MFS transporter [Escherichia coli].

LOCUS       WP_000018366             461 aa            linear   BCT 28-JUL-2024
ACCESSION   WP_000018366
VERSION     WP_000018366.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 461)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 461)
  AUTHORS   Zhang,X.C., Zhao,Y., Heng,J. and Jiang,D.
  TITLE     Energy coupling mechanisms of MFS transporters
  JOURNAL   Protein Sci 24 (10), 1560-1579 (2015)
   PUBMED   26234418
REFERENCE   3  (residues 1 to 461)
  AUTHORS   Yan,N.
  TITLE     Structural advances for the major facilitator superfamily (MFS)
            transporters
  JOURNAL   Trends Biochem Sci 38 (3), 151-159 (2013)
   PUBMED   23403214
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11489668
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     Protein         1..461
                     /product="MFS transporter"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=50865
     Region          19..457
                     /region_name="gph"
                     /note="sugar (Glycoside-Pentoside-Hexuronide) transporter;
                     TIGR00792"
                     /db_xref="CDD:273270"
ORIGIN      
        1 mshittedpa tlrlpfkekl sygigdlasn illdigtlyl lkfytdvlgl pgtyggiifl
       61 iskfftaftd mgtgimldsr rkigpkgkfr pfilyasfpv tllaianfig tpfdvtgktv
      121 matilfmlyg lffsmmncsy gamvpaitkn pneraslaaw rqggatlgll lctvgfvpvm
      181 nliegnqqlg yifaatlfsl fgllfmwicy sgvkeryvet qpanpaqkpg llqsfraiag
      241 nrplfilcia nlctlgafnv klaiqvyytq yvlndpills ymgffsmgci figvflmpga
      301 vrrfgkkkvy igglliwvlg dllnyffsgg svsfvafscl affgsafvns lnwalvsdtv
      361 eygewrtgvr segtvytgft ffrkvsqala gffpgwmltq igyvpnvaqa dhtieglrql
      421 ifiypsalav vtivamgcfy slnekmyvri veeiearkrt a