MULTISPECIES: glutamate-1-semialdehyde 2,1-aminomutase

LOCUS       WP_000045315             426 aa            linear   BCT 01-JUL-2024
            [Escherichia].
ACCESSION   WP_000045315
VERSION     WP_000045315.1
KEYWORDS    RefSeq.
SOURCE      Escherichia
  ORGANISM  Escherichia
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00713.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Escherichia"
                     /db_xref="taxon:561"
     gene            1..426
                     /gene="hemL"
     Protein         1..426
                     /product="glutamate-1-semialdehyde 2,1-aminomutase"
                     /EC_number="5.4.3.8"
                     /GO_function="GO:0042286 - glutamate-1-semialdehyde
                     2,1-aminomutase activity [Evidence IEA]"
                     /GO_process="GO:0033014 - tetrapyrrole biosynthetic
                     process [Evidence IEA]"
                     /calculated_mol_wt=45235
     Region          1..426
                     /region_name="PRK00062"
                     /note="glutamate-1-semialdehyde 2,1-aminomutase"
                     /db_xref="CDD:234607"
     Site            order(114..116,142..143,145,204,237,239..240,265)
                     /site_type="active"
                     /note="inhibitor-cofactor binding pocket [active]"
                     /db_xref="CDD:99735"
     Site            order(115..116,142..143,204,237,240,265)
                     /site_type="other"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]"
                     /db_xref="CDD:99735"
     Site            265
                     /site_type="active"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99735"
ORIGIN      
        1 msksenlysa arelipggvn spvraftgvg gtplfiekad gaylydvdgk ayidyvgswg
       61 pmvlghnhpa irnavieaae rglsfgapte mevkmaqlvt elvptmdmvr mvnsgteatm
      121 sairlargft grdkiikfeg cyhghadcll vkagsgaltl gqpnspgvpa dfakytltct
      181 yndlasvraa feqypqeiac iivepvagnm ncvpplpefl pglralcdef galliidevm
      241 tgfrvalaga qdyygvvpdl tclgkiiggg mpvgafggrr dvmdalaptg pvyqagtlsg
      301 npiamaagfa clnevaqpgv hetldelttr laeglleaae eagiplvvnh vggmfgifft
      361 daesvtcyqd vmacdverfk rffhmmldeg vylapsafea gfmsvahsme dinntidaar
      421 rvfakl