Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]
LOCUS NP_001138185 2684 aa linear INV 26-DEC-2023 melanogaster]. ACCESSION NP_001138185 VERSION NP_001138185.2 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 DBSOURCE REFSEQ: accession NM_001144713.3 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (residues 1 to 2684) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (residues 1 to 2684) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (residues 1 to 2684) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (residues 1 to 2684) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (residues 1 to 2684) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (residues 1 to 2684) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (residues 1 to 2684) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (residues 1 to 2684) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (residues 1 to 2684) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (residues 1 to 2684) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (residues 1 to 2684) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (residues 1 to 2684) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (residues 1 to 2684) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (residues 1 to 2684) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (residues 1 to 2684) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (residues 1 to 2684) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (residues 1 to 2684) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (residues 1 to 2684) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (residues 1 to 2684) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (residues 1 to 2684) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 21 (residues 1 to 2684) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 22 (residues 1 to 2684) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 23 (residues 1 to 2684) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. The reference sequence is identical to ACL82917. On May 8, 2012 this sequence version replaced NP_001138185.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## Method: conceptual translation. FEATURES Location/Qualifiers source 1..2684 /organism="Drosophila melanogaster" /db_xref="taxon:7227" /chromosome="X" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" Protein 1..2684 /product="uncharacterized protein, isoform C" /name="CG43347 gene product from transcript CG43347-RC" /note="CG43347-PC" /calculated_mol_wt=284927 Region 1031..1146 /region_name="PR-SET_PRDM-like" /note="PR-SET domain found in PRDM (PRDI-BF1 and RIZ homology domain) family of proteins; cd10534" /db_xref="CDD:380932" Site order(1044..1045,1062,1107..1111,1113,1122..1123) /site_type="active" /db_xref="CDD:380932" Site order(1044..1045,1107..1111,1113) /site_type="other" /note="SAM binding site" /db_xref="CDD:380932" Region 1198..>1268 /region_name="NR_DBD_like" /note="DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers; cl02596" /db_xref="CDD:413390" Site order(1198,1201,1227,1230,1248,1257,1267) /site_type="other" /note="zinc binding site [ion binding]" /db_xref="CDD:143532" Region 1198..1219 /region_name="C2H2 Zn finger" /note="C2H2 Zn finger [structural motif]" /db_xref="CDD:275368" Site order(1203,1205,1207,1209..1210,1213..1214,1218,1232,1234, 1238..1239,1242..1243,1255,1264,1266,1268,1270..1271, 1274..1275,1279) /site_type="other" /note="putative nucleic acid binding site [nucleotide binding]" /db_xref="CDD:275368" Site order(1218..1219,1222,1228..1229,1231,1233,1236,1239, 1264..1265,1268) /site_type="DNA binding" /note="DNA binding site [nucleotide binding]" /db_xref="CDD:143532" Region 1227..1255 /region_name="C2H2 Zn finger" /note="C2H2 Zn finger [structural motif]" /db_xref="CDD:275368" Region 1259..1280 /region_name="C2H2 Zn finger" /note="C2H2 Zn finger [structural motif]" /db_xref="CDD:275368" Region 1292..1313 /region_name="C2H2 Zn finger" /note="C2H2 Zn finger [structural motif]" /db_xref="CDD:275368" Site order(1297,1299,1301,1303..1304,1307..1308,1312,1327,1329, 1333..1334,1337..1338,1341,1357,1359,1361,1363..1364, 1367..1368,1372) /site_type="other" /note="putative nucleic acid binding site [nucleotide binding]" /db_xref="CDD:275368" Region 1322..1342 /region_name="C2H2 Zn finger" /note="C2H2 Zn finger [structural motif]" /db_xref="CDD:275368" Region 1350..1373 /region_name="C2H2 Zn finger" /note="C2H2 Zn finger [structural motif]" /db_xref="CDD:275368" CDS 1..2684 /gene="CG43347" /locus_tag="Dmel_CG43347" /old_locus_tag="Dmel_CG15295" /old_locus_tag="Dmel_CG9817" /gene_synonym="BcDNA:RH11383; CG15295; CG9817; Dmel\CG43347" /coded_by="NM_001144713.3:347..8401" /db_xref="FLYBASE:FBpp0297865" /db_xref="GeneID:31991" /db_xref="FLYBASE:FBgn0263072" ORIGIN 1 mkkkqkqkqq qqqqqrqska pseaeseadr pgsnssstsn nkhsppaast ttttkrrqvs 61 ssnnntsnhk nnskrcsrss ssssscssss ssssnasvgs smsktssgnp aaagatnaan 121 aadfsafdfn dssdnsdtpl vprppflsra aataaaaaaa aaalsisnns nnsagsagql 181 phstssssnn nnnnnnnnga nsvnsnannn nyghsssssq ssmdeeeedd eeedeeeeee 241 qdvsqqqqqq qqlaaeqqqr aaaaaavvaa avsalhngnk qqhynnnnnn nnngntksrd 301 radhhlqsqq qqehdddedd deeegeeded eddeeqhqeq qqqhqgnghd ltptdlrhvm 361 pasnnlqqqh tqqqqepaay ddegeeeded dddedevass hldsratlss ghlnsaaaae 421 ssglhmsvaa aaaaaaaaaa avsaaklnaq leqqqsanal dmasgssatp iappppssll 481 ggnsntsfst nnnsnhalss thgslgpggq gtncsndlma tgggnsrggs slslginsss 541 aaalqhqhqq qqqqqqhggg sggssaaser rkyrhqnysk niyigtknae kwehmrtrlq 601 fkndvefvay llnladndtd rlnnlpppsp antptkgfdg nfklepnlsa kdfatpaess 661 ingngsgnts gngngdsasa asipmvtptp pqrkrykkrv qftsetlngf agktkgsgsg 721 gagagfsyak skkqeakaat aalkasaaaa aaaaassalp evldcriaek ikseleansk 781 eslpnalclk kaaaaaaaaa aaaaavaaaa ngseeedede dqpphphllp vlppadavdg 841 itasngqagn fhvrsksqgs kksqaakaaa aammppnsyd ehddepgagl ggndeddddd 901 eeldeealar emkmeqnfve eedehdiafr shqscrecsi ahdhklcplr nacgnvtdav 961 dlgewierrn lealaklkad aqrqakrasg rqrhedddme dmedmdmdmd essqlselet 1021 kplitfaeas vpaefelhnv epnvtgvfar tevraftklg pligqpvqtg evregsdmkw 1081 ifemceagad ksyllccdnp nasnwlrfvr papsyeernv nlvsidrqay fvscrdlrng 1141 mellywsddc ntmwrkkhte ktncggcnlk fehplyyrth csvfhdpsms ltirkyhckv 1201 cgepvlgkdn imkhaaekhd gkgayqcqfc skfflrlnyl emhrtygcas npnrsrpvcd 1261 fcgrkfcqpq klkahikrmh sdmaevlrdf qcklcskllg sraalqrhsk evhsrnstvv 1321 scprcqklfq nrsnlkihml thsgvrpfkc aepecnaaft tkqclqfhyk kvhnytqeqm 1381 pkiersvayt fdaysggmkv dflgkqtata tpasaasaqa qprpnaavvs pssfteqapr 1441 rrrksledqs smlsgslqsd aefsddnlfe aikksgksik dlcrnepnls llsskissif 1501 gdkvpsatas lsasvsavas sgarkrkrkk epvvpaqqql hlhqqqqqqq qqqqqsqhqq 1561 qhqqqhaqql qhqqlqqqha qqhqqqqhhl hqqhqqlhhd pqqqhpqyhp hqlhahalph 1621 qqqqqqqqqq qqqqqlhgdp ddeevenarl eqvrrkqnaq lslvesfltt taqrlsaqqq 1681 vqqvvaaaaa vsamagaged paklghmmgh mgvgvgvgmd eeedddeddd dggggggggg 1741 gsavqhhphv hahqahhshv hahahphhah shahphqhpa sqgagqqdyr haaamnaalg 1801 qnlvvskgsk kwiqevqdss dvggegaggg gggpgdsggp ggggacgqla ggsgpgpdlg 1861 favpptavde hskllgqnrd flarlmssas ashahahaha hahahqphqt hqqhqhsahs 1921 reedenssfl dvvesnnnaa aaaaaaaals hygggagsgs agggsggqtp tgpatgggsv 1981 aggdepqmqm nslahsqsfm ssfynnanar vggvgggvvg vgvgggsssa smlveaalns 2041 vgnmidsess dlkvptdnhi nsdspmsahv dpesqrfgag saggaggggg ggggggssgg 2101 ssggangsgi gggmdnlene lkmmknlgsf pmqipplpmf qgacnispsa stptnpqsnq 2161 nqndvdvdag stprpqhpds dgfssshhrt ppspppispg rdyggmfgag nggggpgsns 2221 tpagsssggg ggggggaggg gansmsassp lpalqpqrrn assvgstype helispassp 2281 siprynfngd mmrhkravqe qehqerqrqn isrhnqmssd eensimpqns agqdmrmkfp 2341 qsqidlmysk yesmasnlky nsqdldspae yrqggagngg naaasaaaaa aaaasaandl 2401 sdlqgldmss rsnaassnyh hnfqlpssry hhhiydilsd reqqsqqaqq aggavvgggg 2461 gggagaasvv hqqehghgqh hamqqhqqsa aamhnmlseq lgeqehdqtt svdlsrtany 2521 vvssppqlpy nhpthhdmlr masldltpnt anmavgnnrs flssqmqhqs reslehhrll 2581 stveqhrila asnaadqhrl lvdptahllm eqnnrllgta dqsrllgesa aaaaqnrhma 2641 rsfgayhqva ssnyhpgvrp ppvlpsanhh asnpsnyhpf payy