MULTISPECIES: MFS transporter [Salmonella].

LOCUS       WP_000017194             433 aa            linear   BCT 01-JAN-2025
ACCESSION   WP_000017194
VERSION     WP_000017194.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 433)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 433)
  AUTHORS   Zhang,X.C., Zhao,Y., Heng,J. and Jiang,D.
  TITLE     Energy coupling mechanisms of MFS transporters
  JOURNAL   Protein Sci 24 (10), 1560-1579 (2015)
   PUBMED   26234418
REFERENCE   3  (residues 1 to 433)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13024289
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     Protein         1..433
                     /product="MFS transporter"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=46853
     Region          10..421
                     /region_name="MFS_ShiA_like"
                     /note="Shikimate transporter and similar proteins of the
                     Major Facilitator Superfamily; cd17369"
                     /db_xref="CDD:340927"
     Site            order(23..24,27..28,31,70,128..129,131..133,136,156,
                     159..160,163,251,254..255,258..260,263,291,295,348..349,
                     353,357,373,376..377,380..381,384)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340927"
ORIGIN      
        1 msgtynatir rvvvsawign sieyydflly glasalvfgp lffpgasplt atlssfasfg
       61 vgfisrplga lffgnrgdtl grkntllitl ggmgavtfli gclpsyasig alapallvil
      121 rflqgfmvgg ewggamlmvv eyaagkhrgr lsalsqtggl tgqllatgvf ivvtqlpqea
      181 llswgwripf llsallvlpg lymrhrldet pvfrafkkqq ainhrqqree rpvvkvvreq
      241 wrsilliiil rfaesvpffl atvfavswat tqlgiaslti lyivmftcll aypmhvlfgi
      301 msdrrgcrqv yifgalfvaa mafpffwlle srslilmtmg yvllinighn slnavqpsff
      361 aglfhppvry sgssigaqlg avvaggftpf iakalsavyd nswalvagyv vltalasafa
      421 akiapetvlp hsp