NADP-dependent phosphogluconate dehydrogenase [Escherichia coli].

LOCUS       WP_000043478             468 aa            linear   BCT 01-JUN-2019
ACCESSION   WP_000043478
VERSION     WP_000043478.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF006765.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK09287
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..468
                     /gene="gndA"
     Protein         1..468
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /EC_number="1.1.1.44"
                     /GO_function="GO:0004616 - phosphogluconate dehydrogenase
                     (decarboxylating) activity [Evidence IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /GO_process="GO:0006098 - pentose-phosphate shunt
                     [Evidence IEA]"
                     /calculated_mol_wt=51346
     Region          2..466
                     /region_name="Gnd"
                     /note="6-phosphogluconate dehydrogenase [Carbohydrate
                     transport and metabolism]; COG0362"
                     /db_xref="CDD:440131"
ORIGIN      
        1 mskqqigvvg mavmgrnlal niesrgytvs ifnrsrekte eviaenpgkk lvpyytvkef
       61 vesletprri llmvkagagt daaidslkpy ldkgdiiidg gntffqdtir rnrelsaegf
      121 nfigtgvsgg eegalkgpsi mpggqkeaye lvapiltkia avaedgepcv tyigadgagh
      181 yvkmvhngie ygdmqliaea ysllkgglnl tneelaqift ewnngelssy liditkdift
      241 kkdedgnylv dvildeaank gtgkwtsqsa ldlgeplsli tesvfaryis slkdqrvaas
      301 kvlsgpqaqp agdkaefiek vrralylgki vsyaqgfsql raaseeynwd lnygeiakif
      361 ragciiraqf lqkitdayae npqianllla pyfkqiaddy qqalrdvvay avqngipvpt
      421 faaavayyds yraavlpanl iqaqrdyfga htykridkeg vfhtewld