1-deoxy-D-xylulose-5-phosphate synthase [Shigella flexneri].

LOCUS       WP_000006840             620 aa            linear   BCT 28-FEB-2022
ACCESSION   WP_000006840
VERSION     WP_000006840.1
KEYWORDS    RefSeq.
SOURCE      Shigella flexneri
  ORGANISM  Shigella flexneri
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Shigella.
REFERENCE   1  (residues 1 to 620)
  AUTHORS   Lois,L.M., Campos,N., Putra,S.R., Danielsen,K., Rohmer,M. and
            Boronat,A.
  TITLE     Cloning and characterization of a gene from Escherichia coli
            encoding a transketolase-like enzyme that catalyzes the synthesis
            of D-1-deoxyxylulose 5-phosphate, a common precursor for
            isoprenoid, thiamin, and pyridoxol biosynthesis
  JOURNAL   Proc Natl Acad Sci U S A 95 (5), 2105-2110 (1998)
   PUBMED   9482846
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00204.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..620
                     /organism="Shigella flexneri"
                     /db_xref="taxon:623"
     gene            1..620
                     /gene="dxs"
     Protein         1..620
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /EC_number="2.2.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /calculated_mol_wt=67516
     Region          7..620
                     /region_name="Dxs"
                     /note="Deoxyxylulose-5-phosphate synthase [Coenzyme
                     transport and metabolism, Lipid transport and metabolism];
                     COG1154"
                     /db_xref="CDD:440768"
ORIGIN      
        1 msfdiakypt lalvdstqel rllpneslpk lcdelrryll dsvsrssghf asglgtvelt
       61 valhyvyntp fdqliwdvgh qayphkiltg rrdkigtirq kgglhpfpwr geseydvlsv
      121 ghsstsisag igiavaaeke gknrrtvcvi gdgaitagma feamnhagdi rpdmlvvlnd
      181 nemsisenvg alnnhlaqll sgklysslre ggkkvfsgvp pikellkrte ehikgmvvpg
      241 tlfeelgfny igpvdghdvl glittlknmr dlkgpqflhi mtkkgrgyep aekdpitfha
      301 vpkfdpssgc lpkssgglps yskifgdwlc etaakdnklm aitpamregs gmvefsrkfp
      361 dryfdvaiae qhavtfaagl aiggykpiva iystflqray dqvlhdvaiq klpvlfaidr
      421 agivgadgqt hqgafdlsyl rcipemvimt psdenecrqm lytgyhyndg psavryprgn
      481 avgveltple klpigkgivk rrgeklviln fgtlmpetak vaeslnatlv dmrfvkplde
      541 alilemaash ealvtveena imggagsgvn evlmahrkpv pvlniglpdf fipqgtqeem
      601 raelgldaag meakikawla