primase-helicase zinc-binding domain-containing protein

LOCUS       WP_000016225             777 aa            linear   BCT 01-MAR-2025
            [Escherichia coli].
ACCESSION   WP_000016225
VERSION     WP_000016225.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 777)
  AUTHORS   Kato,M., Ito,T., Wagner,G., Richardson,C.C. and Ellenberger,T.
  TITLE     Modular architecture of the bacteriophage T7 primase couples RNA
            primer synthesis to DNA synthesis
  JOURNAL   Mol Cell 11 (5), 1349-1360 (2003)
   PUBMED   12769857
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF019878.6
            Evidence Source    :: EMBL-EBI
            Source Identifier  :: PF08273.17
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..777
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     Protein         1..777
                     /product="primase-helicase zinc-binding domain-containing
                     protein"
                     /GO_function="GO:0003896 - DNA primase activity [Evidence
                     IEA]"
                     /GO_function="GO:0004386 - helicase activity [Evidence
                     IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence
                     IEA]"
                     /calculated_mol_wt=84955
     Region          1..417
                     /region_name="COG4643"
                     /note="Uncharacterized domain associated with
                     phage/plasmid primase [Mobilome: prophages, transposons]"
                     /db_xref="CDD:443681"
     Region          350..765
                     /region_name="COG3378"
                     /note="DNA primase, phage- or plasmid-associated
                     [Mobilome: prophages, transposons]"
                     /db_xref="CDD:442605"
ORIGIN      
        1 msgmkvsqae kaarghwsri lpalgvnvlk nrhqpcpvca gkdrfrfddq egrgtwfcnq
       61 cgagdglalv skvldvgise aadringiig nllpvsqgml esgspekedg rkaaavlaar
      121 lfdksrqttg nayltskgfp alpcreltam hkvggvafra gdlvvplyad gelvnlqlin
      181 anggkcflkg gqvknafylv egtakaakrl wiaegyatal tinyltgdav mvafssvnfl
      241 slasiacsey pthqiiiaad rdlngagqtr gaavtgacnc tmalppvfgd wndaftqnge
      301 eatrhaihev ikpavaspfd tmseaeftal svsekaqrvv dhyknslavd pngqllsrye
      361 agawkviyya dfardvaalf qrldapfssa kiaslvetlk livpqqqnpa rqligfrngv
      421 ldtrtglfsp hdkkhwlrtl cevdytqpvd geslethapa fwrwldraag fnpekrdiil
      481 aalfmvlanr ydwqlflevt gpggsgksil aeiatmlage dnatsatiem lespreraal
      541 igfslirlpd qekwsgdgag lkaitggdav svdpkyqnay sthipavila vnnnpmrftd
      601 rsggvsrrrv ilhfpdqiap eerdtqlkek iaselavivr qlmqrfsdpm sartllqsqq
      661 nsdealtikr dadsafdfcg ylevlpdttg mfmgnanivp rqprtylyha ylvymeangy
      721 kntlsltmfg kglplmlkey glqyekrrtn qgmqtnlalr eesnadwlpk cdefaak