dethiobiotin synthase [Escherichia coli].

FASTA View on NCBI
LOCUS       WP_000044849             225 aa            linear   BCT 04-JUN-2024
ACCESSION   WP_000044849
VERSION     WP_000044849.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 225)
  AUTHORS   Yang,G., Sandalova,T., Lohman,K., Lindqvist,Y. and Rendina,A.R.
  TITLE     Active site mutants of Escherichia coli dethiobiotin synthetase:
            effects of mutations on enzyme catalytic and structural properties
  JOURNAL   Biochemistry 36 (16), 4751-4760 (1997)
   PUBMED   9125495
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00347.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..225
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..225
                     /gene="bioD"
     Protein         1..225
                     /product="dethiobiotin synthase"
                     /EC_number="6.3.3.3"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0004141 - dethiobiotin synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0009102 - biotin biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=23934
     Region          2..224
                     /region_name="BioD"
                     /note="Dethiobiotin synthetase [Coenzyme transport and
                     metabolism]; COG0132"
                     /db_xref="CDD:439902"
ORIGIN      
        1 mskryfvtgt dtevgktvas callqaakaa gyrtagykpv asgsektpeg lrnsdalalq
       61 rnsslqldya tvnpytfaep tsphiisaqe grsiessvms sglraleqqa dwvlvegagg
      121 wftplsdtft fadwvtqeql pvilvvgvkl gcinhamlta qaiqhagltl agwvandvtp
      181 pgkrhaeymt tltrmipapl lgespwlaen penaatgkyi nlall