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MULTISPECIES: 1-deoxy-D-xylulose-5-phosphate synthase [Salmonella].


LOCUS       WP_000006777             620 aa            linear   BCT 28-FEB-2022
ACCESSION   WP_000006777
VERSION     WP_000006777.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 620)
  AUTHORS   Lois,L.M., Campos,N., Putra,S.R., Danielsen,K., Rohmer,M. and
            Boronat,A.
  TITLE     Cloning and characterization of a gene from Escherichia coli
            encoding a transketolase-like enzyme that catalyzes the synthesis
            of D-1-deoxyxylulose 5-phosphate, a common precursor for
            isoprenoid, thiamin, and pyridoxol biosynthesis
  JOURNAL   Proc Natl Acad Sci U S A 95 (5), 2105-2110 (1998)
   PUBMED   9482846
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00204.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..620
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..620
                     /gene="dxs"
     Protein         1..620
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /EC_number="2.2.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /calculated_mol_wt=67337
     Region          7..620
                     /region_name="Dxs"
                     /note="Deoxyxylulose-5-phosphate synthase [Coenzyme
                     transport and metabolism, Lipid transport and metabolism];
                     COG1154"
                     /db_xref="CDD:440768"
ORIGIN      
        1 msfdiakypt lalvdstqel rllpkeslpk lcdelrryll dsvsrssghf asglgtvelt
       61 valhyvyntp fdqliwdvgh qayphkiltg rrdkigtirq kgglhpfpwr geseydvlsv
      121 ghsstsisag igiavaaeke gkdrrtvcvi gdgaitagma feamnhagdi rpdmlvilnd
      181 nemsisenvg alnnhlaqll sgklysslre ggkkvfsgvp pikellkrte ehikgmvvpg
      241 tlfeelgfny igpvdghdvm glistlknmr dlkgpqflhi mtkkgrgyep aekdpitfha
      301 vpkfdpssgc lpkssgglpg yskifgdwlc etaakdsklm aitpamregs gmvefsrkfp
      361 dryfdvaiae qhavtfaagl aiggykpvva iystflqray dqvihdvaiq klpvmfaidr
      421 agivgadgqt hqgafdlsyl rcipdmvimt psdenecrqm lftgyhyndg ptavryprgn
      481 aqgvaltple klpigkglvk rhgeklailn fgtlmpeaak vaealnatlv dmrfvkpldd
      541 tlilemaaqh dalvtleena imggagsgvn evlmahrkpv pvlniglpdf fipqgtqeea
      601 raelgldaag ieakikawla