MULTISPECIES: GDP-mannose 4,6-dehydratase [Salmonella].

LOCUS       WP_000048160             373 aa            linear   BCT 01-JUL-2024
ACCESSION   WP_000048160
VERSION     WP_000048160.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 373)
  AUTHORS   Sullivan,F.X., Kumar,R., Kriz,R., Stahl,M., Xu,G.Y., Rouse,J.,
            Chang,X.J., Boodhoo,A., Potvin,B. and Cumming,D.A.
  TITLE     Molecular cloning of human GDP-mannose 4,6-dehydratase and
            reconstitution of GDP-fucose biosynthesis in vitro
  JOURNAL   J Biol Chem 273 (14), 8193-8202 (1998)
   PUBMED   9525924
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR01472.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..373
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..373
                     /gene="gmd"
     Protein         1..373
                     /product="GDP-mannose 4,6-dehydratase"
                     /EC_number="4.2.1.47"
                     /GO_function="GO:0008446 - GDP-mannose 4,6-dehydratase
                     activity [Evidence IEA]"
                     /GO_process="GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /GO_process="GO:0019673 - GDP-mannose metabolic process
                     [Evidence IEA]"
                     /calculated_mol_wt=41794
     Region          3..355
                     /region_name="Gmd"
                     /note="GDP-D-mannose dehydratase [Cell
                     wall/membrane/envelope biogenesis]; COG1089"
                     /db_xref="CDD:440706"
ORIGIN      
        1 mskvalitgv tgqdgsylae fllekgyevh gikrrassfn tervdhiyqd phscnpkfhl
       61 hygdltdasn ltrilqevqp devynlgams hvavsfespe ytadvdamgt lrlleairfl
      121 glekktrfyq astselyglv qeipqkettp fyprspyava klyaywitvn yresygiyac
      181 ngilfnhesp rrgetfvtrk itraianiaq glesclylgn mdslrdwgha kdyvrmqwmm
      241 lqqeqpedfv iatgvqysvr qfvelaaaql giklrfegeg inekgivvsv tghdapgvkp
      301 gdvivavdpr yfrpaevetl lgdpskahek lgwkpeitls emvsemvand leaakkhsll
      361 kshgyevaia les