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DUF5107 domain-containing protein YphG [Escherichia coli str. K-12


LOCUS       NP_417044               1093 aa            linear   CON 09-MAR-2022
            substr. MG1655].
ACCESSION   NP_417044
VERSION     NP_417044.4
DBLINK      BioProject: PRJNA57779
            BioSample: SAMN02604091
DBSOURCE    REFSEQ: accession NC_000913.3
KEYWORDS    RefSeq.
SOURCE      Escherichia coli str. K-12 substr. MG1655
  ORGANISM  Escherichia coli str. K-12 substr. MG1655
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 1093)
  AUTHORS   Riley,M., Abe,T., Arnaud,M.B., Berlyn,M.K., Blattner,F.R.,
            Chaudhuri,R.R., Glasner,J.D., Horiuchi,T., Keseler,I.M., Kosuge,T.,
            Mori,H., Perna,N.T., Plunkett,G. III, Rudd,K.E., Serres,M.H.,
            Thomas,G.H., Thomson,N.R., Wishart,D. and Wanner,B.L.
  TITLE     Escherichia coli K-12: a cooperatively developed annotation
            snapshot--2005
  JOURNAL   Nucleic Acids Res. 34 (1), 1-9 (2006)
   PUBMED   16397293
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 1093)
  AUTHORS   Hayashi,K., Morooka,N., Yamamoto,Y., Fujita,K., Isono,K., Choi,S.,
            Ohtsubo,E., Baba,T., Wanner,B.L., Mori,H. and Horiuchi,T.
  TITLE     Highly accurate genome sequences of Escherichia coli K-12 strains
            MG1655 and W3110
  JOURNAL   Mol. Syst. Biol. 2, 2006 (2006)
   PUBMED   16738553
REFERENCE   3  (residues 1 to 1093)
  AUTHORS   Blattner,F.R., Plunkett,G. III, Bloch,C.A., Perna,N.T., Burland,V.,
            Riley,M., Collado-Vides,J., Glasner,J.D., Rode,C.K., Mayhew,G.F.,
            Gregor,J., Davis,N.W., Kirkpatrick,H.A., Goeden,M.A., Rose,D.J.,
            Mau,B. and Shao,Y.
  TITLE     The complete genome sequence of Escherichia coli K-12
  JOURNAL   Science 277 (5331), 1453-1462 (1997)
   PUBMED   9278503
REFERENCE   4  (residues 1 to 1093)
  AUTHORS   Arnaud,M., Berlyn,M.K.B., Blattner,F.R., Galperin,M.Y.,
            Glasner,J.D., Horiuchi,T., Kosuge,T., Mori,H., Perna,N.T.,
            Plunkett,G. III, Riley,M., Rudd,K.E., Serres,M.H., Thomas,G.H. and
            Wanner,B.L.
  TITLE     Workshop on Annotation of Escherichia coli K-12
  JOURNAL   Unpublished
  REMARK    Woods Hole, Mass., on 14-18 November 2003 (sequence corrections)
REFERENCE   5  (residues 1 to 1093)
  AUTHORS   Glasner,J.D., Perna,N.T., Plunkett,G. III, Anderson,B.D.,
            Bockhorst,J., Hu,J.C., Riley,M., Rudd,K.E. and Serres,M.H.
  TITLE     ASAP: Escherichia coli K-12 strain MG1655 version m56
  JOURNAL   Unpublished
  REMARK    ASAP download 10 June 2004 (annotation updates)
REFERENCE   6  (residues 1 to 1093)
  AUTHORS   Hayashi,K., Morooka,N., Mori,H. and Horiuchi,T.
  TITLE     A more accurate sequence comparison between genomes of Escherichia
            coli K12 W3110 and MG1655 strains
  JOURNAL   Unpublished
  REMARK    GenBank accessions AG613214 to AG613378 (sequence corrections)
REFERENCE   7  (residues 1 to 1093)
  AUTHORS   Perna,N.T.
  TITLE     Escherichia coli K-12 MG1655 yqiK-rfaE intergenic region, genomic
            sequence correction
  JOURNAL   Unpublished
  REMARK    GenBank accession AY605712 (sequence corrections)
REFERENCE   8  (residues 1 to 1093)
  AUTHORS   Rudd,K.E.
  TITLE     A manual approach to accurate translation start site annotation: an
            E. coli K-12 case study
  JOURNAL   Unpublished
REFERENCE   9  (residues 1 to 1093)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-MAR-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   10 (residues 1 to 1093)
  AUTHORS   Blattner,F.R. and Plunkett,G. III.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-JUL-2014) Laboratory of Genetics, University of
            Wisconsin, 425G Henry Mall, Madison, WI 53706-1580, USA
  REMARK    Protein update by submitter
REFERENCE   11 (residues 1 to 1093)
  AUTHORS   Blattner,F.R. and Plunkett,G. III.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-NOV-2013) Laboratory of Genetics, University of
            Wisconsin, 425G Henry Mall, Madison, WI 53706-1580, USA
  REMARK    Protein update by submitter
REFERENCE   12 (residues 1 to 1093)
  AUTHORS   Blattner,F.R. and Plunkett,G. III.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-SEP-2013) Laboratory of Genetics, University of
            Wisconsin, 425G Henry Mall, Madison, WI 53706-1580, USA
  REMARK    Sequence update by submitter
REFERENCE   13 (residues 1 to 1093)
  AUTHORS   Rudd,K.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-FEB-2013) Department of Biochemistry and Molecular
            Biology, University of Miami Miller School of Medicine, 118 Gautier
            Bldg., Miami, FL 33136, USA
  REMARK    Sequence update by submitter
REFERENCE   14 (residues 1 to 1093)
  AUTHORS   Rudd,K.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-APR-2007) Department of Biochemistry and Molecular
            Biology, University of Miami Miller School of Medicine, 118 Gautier
            Bldg., Miami, FL 33136, USA
  REMARK    Annotation update from ecogene.org as a multi-database
            collaboration
REFERENCE   15 (residues 1 to 1093)
  AUTHORS   Plunkett,G. III.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-FEB-2006) Laboratory of Genetics, University of
            Wisconsin, 425G Henry Mall, Madison, WI 53706-1580, USA
  REMARK    Protein updates by submitter
REFERENCE   16 (residues 1 to 1093)
  AUTHORS   Plunkett,G. III.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-JUN-2004) Laboratory of Genetics, University of
            Wisconsin, 425G Henry Mall, Madison, WI 53706-1580, USA
  REMARK    Sequence update by submitter
REFERENCE   17 (residues 1 to 1093)
  AUTHORS   Plunkett,G. III.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-1998) Laboratory of Genetics, University of
            Wisconsin, 425G Henry Mall, Madison, WI 53706-1580, USA
REFERENCE   18 (residues 1 to 1093)
  AUTHORS   Blattner,F.R. and Plunkett,G. III.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-1997) Laboratory of Genetics, University of
            Wisconsin, 425G Henry Mall, Madison, WI 53706-1580, USA
REFERENCE   19 (residues 1 to 1093)
  AUTHORS   Blattner,F.R. and Plunkett,G. III.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-1997) Laboratory of Genetics, University of
            Wisconsin, 425G Henry Mall, Madison, WI 53706-1580, USA
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to AAC75602.
            
            On Dec 7, 2007 this sequence version replaced NP_417044.3.
            Changes to proteins and annotation made on March 7, 2022.  Current
            U00096 annotation updates are derived from EcoCyc
            https://ecocyc.org/.  Suggestions for updates can be sent to
            [email protected]. These updates are being generated from a
            collaboration  that includes EcoCyc, the University of Wisconsin,
            UniProtKB/Swiss-Prot, and the National Center for Biotechnology
            Information (NCBI).
            COMPLETENESS: full length.
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..1093
                     /organism="Escherichia coli str. K-12 substr. MG1655"
                     /strain="K-12"
                     /sub_strain="MG1655"
                     /db_xref="taxon:511145"
     Protein         1..1093
                     /product="DUF5107 domain-containing protein YphG"
                     /calculated_mol_wt=123702
     Region          40..343
                     /region_name="DUF5107"
                     /note="Domain of unknown function (DUF5107); pfam17128"
                     /db_xref="CDD:407262"
     Region          422..>605
                     /region_name="Spy"
                     /note="Predicted O-linked N-acetylglucosamine transferase,
                     SPINDLY family [Posttranslational modification, protein
                     turnover, chaperones]; COG3914"
                     /db_xref="CDD:443119"
     Region          495..523
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276809"
     Site            order(496,499..500,503..504,506,536,539..540,543..544,
                     546..547,570,573..574,577..578,581)
                     /site_type="other"
                     /note="putative protein binding surface [polypeptide
                     binding]"
                     /db_xref="CDD:276809"
     Region          534..564
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276809"
     Region          539..842
                     /region_name="LapB"
                     /note="Lipopolysaccharide biosynthesis regulator
                     YciM/LapB, contains six TPR domains and a C-terminal
                     metal-binding domain [Cell wall/membrane/envelope
                     biogenesis]; COG2956"
                     /db_xref="CDD:442196"
     Region          569..597
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276809"
     Region          603..631
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276809"
     Region          746..772
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276809"
     Region          749..>961
                     /region_name="LapB"
                     /note="Lipopolysaccharide biosynthesis regulator
                     YciM/LapB, contains six TPR domains and a C-terminal
                     metal-binding domain [Cell wall/membrane/envelope
                     biogenesis]; COG2956"
                     /db_xref="CDD:442196"
     Region          777..808
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276809"
     CDS             1..1093
                     /gene="yphG"
                     /locus_tag="b2549"
                     /gene_synonym="ECK2546"
                     /coded_by="complement(NC_000913.3:2679464..2682745)"
                     /transl_table=11
                     /db_xref="UniProtKB/Swiss-Prot:P76585"
                     /db_xref="ASAP:ABE-0008380"
                     /db_xref="ECOCYC:G7343"
                     /db_xref="GeneID:947021"
CONTIG      join(WP_001333903.1:1..1093)
ORIGIN      
        1 mtpvkvwqer veiptyetgp qdihpmflen rvyqgssgav ypygvtdtls eqktlkswqa
       61 vwlendyikv milpelggrv hrawdkvkqr dfvyhnevik palvgllgpw isggiefnwp
      121 qhhrpttfmp vdftleahed gaqtvwvget epmhglqvmt gftlrpdraa leiasrvyng
      181 natprhflww anpavkggeg hqsvfppdvt avfdhgkrav safpiatgty ykvdysagvd
      241 isryknvpvp tsymaeksqy dfvgawchde dggllhvanh hiapgkkqws wghsefgqaw
      301 dksltdnngp yielmtgifa dnqpdftwld ayeekrfeqy flpyhslgmv qnasrdavik
      361 lqrskrgiew glyaisplng yrlaireigk cnallddava lmpataiqgv lhginperlt
      421 ielsdadgni vlsyqehqpq alplpdvaka plaaqditst deawfigqhl eqyhhasrsp
      481 fdyylrgval dpldyrcnla lamleynrad fpqavayatq alkrahalnk npqcgqasli
      541 rasayerqgq yqqaeedfwr avwsgnskag gyyglarlaa rngnfdagld fcqqslracp
      601 tnqevlclhn lllvlsgrqd narvqrekll rdyplnatlw wlnwfdgrse salaqwrglc
      661 qgrdvnalmt agqlinwgmp tlaaemlnal dcqrtlplyl qasllpkaer gelvakaidv
      721 fpqfvrfpnt leevaalesi eecwfarhll acfyynkrsy nkaiafwqrc vemspefadg
      781 wrglaihawn kqhdyelaar yldnayqlap qdarllferd lldklsgatp ekrlarlenn
      841 leialkrddm taellnlwhl tgqadkaadi latrkfhpwe ggegkvtsqf ilnqllrawq
      901 hldarqpqqa cellhaalhy penlsegrlp gqtdndiwfw qaicanaqgd eteatrclrl
      961 aatgdrtini hsyyndqpvd ylfwqgmalr llgeqqtaqq lfsemkqwaq emaktsiead
     1021 ffavsqpdll slygdlqqqh kekclmvaml asaglgevaq yesaraelta inpawpkaal
     1081 fttvmpfifn rvh