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LOCUS NM_167114 5164 bp mRNA linear INV 26-DEC-2023 mRNA. ACCESSION NM_167114 VERSION NM_167114.2 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 5164) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 5164) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 5164) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 5164) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 5164) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 5164) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 5164) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 5164) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 5164) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 5164) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 5164) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 5164) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 5164) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 5164) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 5164) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 5164) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 5164) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 5164) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 5164) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 5164) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 21 (bases 1 to 5164) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 22 (bases 1 to 5164) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 23 (bases 1 to 5164) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NC_004354). On Nov 2, 2005 this sequence version replaced NM_167114.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..5164 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="X" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..5164 /gene="Sxl" /locus_tag="Dmel_CG43770" /old_locus_tag="Dmel_CG14425" /old_locus_tag="Dmel_CG18350" /gene_synonym="CG14425; CG18350; CG33070; CG43770; Dm-Sxl; Dmel\CG43770; DmSxl; dSXL; Fl; fs(1)K1274; fs(1)M106; l(1)6Fa; melSxl; Mex156; ORF2; Su(da); Sx1; sxl; SxL; SXL; Sxl-1 Sxl-2; Sxl-Pe; SxlPe; SxlPm" /note="Sex lethal" /map="6F3-6F5" /db_xref="FLYBASE:FBgn0264270" /db_xref="GeneID:3772180" CDS 426..1526 /gene="Sxl" /locus_tag="Dmel_CG43770" /old_locus_tag="Dmel_CG14425" /old_locus_tag="Dmel_CG18350" /gene_synonym="CG14425; CG18350; CG33070; CG43770; Dm-Sxl; Dmel\CG43770; DmSxl; dSXL; Fl; fs(1)K1274; fs(1)M106; l(1)6Fa; melSxl; Mex156; ORF2; Su(da); Sx1; sxl; SxL; SXL; Sxl-1 Sxl-2; Sxl-Pe; SxlPe; SxlPm" /note="CG43770 gene product from transcript CG43770-RH; CG43770-PH; Sxl-PH; Sex-kethal; sex-lethal; Sex lethal; female lethal; sexlethal" /codon_start=1 /product="Sex lethal, isoform H" /protein_id="NP_727164.2" /db_xref="FLYBASE:FBpp0303693" /db_xref="GeneID:3772180" /db_xref="FLYBASE:FBgn0264270" /translation="MYGNNNPGSNNNNGGYPPYGYNNKSSGGRGFGMSHSLPSGMDTE FSFPSSSSRRGYNDFPGCGGSGGNGGSANNLGGGNMCHLPPMASNNSLNNLCGLSLGS GGSDDLMNDPRASNTNLIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGYSFGY AFVDFTSEMDSQRAIKVLNGITVRNKRLKVSYARPGGESIKDTNLYVTNLPRTITDDQ LDTIFGKYGSIVQKNILRDKLTGRPRGVAFVRYNKREEAQEAISALNNVIPEGGSQPL SVRLAEEHGKAKAAHFMSQMGVVPANVPPPPPQPPAHMAAAFNMMHRDGAMEKLRSLF DAICDAIFGLDSENFADLLDGLYRRKYHYPYL" misc_feature 471..1316 /gene="Sxl" /locus_tag="Dmel_CG43770" /old_locus_tag="Dmel_CG14425" /old_locus_tag="Dmel_CG18350" /gene_synonym="CG14425; CG18350; CG33070; CG43770; Dm-Sxl; Dmel\CG43770; DmSxl; dSXL; Fl; fs(1)K1274; fs(1)M106; l(1)6Fa; melSxl; Mex156; ORF2; Su(da); Sx1; sxl; SxL; SXL; Sxl-1 Sxl-2; Sxl-Pe; SxlPe; SxlPm" /note="sex-lethal family splicing factor; Region: sex-lethal; TIGR01659" /db_xref="CDD:273740" ORIGIN 1 acactgcttt gttgttgccg aagaaggaaa gtcgcgcagt gaattttttt ctgcgcgcct 61 acaagaacag ctataataag cacacactta aaaaaaaccc cataggactt aagagaggaa 121 agcacagtga gcgtgcacac atgtaaaaag agaaagagag caacagcaat tttagtacaa 181 cacaagaaag ttgaacagag gcagaagaga agtaacagga aaacaataac aacgacagca 241 gcaggccagc tgagagcgct gagcgccaaa acaattgaag agatcgattg aatctcgatc 301 atcgttctta acctcaagtc aactgcaact cacctcatca tccttttcct gtaaaaccga 361 aactcacctt cgatcgaggg tgtaactttt gttgattcga aaaacacact cccaactctc 421 aggatatgta cggcaacaat aatccgggta gtaacaataa taatggtggt tatcccccat 481 atggctacaa caacaagtcg agtggtgggc gtggatttgg gatgtcccat tctctgccat 541 ccggaatgga tacagaattt tcatttccaa gttcatcgtc gcgtcgtggt tacaatgatt 601 tccccggctg cggcggcagc ggcggaaatg gtgggagtgc caacaattta gggggcggca 661 acatgtgcca cctgccgccg atggccagca acaactcgct gaataatctc tgcggattgt 721 cgctgggcag cggtggtagt gatgatctca tgaacgatcc tcgggcaagc aacaccaacc 781 tgattgtcaa ctacttgccc caggacatga ccgatcgcga gctgtacgcc ctattcagag 841 ccattggacc catcaacacg tgcagaatca tgcgagacta taagactggc tacagttttg 901 gttatgcttt cgtggacttc acatcggaaa tggactcgca gcgtgctatt aaagtgctga 961 atggcatcac agtgcgcaac aagcggctta aggtttccta tgcacgtccc ggcggagaat 1021 cgatcaagga caccaatctg tatgtgacca atctgccgcg taccataacc gacgatcagc 1081 tggacacgat cttcggcaag tacggttcca ttgtgcagaa gaacatcttg cgtgacaagc 1141 tcacaggtcg tcctcgtggt gtggcctttg ttcggtacaa caagcgtgag gaggcccagg 1201 aggccatttc ggcgctgaac aacgtaatac ccgagggcgg atcacagccg ctgtccgtcc 1261 ggttggctga ggagcatggc aaggcgaagg cggcccactt tatgtcgcag atgggcgtgg 1321 ttccagcaaa tgtaccaccg ccgccaccac aaccgccagc acatatggcc gccgcattca 1381 acatgatgca cagagacgga gctatggaaa aattacgctc attattcgat gctatatgcg 1441 atgctatctt tggtctcgat agcgaaaact ttgccgattt gcttgacgga ttgtaccgta 1501 ggaagtacca ttatccttac ttataattga caccgcaaca gcagcagcaa ctactacaac 1561 atcagcagca ggcgttgggc ttcaccagta gctccaataa tagtattggc aatggtaatg 1621 gcaacgacaa caacatgcta ctttaccacc agcaatacca tcaacaacaa acacaacaac 1681 aacgcctggg caatgttgct gctcacaata taagtccaaa tggaagcaat aataacatta 1741 acacgtcgaa caccaataac attaacttca atacaatacg tcagaatgga gttgctgctc 1801 ttcactatct tcaggaacaa ttgcaattgc aacaaccgca ggatcaacaa tcacagcaac 1861 agcagccatt gactatgcca tcttcgccgc cgtttcaaca acaatcacgc caatcacacc 1921 acaatggcag cagtagcact ctgggcaatc agttgcttgc cataagcaac aacaatagct 1981 tcaataataa ttccaatcaa tccaatagtt ttactggcaa ttacagcaac ggtagcgctt 2041 ttaccagtaa cggtgccatt agcggtagca actttcccaa caatcccaca agcagtggga 2101 acttcaccaa caactcaaca aacagcaacc ccacaaacag tggacacttt gccagtaatt 2161 tggctggcag cagcaacttt accaaccatc tttctggcag caacaattac accaacagca 2221 acggaaattt caccagtaat gcagctagca gtagcaactt ctccaacaat gcagctagca 2281 gcaccaatta cagcaagaac tgcagcagcg gcgtcgttgg aaacagcgat cccgacagtt 2341 gtagcagaaa acacaccacc aacactaata atcaccacac ttcgccgcag cacgacttca 2401 gttttaatat gtcaacgact gaacaagaac tgcatcagca gacactcaag ttgcagcagc 2461 tgcatctgaa caacagcttc aacaacacca cagcagctgc aacaacttca gcggctgcat 2521 caacttccac ttcaacaacg gcaacggcat catccacaaa ctccgcaaat gtcggatttt 2581 tatggcgtac ataaccagag agttgagaag cgtatgatga aggcaatctt caaattaaag 2641 attatatata aaaagcttat atatataaaa ctatgaatac cttatattga tcatcgtagt 2701 atcagcattc atcgaaacca tatacaacaa ctgaaacttt tatgttctca aaccacaaga 2761 attaatttac tacttttttt ttttttgtat gttcctcact ttaacccata tgttgtagtt 2821 ggttttttgt gctttttttt tgggaggaat cctgttgtaa ctagctctaa ggcaagacac 2881 gtatatgtat acaaatcata aataattata tatatataca tatatatata tatatatata 2941 aagaatgaaa aatcgacgaa gatttttttt ttgcttaaac ttagagaaaa aacctatgag 3001 aaatacattt ttttgtcaca tatttataac gtataatcat aacgaaaacg acaaaatata 3061 ttatacaaac acacatatat atctatacta tataacatac ttataggcgt gatgaaataa 3121 gctccgattg tttttttttt ttctgtctga aactgatttt tttggcgcga actatgccgc 3181 aacaatgtac acggtcatcg tgtatgttta tagctgaagt taatccagat atatgaatat 3241 atatattatt ttttttcata atttataaat ccaatttttt tgtctatatt atacgtaacg 3301 aaacggctaa aatgactgga catgctcaag ttttcaggct gtttattcat aacatataaa 3361 acgaaaacat acaacttagc tagcagtatg cttgagtagg cgaaggagaa agagaatcag 3421 acaaaattac aatacaaacc caattttttt catagctata atgaatatgt tttttttttt 3481 ttaataagta taaaaacttt tcttgaaatc catttttttt tattagttta attaacgaaa 3541 caacttgagc atgtaacagc aagaaaaaca aaagtaacat tcaaaaagcg actaacaaag 3601 aaacgtgata aatagcccgt caaaacgaaa atcagaggaa accgaatggg aaaggtaaaa 3661 gaaaaaaata gagacacaat cgaaagtaac gaaagagaaa cacgtcaaat cacaggagtg 3721 acttggtttg attgcctaaa aaacgcatgg ataacgtttt aacttttaat ttgcctaaca 3781 cacttttcga aattctaaat tggccagtca ctccttctgc aggcaaaaaa tattttttcg 3841 gtgtaggtac ataagtaaat gaaacagaaa cattattttg ttactacaat atatgcgatg 3901 atcctttttt gcaaaattct atcaatactt ttatgaatat acttttataa tcaaacaaaa 3961 aattgtgaaa aaattttaat ttgttaaaaa acagaagaaa aaatcagaat ttcaatttta 4021 ttttattatt ttattaccat ggcttaaaac aaatcataca aggaaataag aaaaaccatt 4081 atttaaggaa acttaataaa cattttcgac acaaaccaca ctacccctga gttttctttt 4141 ttatttaaac ctatgattaa gattaaaaaa tatttcgttt tcccccagtt tgtgtgacac 4201 ataagtcaac gaattaagag taacaaacaa caattagatt taagcgaaac atgcagaagg 4261 aaaagttaag ctgcagacac acagtaaaca catacagctt ggttgtgctg aatactaaat 4321 ataacgattc aaaaacatta acaaattaga tccgacagtg cgtacgtacg tagcgaatgc 4381 aaacaattgt acacaaaagc gaaagcgaat atttgaatca ctatgtaagc gacattcatt 4441 ctaaagccat ccagtcggga aggcggcgtc gaactcactt aaatcgaatg caaatagtct 4501 caaccaaagt agccttagtg agtaagcgga tatatacata acgaatatcg gattaatcgg 4561 aaggagaact catacaatgc atatggcacc ttagcatgct gtgtcgattg tctcgtgtaa 4621 ctagattaag tcaatgcaaa ccaaaagtaa atattaatta tttttttttt cttggatagc 4681 gaaatgagaa aatatttttt gtgactattt tttgagcatg tgacgtaagg caaatcataa 4741 acgaacttga tttttttttt aatgagacag tttttttctt gtaattcttt ttagaacatt 4801 tttttcttta ctcataagaa gccaagctaa ttttgttgta ataccgagac cgaaatgtag 4861 gcgcagcaac tgaatagaat ttttttttgg taattttaat aactaacgtt gtagaacaag 4921 gtaacctcac agaaaaccta atcgcaaata catttaaaat gttgttcaat aataacttaa 4981 agcatgaaaa gtgttaagta acggaatata tattatacat ttttttatat cgaagtaaat 5041 gtgtctagaa ggtaaaataa tctttttata aagaaaaaaa caaaatacca gaaatatgca 5101 tacaattttt ttttctagca taagacaaag cgttttttat ataaacatat tatacaagaa 5161 aacc