lysine--tRNA ligase [Escherichia coli].

LOCUS       WP_000003075             505 aa            linear   BCT 04-JUN-2024
ACCESSION   WP_000003075
VERSION     WP_000003075.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00499.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..505
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..505
                     /gene="lysS"
     Protein         1..505
                     /product="lysine--tRNA ligase"
                     /EC_number="6.1.1.6"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /calculated_mol_wt=57501
     Region          14..503
                     /region_name="lysS"
                     /note="lysyl-tRNA synthetase; Reviewed; PRK00484"
                     /db_xref="CDD:234778"
     Site            209..213
                     /site_type="other"
                     /note="motif 1"
                     /db_xref="CDD:238398"
     Site            order(241,263,265,271,275,415,422,425,429,481)
                     /site_type="active"
                     /db_xref="CDD:238398"
     Site            262..265
                     /site_type="other"
                     /note="motif 2"
                     /db_xref="CDD:238398"
     Site            478..481
                     /site_type="other"
                     /note="motif 3"
                     /db_xref="CDD:238398"
ORIGIN      
        1 mseqhaqgad avvdlnnelk trreklanlr eqgiafpndf rrdhtsdqlh aefdgkenee
       61 lealnievav agrmmtrrim gkasfvtlqd vggriqlyva rddlpegvyn eqfkkwdlgd
      121 ilgakgklfk tktgelsihc telrlltkal rplpdkfhgl qdqearyrqr yldlisndes
      181 rntfkvrsqi lsgirqfmvn rgfmevetpm mqvipggaaa rpfithhnal dldmylriap
      241 elylkrlvvg gfervfeinr nfrnegisvr hnpeftmmel ymayadykdl ielteslfrt
      301 laqdilgkte vtygdvtldf gkpfekltmr eaikkyrpet dmadldnfds akaivesigi
      361 hvekswglgr ivteifeeva eahliqptfi teypaevspl arrndvnpei tdrfeffigg
      421 reigngfsel ndaedqaqrf ldqvaakdag ddeamfyded yvtalehglp ptaglgigid
      481 rmvmlftnsh tirdvilfpa mrpvk