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LOCUS NP_416170 1538 aa linear CON 09-MAR-2022 MG1655]. ACCESSION NP_416170 VERSION NP_416170.1 DBLINK BioProject: PRJNA57779 BioSample: SAMN02604091 DBSOURCE REFSEQ: accession NC_000913.3 KEYWORDS RefSeq. SOURCE Escherichia coli str. K-12 substr. MG1655 ORGANISM Escherichia coli str. K-12 substr. MG1655 Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia. REFERENCE 1 (residues 1 to 1538) AUTHORS Riley,M., Abe,T., Arnaud,M.B., Berlyn,M.K., Blattner,F.R., Chaudhuri,R.R., Glasner,J.D., Horiuchi,T., Keseler,I.M., Kosuge,T., Mori,H., Perna,N.T., Plunkett,G. III, Rudd,K.E., Serres,M.H., Thomas,G.H., Thomson,N.R., Wishart,D. and Wanner,B.L. TITLE Escherichia coli K-12: a cooperatively developed annotation snapshot--2005 JOURNAL Nucleic Acids Res. 34 (1), 1-9 (2006) PUBMED 16397293 REMARK Publication Status: Online-Only REFERENCE 2 (residues 1 to 1538) AUTHORS Hayashi,K., Morooka,N., Yamamoto,Y., Fujita,K., Isono,K., Choi,S., Ohtsubo,E., Baba,T., Wanner,B.L., Mori,H. and Horiuchi,T. TITLE Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110 JOURNAL Mol. Syst. Biol. 2, 2006 (2006) PUBMED 16738553 REFERENCE 3 (residues 1 to 1538) AUTHORS Blattner,F.R., Plunkett,G. III, Bloch,C.A., Perna,N.T., Burland,V., Riley,M., Collado-Vides,J., Glasner,J.D., Rode,C.K., Mayhew,G.F., Gregor,J., Davis,N.W., Kirkpatrick,H.A., Goeden,M.A., Rose,D.J., Mau,B. and Shao,Y. TITLE The complete genome sequence of Escherichia coli K-12 JOURNAL Science 277 (5331), 1453-1462 (1997) PUBMED 9278503 REFERENCE 4 (residues 1 to 1538) AUTHORS Arnaud,M., Berlyn,M.K.B., Blattner,F.R., Galperin,M.Y., Glasner,J.D., Horiuchi,T., Kosuge,T., Mori,H., Perna,N.T., Plunkett,G. III, Riley,M., Rudd,K.E., Serres,M.H., Thomas,G.H. and Wanner,B.L. TITLE Workshop on Annotation of Escherichia coli K-12 JOURNAL Unpublished REMARK Woods Hole, Mass., on 14-18 November 2003 (sequence corrections) REFERENCE 5 (residues 1 to 1538) AUTHORS Glasner,J.D., Perna,N.T., Plunkett,G. III, Anderson,B.D., Bockhorst,J., Hu,J.C., Riley,M., Rudd,K.E. and Serres,M.H. TITLE ASAP: Escherichia coli K-12 strain MG1655 version m56 JOURNAL Unpublished REMARK ASAP download 10 June 2004 (annotation updates) REFERENCE 6 (residues 1 to 1538) AUTHORS Hayashi,K., Morooka,N., Mori,H. and Horiuchi,T. TITLE A more accurate sequence comparison between genomes of Escherichia coli K12 W3110 and MG1655 strains JOURNAL Unpublished REMARK GenBank accessions AG613214 to AG613378 (sequence corrections) REFERENCE 7 (residues 1 to 1538) AUTHORS Perna,N.T. TITLE Escherichia coli K-12 MG1655 yqiK-rfaE intergenic region, genomic sequence correction JOURNAL Unpublished REMARK GenBank accession AY605712 (sequence corrections) REFERENCE 8 (residues 1 to 1538) AUTHORS Rudd,K.E. TITLE A manual approach to accurate translation start site annotation: an E. coli K-12 case study JOURNAL Unpublished REFERENCE 9 (residues 1 to 1538) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (08-MAR-2022) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 10 (residues 1 to 1538) AUTHORS Blattner,F.R. and Plunkett,G. III. TITLE Direct Submission JOURNAL Submitted (30-JUL-2014) Laboratory of Genetics, University of Wisconsin, 425G Henry Mall, Madison, WI 53706-1580, USA REMARK Protein update by submitter REFERENCE 11 (residues 1 to 1538) AUTHORS Blattner,F.R. and Plunkett,G. III. TITLE Direct Submission JOURNAL Submitted (15-NOV-2013) Laboratory of Genetics, University of Wisconsin, 425G Henry Mall, Madison, WI 53706-1580, USA REMARK Protein update by submitter REFERENCE 12 (residues 1 to 1538) AUTHORS Blattner,F.R. and Plunkett,G. III. TITLE Direct Submission JOURNAL Submitted (26-SEP-2013) Laboratory of Genetics, University of Wisconsin, 425G Henry Mall, Madison, WI 53706-1580, USA REMARK Sequence update by submitter REFERENCE 13 (residues 1 to 1538) AUTHORS Rudd,K.E. TITLE Direct Submission JOURNAL Submitted (06-FEB-2013) Department of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, 118 Gautier Bldg., Miami, FL 33136, USA REMARK Sequence update by submitter REFERENCE 14 (residues 1 to 1538) AUTHORS Rudd,K.E. TITLE Direct Submission JOURNAL Submitted (24-APR-2007) Department of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, 118 Gautier Bldg., Miami, FL 33136, USA REMARK Annotation update from ecogene.org as a multi-database collaboration REFERENCE 15 (residues 1 to 1538) AUTHORS Plunkett,G. III. TITLE Direct Submission JOURNAL Submitted (07-FEB-2006) Laboratory of Genetics, University of Wisconsin, 425G Henry Mall, Madison, WI 53706-1580, USA REMARK Protein updates by submitter REFERENCE 16 (residues 1 to 1538) AUTHORS Plunkett,G. III. TITLE Direct Submission JOURNAL Submitted (10-JUN-2004) Laboratory of Genetics, University of Wisconsin, 425G Henry Mall, Madison, WI 53706-1580, USA REMARK Sequence update by submitter REFERENCE 17 (residues 1 to 1538) AUTHORS Plunkett,G. III. TITLE Direct Submission JOURNAL Submitted (13-OCT-1998) Laboratory of Genetics, University of Wisconsin, 425G Henry Mall, Madison, WI 53706-1580, USA REFERENCE 18 (residues 1 to 1538) AUTHORS Blattner,F.R. and Plunkett,G. III. TITLE Direct Submission JOURNAL Submitted (02-SEP-1997) Laboratory of Genetics, University of Wisconsin, 425G Henry Mall, Madison, WI 53706-1580, USA REFERENCE 19 (residues 1 to 1538) AUTHORS Blattner,F.R. and Plunkett,G. III. TITLE Direct Submission JOURNAL Submitted (16-JAN-1997) Laboratory of Genetics, University of Wisconsin, 425G Henry Mall, Madison, WI 53706-1580, USA COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to AAC74725. Changes to proteins and annotation made on March 7, 2022. Current U00096 annotation updates are derived from EcoCyc https://ecocyc.org/. Suggestions for updates can be sent to [email protected]. These updates are being generated from a collaboration that includes EcoCyc, the University of Wisconsin, UniProtKB/Swiss-Prot, and the National Center for Biotechnology Information (NCBI). COMPLETENESS: full length. Method: conceptual translation. FEATURES Location/Qualifiers source 1..1538 /organism="Escherichia coli str. K-12 substr. MG1655" /strain="K-12" /sub_strain="MG1655" /db_xref="taxon:511145" Protein 1..1538 /product="ATP-dependent helicase Lhr" /EC_number="3.6.1.15" /calculated_mol_wt=169251 Region 27..>66 /region_name="DEAD-like_helicase_N" /note="N-terminal helicase domain of the DEAD-box helicase superfamily; cl28899" /db_xref="CDD:475120" Region 49..1538 /region_name="PRK09751" /note="putative ATP-dependent helicase Lhr; Provisional" /db_xref="CDD:137505" Site 53..59 /site_type="other" /note="putative ATP binding site [chemical binding]" /db_xref="CDD:350707" CDS 1..1538 /gene="lhr" /locus_tag="b1653" /gene_synonym="ECK1649; rhlF" /coded_by="NC_000913.3:1729087..1733703" /transl_table=11 /db_xref="UniProtKB/Swiss-Prot:P30015" /db_xref="ASAP:ABE-0005525" /db_xref="ECOCYC:EG11548" /db_xref="GeneID:946156" CONTIG join(WP_001310858.1:1..1538) ORIGIN 1 madnpdpssl lpdvfspatr dwflrafkqp tavqpqtwhv aarsehalvi aptgsgktla 61 aflyaldrlf reggedtrea hkrktsrily ispikalgtd vqrnlqiplk giaderrrrg 121 etevnlrvgi rtgdtpaqer skltrnppdi littpeslyl mltsraretl rgvetviide 181 vhavagskrg ahlalslerl dallhtsaqr iglsatvrsa sdvaaflggd rpvtvvnppa 241 mrhpqirivv pvanmddvss vasgtgedsh agregsiwpy ietgildevl rhrstivftn 301 srglaeklta rlnelyaarl qrspsiavda ahfestsgat snrvqssdvf iarshhgsvs 361 keqraiteqa lksgelrcvv atsslelgid mgavdlviqv atplsvasgl qrigraghqv 421 ggvskglffp rtrrdlvdsa vivecmfagr lenltpphnp ldvlaqqtva aaamdalqvd 481 ewysrvrraa pwkdlprrvf datldmlsgr ypsgdfsafr pklvwnretg iltarpgaql 541 lavtsggtip drgmysvllp egeekagsrr vgeldeemvy esrvndiitl gatswriqqi 601 trdqvivtpa pgrsarlpfw rgegngrpae lgemigdflh lladgaffsg tippwlaeen 661 tianiqglie eqrnatgivp gsrhlvlerc rdeigdwrii lhspygrrvh epwavaiagr 721 ihalwgadas vvasddgiva ripdtdgklp daaiflfepe kllqivreav gssalfaarf 781 recaarallm pgrtpghrtp lwqqrlrasq lleiaqgypd fpviletlre clqdvydlpa 841 lerlmrrlng geiqisdvtt ttpspfatsl lfgyvaefmy qsdaplaerr asvlsldsel 901 lrnllgqvdp gelldpqvir qveeelqrla pgrrakgeeg lfdllrelgp mtvedlaqrh 961 tgsseevasy lenllavkri fpamisgqer lacmddaarl rdalgvrlpe slpeiylhrv 1021 syplrdlflr ylrahalvta eqlahefslg iaiveeqlqq lreqglvmnl qqdiwvsdev 1081 frrlrlrslq aareatrpva attyarllle rqgvlpatdg spalfastsp gvyegvdgvm 1141 rvieqlagvg lpaslwesqi lparvrdyss emldellatg aviwsgqkkl geddglvalh 1201 lqeyaaesft paeadqanrs alqqaivavl adggawfaqq isqrirdkig esvdlsalqe 1261 alwalvwqgv itsdiwaplr altrsssnar tstrrshrar rgrpvyaqpv sprvsyntpn 1321 lagrwsllqv eplndterml alaenmldry giisrqavia enipggfpsm qtlcrsmeds 1381 grimrgrfve glggaqfaer ltidrlrdla tqatqtrhyt pvalsandpa nvwgnllpwp 1441 ahpatlvptr ragalvvvsg gklllylaqg gkkmlvwqek eellapevfh alttalrrep 1501 rlrftltevn dlpvrqtpmf tllreagfss spqgldwg