="CDD:235092"
     Site            order(165,198,200,205,237,329,331)
                     /site_type="other"
                     /note="substrate binding pocket [chemical binding]"
                     /db_xref="CDD:238154"
     Site            order(195,197,312,325)
                     /site_type="active"
                     /db_xref="CDD:238154"
     Site            order(195,197,312)
                     /site_type="other"
                     /note="iron coordination sites [ion binding]"
                     /db_xref="CDD:238154"
ORIGIN      
        1 msllcaffrn vdifrlwlrn ehrhvtlhli rgsllmnalt avqnnavdsg qdysgftlip
       61 saqsprllel tfteqttkqf leqvaewpvq aleyksflrf rvgkilddlc anqlqplllk
      121 tllnraegal linavgiddv aqademvkla tavahligrs nfdamsgqyy arfvvknvdn
      181 sdsylrqphr vmelhndgty veeitdyvlm mkiddwehld hyfrhplarr pmrfaappsk
      241 nvskdvfhpv fdvdqqgrpv mryidqfvqp kdfeegvwls elsdaietsk gilsvpvpvg
      301 kfllinnlfw lhgrdrftph pdlrrelmrq rgyfayathh yqthq