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MULTISPECIES: lipoyl synthase [Bacteria].


LOCUS       WP_000042632             321 aa            linear   BCT 27-SEP-2019
ACCESSION   WP_000042632
VERSION     WP_000042632.1
KEYWORDS    RefSeq.
SOURCE      Bacteria (eubacteria)
  ORGANISM  Bacteria
            Unclassified.
REFERENCE   1  (residues 1 to 321)
  AUTHORS   Ollagnier-de Choudens,S. and Fontecave,M.
  TITLE     The lipoate synthase from Escherichia coli is an iron-sulfur
            protein
  JOURNAL   FEBS Lett. 453 (1-2), 25-28 (1999)
   PUBMED   10403368
REFERENCE   2  (residues 1 to 321)
  AUTHORS   Sulo,P. and Martin,N.C.
  TITLE     Isolation and characterization of LIP5. A lipoate biosynthetic
            locus of Saccharomyces cerevisiae
  JOURNAL   J. Biol. Chem. 268 (23), 17634-17639 (1993)
   PUBMED   8349643
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00510.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Bacteria"
                     /db_xref="taxon:2"
     gene            1..321
                     /gene="lipA"
     Protein         1..321
                     /product="lipoyl synthase"
                     /EC_number="2.8.1.8"
                     /GO_function="GO:0016992 - lipoate synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster
                     binding [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /GO_process="GO:0009107 - lipoate biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=35941
     Region          22..321
                     /region_name="LipA"
                     /note="Lipoate synthase [Coenzyme transport and
                     metabolism]; COG0320"
                     /db_xref="CDD:440089"
ORIGIN      
        1 mskpivmerg vkyrdadkma lipvknvate reallrkpew mkiklpadst riqgikaamr
       61 knglhsvcee ascpnlaecf nhgtatfmil gaictrrcpf cdvahgrpva pdanepvkla
      121 qtiadmalry vvitsvdrdd lrdggaqhfa dcitaireks pqikietlvp dfrgrmdral
      181 diltatppdv fnhnlenvpr iyrqvrpgad ynwslkller fkeahpeipt ksglmvglge
      241 tneeiievmr dlrrhgvtml tlgqylqpsr hhlpvqryvs pdefdemkae alamgfthaa
      301 cgpfvrssyh adlqakgmev k