MULTISPECIES: 3-isopropylmalate dehydrogenase [Escherichia].

LOCUS       WP_000042351             363 aa            linear   BCT 20-NOV-2023
ACCESSION   WP_000042351
VERSION     WP_000042351.1
KEYWORDS    RefSeq.
SOURCE      Escherichia
  ORGANISM  Escherichia
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 363)
  AUTHORS   Dean,A.M. and Golding,G.B.
  TITLE     Protein engineering reveals ancient adaptive replacements in
            isocitrate dehydrogenase
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 94 (7), 3104-3109 (1997)
   PUBMED   9096353
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00169.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..363
                     /organism="Escherichia"
                     /db_xref="taxon:561"
     gene            1..363
                     /gene="leuB"
     Protein         1..363
                     /product="3-isopropylmalate dehydrogenase"
                     /EC_number="1.1.1.85"
                     /GO_function="GO:0003862 - 3-isopropylmalate dehydrogenase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009098 - leucine biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=39384
     Region          3..362
                     /region_name="PRK00772"
                     /note="3-isopropylmalate dehydrogenase; Provisional"
                     /db_xref="CDD:234832"
ORIGIN      
        1 msknyhiavl pgdgigpevm tqalkvldav rnrfamritt shydvggaai dnhgqplppa
       61 tvegceqada vlfgsvggpk wehlppdqqp ergallplrk hfklfsnlrp aklyqgleaf
      121 cplradiaan gfdilcvrel tggiyfgqpk gregsgqyek afdtevyhrf eieriariaf
      181 esarkrrhkv tsidkanvlq ssilwreivn eiateypdie lahmyidnat mqlikdpsqf
      241 dvllcsnlfg dilsdecami tgsmgmlpsa slneqgfgly epaggsapdi agknianpia
      301 qilslalllr ysldaddaas aierainral eegirtgdla rgaaavstde mgdiiaryva
      361 egv