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MULTISPECIES: diacylglycerol kinase [Enterobacteriaceae].


LOCUS       WP_000024297             119 aa            linear   BCT 27-JUL-2024
ACCESSION   WP_000024297
VERSION     WP_000024297.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 119)
  AUTHORS   Van Horn,W.D. and Sanders,C.R.
  TITLE     Prokaryotic diacylglycerol kinase and undecaprenol kinase
  JOURNAL   Annu Rev Biophys 41, 81-101 (2012)
   PUBMED   22224599
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10198050
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..119
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     Protein         1..119
                     /product="diacylglycerol kinase"
                     /EC_number="2.7.1.107"
                     /GO_function="GO:0004143 - ATP-dependent diacylglycerol
                     kinase activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic
                     process [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /calculated_mol_wt=12755
     Region          9..117
                     /region_name="DAGK_IM"
                     /note="Integral membrane diacylglycerol kinase; cd14264"
                     /db_xref="CDD:260133"
     Site            order(9,14,18,21,30,33,35,70,73..74,77,81..82,94..96,
                     98..99,101)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:260133"
     Site            order(16..22,24..25,53..55,57..58,61,64,68..69,71..72,
                     74..76,78..80,82..83,88,90..91,94,97,100..101,104..105,
                     108,112,115..116)
                     /site_type="other"
                     /note="trimer interface [polypeptide binding]"
                     /db_xref="CDD:260133"
     Site            order(20,29,70,77,81,95..96)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:260133"
     Site            order(29,77)
                     /site_type="other"
                     /note="Zn binding site [ion binding]"
                     /db_xref="CDD:260133"
ORIGIN      
        1 mantttgvtr iikaagyswk glcaawryea afrqecilvl saliisfwld vdsvtrvlli
       61 gsammviive iinsaieavv drigsehhel sgrakdmgsa avlitilvai iiwgvllls