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LOCUS NM_167008 7112 bp mRNA linear INV 26-DEC-2023 variant B, mRNA. ACCESSION NM_167008 VERSION NM_167008.2 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 7112) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 7112) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 7112) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 7112) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 7112) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 7112) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 7112) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 7112) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 7112) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 7112) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 7112) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 7112) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 7112) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 7112) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 7112) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 7112) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 7112) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 7112) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 7112) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 7112) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 21 (bases 1 to 7112) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 22 (bases 1 to 7112) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 23 (bases 1 to 7112) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NC_004354). On Jul 15, 2014 this sequence version replaced NM_167008.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..7112 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="X" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..7112 /gene="norpA" /locus_tag="Dmel_CG3620" /gene_synonym="anon-EST:Posey221; CdkA; CG3620; DIP2; Dmel\CG3620; MRE18; nofC; NorpA; NORPA; PI-PLC; PLC; PLC-beta; PLCbeta; rof; x12; x13; x16; x24" /note="no receptor potential A" /map="4B6-4C1" /db_xref="FLYBASE:FBgn0262738" /db_xref="GeneID:31376" CDS 980..4267 /gene="norpA" /locus_tag="Dmel_CG3620" /gene_synonym="anon-EST:Posey221; CdkA; CG3620; DIP2; Dmel\CG3620; MRE18; nofC; NorpA; NORPA; PI-PLC; PLC; PLC-beta; PLCbeta; rof; x12; x13; x16; x24" /EC_number="3.1.4.-" /EC_number="3.1.4.11" /note="CG3620 gene product from transcript CG3620-RB; CG3620-PB; norpA-PB; no-receptor-potential-A; norp A; mRNA-like ncRNA in embryogenesis 18; phospholipase cbeta; phospholipase C; No receptor potential A; no receptor potential; eye-specific PLC; phospholipase C-beta; phospholipase C[[beta]]; phospholipase-C; no-receptor-potential A; no-receptor potential A; no receptor potentials A" /codon_start=1 /product="no receptor potential A, isoform B" /protein_id="NP_726925.1" /db_xref="FLYBASE:FBpp0070618" /db_xref="GeneID:31376" /db_xref="FLYBASE:FBgn0262738" /translation="MTKKYEFDWIIPVPPELTTGCVFDRWFENEKETKENDFERDALF KVDEYGFFLYWKSEGRDGDVIELCQVSDIRAGGTPKDPKILDKVTKKNGTNIPELDKR SLTICSNTDYINITYHHVICPDAATAKSWQKNLRLITHNNRATNVCPRVNLMKHWMRL SYCVEKSGKIPVKTLAKTFASGKTEKLVYTCIKDAGLPDDKNATMTKEQFTFDKFYAL YHKVCPRNDIEELFTSITKGKQDFISLEQFIQFMNDKQRDPRMNEILYPLYEEKRCTE IINDYELDEEKKKNVQMSLDGFKRYLMSDENAPVFLDRLDFYMEMDQPLAHYYINSSH NTYLSGRQIGGKSSVEMYRQTLLAGCRCVELDCWNGKGEDEEPIVTHGHAYCTEILFK DCIQAIADCAFVSSEYPVILSFENHCNRAQQYKLAKYCDDFFGDLLLKEPLPDHPLDP GLPLPPPCKLKRKILIKNKRMKPEVEKVELELWLKGELKTDDDPEEDASAGKPPEAAA APAPAPEAAAAAEGAAEGGGGAEAEAAAANYSGSTTNVHPWLSSMVNYAQPIKFQGFD KAIEKNIAHNMSSFAESAGMNYLKQSSIDFVNYNKRQMSRIYPKGTRADSSNYMPQVF WNAGCQMVSLNFQSSDLPMQLNQGKFEYNGGCGYLLKPDFMRRADKDFDPFADAPVDG VIAAQCSVKVIAGQFLSDKKVGTYVEVDMFGLPSDTVKKEFRTRLVANNGLNPVYNED PFVFRKVVLPDLAVLRFGVYEESGKILGQRILPLDGLQAGYRHVSLRTEANFPMSLPM LFVNIELKIYVPDGFEDFMAMLSDPRGFAGAAKQQNEQMKALGIEEQSGGAARDAGKA KEEEKKEPPLVFEPVTLESLRQEKGFQKVGKKQIKELDTLRKKHAKERTSVQKTQNAA IDKLIKGKSKDDIRNDANIKNSINDQTKQWTDMIARHRKEEWDMLRQHVQDSQDAMKA LMLTVQAAQIKQLEDRHARDIKDLNAKQAKMSADTAKEVQNDKTLKTKNEKDRRLREK RQNNVKRFMEEKKQIGVKQGRAMEKLKLAHSKQIEEFSTDVQKLMDMYKIEEEAYKTQ GKTEFYA" misc_feature 1028..1426 /gene="norpA" /locus_tag="Dmel_CG3620" /gene_synonym="anon-EST:Posey221; CdkA; CG3620; DIP2; Dmel\CG3620; MRE18; nofC; NorpA; NORPA; PI-PLC; PLC; PLC-beta; PLCbeta; rof; x12; x13; x16; x24" /note="Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain; Region: PH_PLC_beta; cd13361" /db_xref="CDD:270167" misc_feature order(1043..1045,1049..1051,1100..1102,1151..1153, 1346..1348) /gene="norpA" /locus_tag="Dmel_CG3620" /gene_synonym="anon-EST:Posey221; CdkA; CG3620; DIP2; Dmel\CG3620; MRE18; nofC; NorpA; NORPA; PI-PLC; PLC; PLC-beta; PLCbeta; rof; x12; x13; x16; x24" /note="Rac1 binding site [polypeptide binding]; other site" /db_xref="CDD:270167" misc_feature order(1052..1054,1058..1060,1091..1093,1097..1099, 1103..1105,1148..1153) /gene="norpA" /locus_tag="Dmel_CG3620" /gene_synonym="anon-EST:Posey221; CdkA; CG3620; DIP2; Dmel\CG3620; MRE18; nofC; NorpA; NORPA; PI-PLC; PLC; PLC-beta; PLCbeta; rof; x12; x13; x16; x24" /note="putative phosphoinositide binding site [chemical binding]; other site" /db_xref="CDD:270167" misc_feature 1439..1897 /gene="norpA" /locus_tag="Dmel_CG3620" /gene_synonym="anon-EST:Posey221; CdkA; CG3620; DIP2; Dmel\CG3620; MRE18; nofC; NorpA; NORPA; PI-PLC; PLC; PLC-beta; PLCbeta; rof; x12; x13; x16; x24" /note="EF-hand motif found in Drosophila melanogaster No receptor potential A protein (NorpA) and similar proteins; Region: EFh_NorpA_like; cd16212" /db_xref="CDD:320042" misc_feature 1439..1528 /gene="norpA" /locus_tag="Dmel_CG3620" /gene_synonym="anon-EST:Posey221; CdkA; CG3620; DIP2; Dmel\CG3620; MRE18; nofC; NorpA; NORPA; PI-PLC; PLC; PLC-beta; PLCbeta; rof; x12; x13; x16; x24" /note="EF-hand motif [structural motif]; Region: EF-hand motif" /db_xref="CDD:320042" misc_feature 1544..1633 /gene="norpA" /locus_tag="Dmel_CG3620" /gene_synonym="anon-EST:Posey221; CdkA; CG3620; DIP2; Dmel\CG3620; MRE18; nofC; NorpA; NORPA; PI-PLC; PLC; PLC-beta; PLCbeta; rof; x12; x13; x16; x24" /note="EF-hand motif [structural motif]; Region: EF-hand motif" /db_xref="CDD:320042" misc_feature 1658..1747 /gene="norpA" /locus_tag="Dmel_CG3620" /gene_synonym="anon-EST:Posey221; CdkA; CG3620; DIP2; Dmel\CG3620; MRE18; nofC; NorpA; NORPA; PI-PLC; PLC; PLC-beta; PLCbeta; rof; x12; x13; x16; x24" /note="EF-hand motif [structural motif]; Region: EF-hand motif" /db_xref="CDD:320042" misc_feature 1796..1897 /gene="norpA" /locus_tag="Dmel_CG3620" /gene_synonym="anon-EST:Posey221; CdkA; CG3620; DIP2; Dmel\CG3620; MRE18; nofC; NorpA; NORPA; PI-PLC; PLC; PLC-beta; PLCbeta; rof; x12; x13; x16; x24" /note="EF-hand motif [structural motif]; Region: EF-hand motif" /db_xref="CDD:320042" misc_feature 1931..2938 /gene="norpA" /locus_tag="Dmel_CG3620" /gene_synonym="anon-EST:Posey221; CdkA; CG3620; DIP2; Dmel\CG3620; MRE18; nofC; NorpA; NORPA; PI-PLC; PLC; PLC-beta; PLCbeta; rof; x12; x13; x16; x24" /note="Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta; Region: PI-PLCc_beta; cd08591" /db_xref="CDD:176533" misc_feature order(1979..1984,2069..2071,2075..2077,2120..2122, 2222..2224,2378..2380,2384..2386,2714..2716,2795..2797, 2801..2803) /gene="norpA" /locus_tag="Dmel_CG3620" /gene_synonym="anon-EST:Posey221; CdkA; CG3620; DIP2; Dmel\CG3620; MRE18; nofC; NorpA; NORPA; PI-PLC; PLC; PLC-beta; PLCbeta; rof; x12; x13; x16; x24" /note="putative active site [active]" /db_xref="CDD:176533" misc_feature order(1979..1981,2120..2122) /gene="norpA" /locus_tag="Dmel_CG3620" /gene_synonym="anon-EST:Posey221; CdkA; CG3620; DIP2; Dmel\CG3620; MRE18; nofC; NorpA; NORPA; PI-PLC; PLC; PLC-beta; PLCbeta; rof; x12; x13; x16; x24" /note="catalytic site [active]" /db_xref="CDD:176533" misc_feature order(1982..1984,2069..2071,2075..2077,2222..2224) /gene="norpA" /locus_tag="Dmel_CG3620" /gene_synonym="anon-EST:Posey221; CdkA; CG3620; DIP2; Dmel\CG3620; MRE18; nofC; NorpA; NORPA; PI-PLC; PLC; PLC-beta; PLCbeta; rof; x12; x13; x16; x24" /note="Ca binding site [ion binding]; other site" /db_xref="CDD:176533" misc_feature 3044..3397 /gene="norpA" /locus_tag="Dmel_CG3620" /gene_synonym="anon-EST:Posey221; CdkA; CG3620; DIP2; Dmel\CG3620; MRE18; nofC; NorpA; NORPA; PI-PLC; PLC; PLC-beta; PLCbeta; rof; x12; x13; x16; x24" /note="C2 domain present in Phosphoinositide-specific phospholipases C (PLC); Region: C2_PLC_like; cd00275" /db_xref="CDD:175974" misc_feature order(3089..3091,3167..3169,3260..3262,3266..3268, 3272..3274,3278..3280) /gene="norpA" /locus_tag="Dmel_CG3620" /gene_synonym="anon-EST:Posey221; CdkA; CG3620; DIP2; Dmel\CG3620; MRE18; nofC; NorpA; NORPA; PI-PLC; PLC; PLC-beta; PLCbeta; rof; x12; x13; x16; x24" /note="Ca2+ binding pocket [ion binding]; other site" /db_xref="CDD:175974" misc_feature 3572..3706 /gene="norpA" /locus_tag="Dmel_CG3620" /gene_synonym="anon-EST:Posey221; CdkA; CG3620; DIP2; Dmel\CG3620; MRE18; nofC; NorpA; NORPA; PI-PLC; PLC; PLC-beta; PLCbeta; rof; x12; x13; x16; x24" /note="Protein of unknown function (DUF1154); Region: DUF1154; pfam06631" /db_xref="CDD:461969" misc_feature 3833..4198 /gene="norpA" /locus_tag="Dmel_CG3620" /gene_synonym="anon-EST:Posey221; CdkA; CG3620; DIP2; Dmel\CG3620; MRE18; nofC; NorpA; NORPA; PI-PLC; PLC; PLC-beta; PLCbeta; rof; x12; x13; x16; x24" /note="PLC-beta C terminal; Region: PLC-beta_C; pfam08703" /db_xref="CDD:462571" ORIGIN 1 gcgaaacgga cgcgaatttt catttgtgct gcggaaacca acaacaacag acaacaaata 61 aaaacaaacg aaaaacaaaa cggtcaaaat tccgtgtaaa aaaactgaag ccttggaaaa 121 atagaacgaa aaacatagac gcactaaaag ctcagtgaag tcctttgtgg gcgaaaccgt 181 ataataaaat aaatcacagc cacacgcgct ttctgtaact ccttttcgcc ttgccctgct 241 cttgttttcc cttttaaata ttttttttac gagttggttt cccgagaatt tcccatactc 301 gcgcgtggta aacaagactc attttttttt tacagtgttt gttttttgaa agtgcagaga 361 agctgacaag aaagagataa caacataaaa acagaaacag ccaaagagtg gcaacaacaa 421 acaaaccaac caaacggaat caaagtcaaa caaacgcgaa cgcgaaggaa gcttcaaaag 481 agagacaaga gcgtgaaaag gaggtggaga ggagctgcgg agaatctaag ttcagtacat 541 tgtcgtgctg ccatcaaact aaactaaatg ttgcgctgcg tcgaggattt taaataaaag 601 ggaacctgcc gctcggaagt tgtggcagaa gtgcagcaag tgctgccggg ccaagttcaa 661 ttagccggaa aacggaccat gtgatctgct ataaatgcga ttgtatatac acacacacac 721 ataatccgtt gggagcagcg atagataggg ccagtatata atatgtccgg aaattaagtg 781 gactgtagaa aaagagagag agagagagcg agagagagag tgagagagag caagcgacgg 841 gggacagatc ttgatctggc ttagatatat atcgcatgtg cagggcaacg gaaacggaag 901 cgtcagcggc aacggaaaca gcaacggaag tggaaacgga aacggaagtg gctaagctaa 961 cgtcacacag tctgcaataa tgaccaagaa gtacgagttc gattggatca ttccggttcc 1021 gccggaattg accacgggct gcgtttttga tcgctggttc gaaaacgaaa aggagacaaa 1081 ggagaatgac tttgagcgtg atgccctctt caaggtcgat gaatacggat tttttctgta 1141 ctggaaaagc gagggcaggg atggcgatgt catagagctc tgccaagtga gcgacattcg 1201 tgcgggcgga acaccaaagg atccgaagat acttgataag gtgacgaaga agaacggcac 1261 caatataccg gaactggata agcgatccct gacgatctgt tcgaacacgg actatatcaa 1321 tataacatat caccatgtta tttgtccaga tgcggcaaca gccaagagct ggcaaaagaa 1381 cttgcgtctc atcacgcata ataaccgcgc cacgaatgtg tgcccgcgcg tcaacctgat 1441 gaagcattgg atgcgattga gttactgcgt agagaagagt ggaaaaattc cggttaaaac 1501 gctggccaaa acctttgcat ccggcaaaac ggagaaattg gtgtacacgt gcataaagga 1561 tgccggtctg cccgatgata aaaacgcaac gatgaccaag gagcagttca ccttcgacaa 1621 gttctacgcc ttgtaccaca aggtgtgtcc ccgaaacgac attgaggagc tcttcacctc 1681 catcaccaag ggcaagcagg acttcattag cttggagcag tttattcagt ttatgaacga 1741 caaacagcgc gatccgcgga tgaacgaaat tctgtaccct ctctacgagg agaaacgttg 1801 cacggagatc atcaacgatt acgagctaga tgaggagaaa aagaagaacg ttcaaatgtc 1861 gttggacgga tttaagcgct atctaatgtc cgacgaaaac gcacctgtat tcctggaccg 1921 gctggatttc tacatggaaa tggatcagcc actggcccat tactatatca acagctcgca 1981 taatacctac ctatccggtc gtcagatcgg cggcaaaagt tccgtggaaa tgtaccgaca 2041 gacactcttg gcaggttgtc gctgtgtgga gctggattgc tggaacggaa agggtgagga 2101 cgaggagcca attgtcaccc acggtcacgc ctactgcact gaaatcctct ttaaggactg 2161 catccaggcg attgcggatt gcgccttcgt gtcctccgag tatccggtaa tcctgtcctt 2221 cgaaaaccac tgcaaccgcg cccagcaata caagttggcc aaatactgtg atgacttctt 2281 cggcgatctg ctgctaaagg agccgctacc agatcatccg ctggatccgg gccttccgtt 2341 gccgccaccc tgcaaactga agcgtaagat cctcatcaag aacaagcgaa tgaagccaga 2401 agtggaaaag gtcgagttgg agctctggct gaagggcgaa ctcaaaacgg atgacgatcc 2461 ggaagaggac gccagtgcgg gcaagccgcc agaggcagcc gccgcacccg cacccgcccc 2521 ggaagcagcc gccgccgccg aaggagcggc cgaggggggc ggtggagcgg aggccgaagc 2581 cgccgctgcc aactacagcg gctccaccac caacgtgcat ccgtggctct cctccatggt 2641 caattacgcg cagcccatca agttccaggg cttcgacaag gcaatcgaaa agaatattgc 2701 ccacaacatg tcctcgtttg cggaatcggc gggcatgaac tacttgaagc agagctccat 2761 cgactttgtc aattacaaca agcgtcagat gtcgcgaatt tatccgaagg gcacacgagc 2821 ggactcctca aactatatgc cgcaggtgtt ctggaacgcc ggctgccaga tggtctcact 2881 caatttccag agctccgatt tacccatgca actcaaccag ggcaagttcg agtataatgg 2941 cggctgtggc tatctactaa aaccggattt catgcgtcga gccgacaagg attttgatcc 3001 gtttgccgat gcgccggtgg acggtgtgat tgcggcccag tgttccgtta aagtgattgc 3061 cggccaattc ttgtccgaca agaaagtggg cacctatgtg gaggtggaca tgtttggatt 3121 gccctcggac acggtgaaaa aagagtttcg aacgcgtttg gtcgccaata atggcctgaa 3181 tccagtttac aatgaggatc cctttgtgtt ccgcaaagtg gtccttccgg acttggctgt 3241 gctaagattt ggcgtttatg aagaaagcgg aaagattctg ggtcaacgta ttctgccgct 3301 ggacggtttg caggctggct atcggcatgt ttccctgcgc acggaggcta acttccccat 3361 gtcgttgccc atgttgttcg tgaatatcga gctaaagatc tacgtacctg acggctttga 3421 ggacttcatg gccatgttgt cggatccgcg aggtttcgcc ggtgccgcta agcagcaaaa 3481 cgaacagatg aaggcacttg gcattgagga gcagagcggc ggtgccgccc gagatgctgg 3541 caaggccaaa gaggaggaaa agaaggagcc accactagtc tttgagcctg tcacgttgga 3601 atctctgcgc caggagaaag gcttccaaaa ggtgggcaaa aagcaaatca aggagctcga 3661 caccctgcgc aagaagcatg ccaaagagcg cacctcggtg caaaagaccc agaatgcggc 3721 catcgacaag ttgatcaagg gcaagagcaa agacgacatt cgtaacgatg ccaacatcaa 3781 gaattcgatc aatgaccaga ccaagcagtg gaccgacatg atcgccaggc accgcaagga 3841 ggaatgggac atgctgcgcc aacatgtcca ggactcgcag gacgccatga aggcactgat 3901 gctcaccgtt caggcggcgc agatcaagca gctggaggat cgtcatgcca gggacatcaa 3961 ggatctgaat gccaagcaag caaagatgtc ggcggatacc gccaaggagg tacaaaacga 4021 caagaccttg aagaccaaga acgagaagga tcgtcggctg cgtgagaagc gccagaacaa 4081 tgtgaagcgc ttcatggagg aaaagaagca aatcggagtt aagcagggtc gtgcgatgga 4141 gaaactaaag ttggcgcatt cgaagcagat cgaggaattc agtaccgacg tgcaaaagct 4201 tatggacatg tacaaaatcg aggaggaggc gtataagacg caaggaaaaa cggaatttta 4261 tgcctaagat tcccagatca atggtcaaaa ggggaaagag caccgcgata ccaaacagaa 4321 taataaataa aaaaaacaca ctaaaaaaca aaaaaaaaga atgctgattt agctgaagat 4381 gctaacatat atacttttcc ttatatacta catttacaca ctcatcactc gaaaacacac 4441 actcgcccac atcttgaaaa cttaacttta cttacaaata tttatgtata tgtcttatgc 4501 cggaagcata agcttatatt cttaatacct agaattcaaa aacactttgt gctttatatt 4561 tatttaagat tctgatgaag ataaaaggat aaggaaaaaa agagtcaatg agagggccac 4621 gcagtaatgt gtgcagttta ttggggacgt gctcctctcg aattcattgt aatttatttt 4681 gaaaaacaag agaaaaaaaa aacaaccaat gaaaaataaa ggataccaaa atcttgtaag 4741 gtattttgtg ctaacaacac aataaaaacg gtacaccgat aagtttagac cacacacagt 4801 gcgtttcgca gctaaaagaa ctatattttt gttcttttga gcggtgaaca gttcgcactg 4861 tacacaatca tatatgtata cataacacca acctaacacc ctgccccata tagtcgtacg 4921 tttcaagtga acaacttaca tgagtttccg attctccacc taatagctta gccaattaac 4981 taaccagtaa gccgaagcca tcaattaacc agttaagcaa tccaaggcgc ccacaattat 5041 tcggacaccc aaacagcccc agacagaaat gtttatgtaa ttcggtaaaa aaatatagta 5101 agagctggag agtcttttga agagcattta ttttgcaaaa ccttcggagg aaaaccgtta 5161 aaaaaaataa caaaagccga aaacagtttc acatgtcgta tataatataa atataattac 5221 caaagtatta aatgtgtaat tcaaacaaag aaacacccct accggcagtt atatatataa 5281 cacacgctca cacctaccac acacgaaagt aataataatt tctgaattat taaaaacgtt 5341 aaatagttta cttacataaa atgtacattt ttattcgctc tgtattagtt ccgatcttat 5401 ttccaaattg ataacccgaa cgagataaag atattgcgat tgtgtactac cagaaaaaaa 5461 gtagccaaaa atatatacat atatacacac agaacaaagc atacatatgt agatttagta 5521 aatattatac caaagtaaga gacaaaacta acaacttaag atagattctg tttgaattgt 5581 caaaagcgtt tatgttgcac tcaaaatttg ctgtttgcat gtatttgtag ttgttgcaaa 5641 gccaaacgaa aaaaattaac aaagaagaaa accaagtaca taagaaaccg aaaatgtaga 5701 aaattaaatg aacgaaacta aggcaaggat gcaaagaaat gtaatgtaat ttcccataaa 5761 ttctgaattg gttttaaact tgaatatgtg ccctaaagat cgaaaacgga gaagcgttta 5821 cactgtgcta ttaacgaatc gaaaacattt agttaactca tacaaggtaa ctgtactaaa 5881 ttatgtacaa tatttaacca acgcctacga ctatgtattt agagaattga tcgagtttta 5941 tgaatgtgat aagcggttac attttattac acgaacgcga gaaaaagcga atcccaacta 6001 ccctttatct ccaatacttt cgcctttgcc aacactgtct taattataat ttctccccaa 6061 gggcacgagt tgaaggttgg ttggatggag gaaaacgatt gcaaagcttt gtatgatatg 6121 taatataatg tgccaatccc aatgttaacc aaaaaacgag aaagtgaaac gaacattgtc 6181 taactgagat cgcaactaat ttatttattc gctcgtataa tgtatacatt agatagaggc 6241 ctagcctctt agtcgaaaag ccctcaaatt tggcacactt ataacacaca aaaattattg 6301 gcgcgggtaa aaactattcc ggttaatact tcaaggactt gttccttttt ttttcaagtt 6361 attgtttcaa taattgaagg tattacattt actacgaata taattcatac attggcttct 6421 caagagcact attagtgaag gttttttttt tcaaaggcaa gtggactttt ccctaaaacc 6481 aaagaaagcg tataacgaaa acaaacaaga atgttgccat ataaaaccaa aactgaatca 6541 ctcgaggtca atttaagaaa cgttaccccg ccaatcgacg gattctctac acttagtaaa 6601 tgtgtcaatt ttttatgttt attttttata tattttgttg gtattttttt tttttttttg 6661 taatcttaat aagttgtagt ctttaatgaa gcgctagagc aaaaatgtta caggatatgc 6721 acgatggtgt aacccataca cttggggcca ccctgttgta gtttgtactt ctgtgagagc 6781 aaaaacccag attatgatta tgaatagcga tagcaagcga gacagataac tcgcggatgt 6841 atctactatc tacgtattaa ttgattatgt ttttgcgaac aaacaaacaa tgtaaaatga 6901 atagtttaaa aagaggtcgc gggacaagaa ggttcttgtc gatgaaatta acttatatta 6961 aaaatgctgc gtatgaactt atgattatat actatgaact atatatatta aactattatg 7021 attattatta ttatctttat tatgattatt attacgattg ttccgatatc gaataacttt 7081 aattgcaata aatcctattc caaagcgact ct