lysylphosphatidylglycerol synthase transmembrane domain-containing

LOCUS       WP_000045455             318 aa            linear   BCT 20-JAN-2025
            protein [Escherichia coli].
ACCESSION   WP_000045455
VERSION     WP_000045455.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 318)
  AUTHORS   Oku,Y., Kurokawa,K., Ichihashi,N. and Sekimizu,K.
  TITLE     Characterization of the Staphylococcus aureus mprF gene, involved
            in lysinylation of phosphatidylglycerol
  JOURNAL   Microbiology (Reading) 150 (Pt 1), 45-51 (2004)
   PUBMED   14702396
REFERENCE   2  (residues 1 to 318)
  AUTHORS   Kristian,S.A., Durr,M., Van Strijp,J.A., Neumeister,B. and
            Peschel,A.
  TITLE     MprF-mediated lysinylation of phospholipids in Staphylococcus
            aureus leads to protection against oxygen-independent neutrophil
            killing
  JOURNAL   Infect Immun 71 (1), 546-549 (2003)
   PUBMED   12496209
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10001278
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..318
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     Protein         1..318
                     /product="lysylphosphatidylglycerol synthase transmembrane
                     domain-containing protein"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /calculated_mol_wt=35715
     Region          12..>292
                     /region_name="bifunc_MprF"
                     /note="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF; NF033480"
                     /db_xref="CDD:468043"
ORIGIN      
        1 mskshprwrl akkiltwlff iavivllvvy akkvdweevw kvirdynrva llsavglvvv
       61 syliygcydl larfycghkl akrqvmlvsf icyafnltls twvggigmry rlysrlglpg
      121 stitrifsls ittnwlgyil lagiiftagv velpdhwyvd qttlrilgig llmiiavylw
      181 fcafakhrhm tikgqklvlp swkfalaqml issvnwmvmg aiiwlllgqs vnyffvlgvl
      241 lvssiagviv hvpagigvle avfiallage htskgtiiaa llayrvlyyf iplllalicy
      301 lllesqakkl rakneaam