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formate dehydrogenase subunit alpha [Escherichia coli O157:H7 str.


LOCUS       NP_312847               1016 aa            linear   CON 12-FEB-2021
            Sakai].
ACCESSION   NP_312847
VERSION     NP_312847.1
DBLINK      BioProject: PRJNA226
            BioSample: SAMN01911278
DBSOURCE    REFSEQ: accession NC_002695.2
KEYWORDS    RefSeq.
SOURCE      Escherichia coli O157:H7 str. Sakai
  ORGANISM  Escherichia coli O157:H7 str. Sakai
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1
  AUTHORS   Hayashi,T., Makino,K., Ohnishi,M., Kurokawa,K., Ishii,K.,
            Yokoyama,K., Han,C.G., Ohtsubo,E., Nakayama,K., Murata,T.,
            Tanaka,M., Tobe,T., Iida,T., Takami,H., Honda,T., Sasakawa,C.,
            Ogasawara,N., Yasunaga,T., Kuhara,S., Shiba,T., Hattori,M. and
            Shinagawa,H.
  TITLE     Complete genome sequence of enterohemorrhagic Escherichia coli
            O157:H7 and genomic comparison with a laboratory strain K-12
  JOURNAL   DNA Res. 8 (1), 11-22 (2001)
   PUBMED   11258796
  REMARK    Erratum:[DNA Res 2001 Apr 27;8(2):96]
REFERENCE   2
  AUTHORS   Yokoyama,K., Makino,K., Kubota,Y., Watanabe,M., Kimura,S.,
            Yutsudo,C.H., Kurokawa,K., Ishii,K., Hattori,M., Tatsuno,I.,
            Abe,H., Yoh,M., Iida,T., Ohnishi,M., Hayashi,T., Yasunaga,T.,
            Honda,T., Sasakawa,C. and Shinagawa,H.
  TITLE     Complete nucleotide sequence of the prophage VT1-Sakai carrying the
            Shiga toxin 1 genes of the enterohemorrhagic Escherichia coli
            O157:H7 strain derived from the Sakai outbreak
  JOURNAL   Gene 258 (1-2), 127-139 (2000)
   PUBMED   11111050
REFERENCE   3
  AUTHORS   Ohnishi,M., Murata,T., Nakayama,K., Kuhara,S., Hattori,M.,
            Kurokawa,K., Yasunaga,T., Yokoyama,K., Makino,K., Shinagawa,H. and
            Hayashi,T.
  TITLE     Comparative analysis of the whole set of rRNA operons between an
            enterohemorrhagic Escherichia coli O157:H7 Sakai strain and an
            Escherichia coli K-12 strain MG1655
  JOURNAL   Syst. Appl. Microbiol. 23 (3), 315-324 (2000)
   PUBMED   11108008
REFERENCE   4
  AUTHORS   Makino,K., Yokoyama,K., Kubota,Y., Yutsudo,C.H., Kimura,S.,
            Kurokawa,K., Ishii,K., Hattori,M., Tatsuno,I., Abe,H., Iida,T.,
            Yamamoto,K., Onishi,M., Hayashi,T., Yasunaga,T., Honda,T.,
            Sasakawa,C. and Shinagawa,H.
  TITLE     Complete nucleotide sequence of the prophage VT2-Sakai carrying the
            verotoxin 2 genes of the enterohemorrhagic Escherichia coli O157:H7
            derived from the Sakai outbreak
  JOURNAL   Genes Genet. Syst. 74 (5), 227-239 (1999)
   PUBMED   10734605
REFERENCE   5  (residues 1 to 1016)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-AUG-2018) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   6  (residues 1 to 1016)
  AUTHORS   Ogura,Y., Kurokawa,K., Hayashi,T. and Hattori,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUN-2000) Contact:Yoshitoshi Ogura Kyushu University;
            31-1 Maidashi Higashi-ku, Fukuoka, Fukuoka 812-8582, Japan
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to BAB38243.
            On May 10, 2018 this sequence version replased gi: 47118301
            
            This update is obtained as follows: the Sakai genome was
            resequenced by illumina MiSeq and PacBio RS II sequencers and 78
            sites of single base error, 11 sites of insertion (10 one-base
            insertions and a 141-base insertion) and 16 sites of deletion (14
            one-base deletions, a three-base deletion and a six-base deletion)
            were corrected. Annotation was performed using DFAST
            auto-annotation system with manual curation.
            
            This work was done in collaboration with Tetsuya Hayashi, Makoto
            Ohnishi, Keisuke Nakayama (Miyazaki Medical College), Kozo Makino,
            Ken Kurokawa, Katsushi Yokoyama, Masashi Tanaka, Takeshi Honda,
            Teruo Yasunaga, Hideo Shinagawa (Osaka University), Takahiro Murata
            (Shinshu University), Chang-Gyun Han, Eiichi Ohtsubo, Toru Tobe,
            Chihiro Sasakawa (University of Tokyo), Hideto Takami (Japan Marine
            Science and Technology Center), Naotake Ogasawara (Nara Institute
            of Science and Technology), Satoru Kuhara (Kuyshu University), and
            supported by the Research for the Future Program of the Japan
            Society for the Promotion of Science.
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..1016
                     /organism="Escherichia coli O157:H7 str. Sakai"
                     /strain="Sakai"
                     /sub_strain="RIMD 0509952"
                     /serovar="O157:H7"
                     /db_xref="taxon:386585"
     Protein         1..1016
                     /product="formate dehydrogenase subunit alpha"
                     /calculated_mol_wt=112520
     Region          2..1015
                     /region_name="Molybdopterin-Binding"
                     /note="Molybdopterin-Binding (MopB) domain of the MopB
                     superfamily of proteins, a large, diverse, heterogeneous
                     superfamily of enzymes that, in general, bind
                     molybdopterin as a cofactor. The MopB domain is found in a
                     wide variety of molybdenum- and...; cl09928"
                     /db_xref="CDD:447860"
     Site            order(50,52..53,57,92,238..239)
                     /site_type="other"
                     /note="[4Fe-4S] binding site [ion binding]"
                     /db_xref="CDD:239153"
     Site            order(94,192,196,230,232,235..236,259..261,278,280,
                     409..411,414..415,447..448,556..558,562,582..584,587,617,
                     649)
                     /site_type="other"
                     /note="molybdopterin cofactor binding site"
                     /db_xref="CDD:239153"
     CDS             1..1016
                     /gene="fdoG"
                     /locus_tag="ECs_4820"
                     /coded_by="complement(NC_002695.2:4881535..4884585)"
                     /note="codon on position 196 is selenocysteine opalcodon"
                     /transl_table=11
                     /db_xref="GeneID:915079"
CONTIG      join(WP_010917870.1:1..1016)
ORIGIN      
        1 mqvsrrqffk icaggmagtt aaalgfapsv alaetrqykl lrtretrntc tycsvgcgll
       61 myslgdgakn akasifhieg dpdhpvnrga lcpkgaglvd fihsesrlkf peyrapgsdk
      121 wqqisweeaf driaklmked rdanyiaqna egvtvnrwls tgmlcasass netgyltqkf
      181 sralgmlavd nqarvuhgpt vaslaptfgr gamtnhwvdi knanlvvvmg gnaaeahpvg
      241 frwameakih ngaklividp rftrtaavad yyapirsgtd iaflsgvlly llnnekfnre
      301 yteaytnasl ivredygfed glftgydaek rkydksswty eldengfakr dttlqhprcv
      361 wnllkqhvsr ytpdvvenic gtpkdaflkv ceyiaetsah dktasflyal gwtqhsvgaq
      421 nirtmamiql llgnmgmagg gvnalrghsn iqgltdlgll sqslpgymtl psekqtdlqt
      481 yltantpkpl legqenywgn ypkffvsmmk affgdkatae nswgfdwlpk wdkgydvlqy
      541 femmkegkvn gyicqgfnpv asfpnknkvi sclsklkflv tidplntets nfwqnhgeln
      601 evdsskiqte vfrlpstcfa eengsivnsg rwlqwhwkga dapgialtdg eilsgiflrl
      661 rkmyaeqgga npdqvlnmtw nyaiphepks eevamesngk aladitdpat gavivkkgqq
      721 lssfaqlrdd gttscgcwif agswtpegnq marrdnadps glgntlgwaw awplnrrily
      781 nrasadpqgn pwdpkrqllk wdgtkwtgwd ipdysaappg sgvgpfimqq egmgrlfald
      841 kmaegpfpeh yepfetplgt nplhpnvisn paarifkdda ealgkadkfp yvgttyrlte
      901 hfhywtkhal lnailqpeqf veigeslank lgiaqgdtvk vssnrgyika kavvtkrirt
      961 lkangkdidt igipihwgye gvakkgfian tltpfvgdan tqtpefksfl vnvekv