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LOCUS WP_000046824 433 aa linear BCT 10-DEC-2019 coli]. ACCESSION WP_000046824 VERSION WP_000046824.1 KEYWORDS RefSeq. SOURCE Escherichia coli ORGANISM Escherichia coli Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia. REFERENCE 1 (residues 1 to 433) AUTHORS Hur,S., Stroud,R.M. and Finer-Moore,J. TITLE Substrate recognition by RNA 5-methyluridine methyltransferases and pseudouridine synthases: a structural perspective JOURNAL J. Biol. Chem. 281 (51), 38969-38973 (2006) PUBMED 17085441 REFERENCE 2 (residues 1 to 433) AUTHORS Lee,T.T., Agarwalla,S. and Stroud,R.M. TITLE A unique RNA Fold in the RumA-RNA-cofactor ternary complex contributes to substrate selectivity and enzymatic function JOURNAL Cell 120 (5), 599-611 (2005) PUBMED 15766524 REFERENCE 3 (residues 1 to 433) AUTHORS Agarwalla,S., Stroud,R.M. and Gaffney,B.J. TITLE Redox reactions of the iron-sulfur cluster in a ribosomal RNA methyltransferase, RumA: optical and EPR studies JOURNAL J. Biol. Chem. 279 (33), 34123-34129 (2004) PUBMED 15181002 REFERENCE 4 (residues 1 to 433) AUTHORS Lee,T.T., Agarwalla,S. and Stroud,R.M. TITLE Crystal structure of RumA, an iron-sulfur cluster containing E. coli ribosomal RNA 5-methyluridine methyltransferase JOURNAL Structure 12 (3), 397-407 (2004) PUBMED 15016356 REFERENCE 5 (residues 1 to 433) AUTHORS Madsen,C.T., Mengel-Jorgensen,J., Kirpekar,F. and Douthwaite,S. TITLE Identifying the methyltransferases for m(5)U747 and m(5)U1939 in 23S rRNA using MALDI mass spectrometry JOURNAL Nucleic Acids Res. 31 (16), 4738-4746 (2003) PUBMED 12907714 REFERENCE 6 (residues 1 to 433) AUTHORS Agarwalla,S., Kealey,J.T., Santi,D.V. and Stroud,R.M. TITLE Characterization of the 23 S ribosomal RNA m5U1939 methyltransferase from Escherichia coli JOURNAL J. Biol. Chem. 277 (11), 8835-8840 (2002) PUBMED 11779873 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: HMM Evidence Accession :: NF009639.0 Evidence Source :: NCBI Protein Cluster (PRK) Source Identifier :: PRK13168 ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..433 /organism="Escherichia coli" /db_xref="taxon:562" gene 1..433 /gene="rlmD" Protein 1..433 /product="23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD" /EC_number="2.1.1.190" /GO_function="GO:0008173 - RNA methyltransferase activity [Evidence IEA]" /GO_process="GO:0006396 - RNA processing [Evidence IEA]" /calculated_mol_wt=48024 Region 2..431 /region_name="rumA" /note="23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD; PRK13168" /db_xref="CDD:237291" ORIGIN 1 maqfysakrr tttrqiitvs vndldsfgqg varhngktlf ipgllpqena evtvtedkkq 61 yarakvvrrl sdsperetpr cphfgvcggc qqqhasvdlq qrsksaalar lmkhevsevi 121 advpwgyrrr arlslnylpk tqqlqmgfrk agssdivdvk qcpilvpqle allpkvracl 181 gslqamrhlg hvelvqatsg tlmilrhtap lssadrekle rfshsegldl ylapdseile 241 tvsgempwyd snglrltfsp rdfiqvnagv nqkmvarale wlevepedrv ldlfcgmgnf 301 tlplatqaas vvgvegvpal vekgqqnarl nclqnvtfyh enleedvtkq pwakngfdkv 361 lldparagaa gvmqqiikle pirivyvscn patlardsea llkagytiar lamldmfpht 421 ghlesmvlfs rvk