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LOCUS NM_132193 4246 bp mRNA linear INV 26-DEC-2023 ACCESSION NM_132193 VERSION NM_132193.2 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 4246) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 4246) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 4246) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 4246) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 4246) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 4246) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 4246) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 4246) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 4246) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 4246) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 4246) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 4246) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 4246) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 4246) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 4246) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 4246) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 4246) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 4246) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 4246) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 4246) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 21 (bases 1 to 4246) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 22 (bases 1 to 4246) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 23 (bases 1 to 4246) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NC_004354). On Jul 15, 2014 this sequence version replaced NM_132193.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..4246 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="X" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..4246 /gene="snz" /locus_tag="Dmel_CG1514" /gene_synonym="CG1514; Dmel\CG1514; DmSNX25; Snz; SNZ" /note="snazarus" /map="7C2-7C3" /db_xref="FLYBASE:FBgn0029976" /db_xref="GeneID:31704" CDS 776..4129 /gene="snz" /locus_tag="Dmel_CG1514" /gene_synonym="CG1514; Dmel\CG1514; DmSNX25; Snz; SNZ" /note="CG1514 gene product from transcript CG1514-RA; CG1514-PA; snz-PA" /codon_start=1 /product="snazarus, isoform A" /protein_id="NP_572421.1" /db_xref="FLYBASE:FBpp0071048" /db_xref="GeneID:31704" /db_xref="FLYBASE:FBgn0029976" /translation="MESEEHAVDAMENRRLPLFPIEPEPSVTATQRLTLLATRLLRAL QLNWRIIVSGITLTLLAVIWYYPTFFLFFAFVVYSLVLVFAAVAGTVYIHYIFTTNEP TPPSRVPSRLLYNATKSNIFDLPKPIKNPSNLPLIFGKTVDLQLQQIIEYVLRDFMLP WLGYVVTKPKLINDVVREDLWNAIQKIHERALRMDAAKIIAVDMVNRVTVHLEKIRIA EARAAETNTPPVFSTNSYLADEEKEMEFLRKLCEIMVILLLPRGYSLPPLKVLLSEIL SYKIFFPMIKMLTAPDYINQKVVQNIETRLAAAAMSKRSYEYAASFEDFLKIINNSGN LEELSLIRKSIVNDLMHATTMQNLQRAKGLDPDHEDHSLSKSELTAAVRLKRYVRQLT MAKGECEKNLAKFGWNGNYSSDIDLTLVEILNTAVGRRYFTLFLEPLKASALIGFYLA VEEIKHAHKSASHQLGTEIFYTYIRVPKSEIQIDKHERKLIETFLLGDAEPDIFYDIQ RNVLRTLEEKYYPPFVLSDQYRQLKEALDSNEIADPTLLMCHTIGDVQEPLADEQPGA ADGLNGGAGGAIDVAAHTSYARRKLEQIQERIDKKNQALDALKYSVKPESKVLTILEK EMEWLKSEKRQTEAHLRRTDAWTEHLGKWKATIQSVEVSDEKESLQFMILVHVDEDIN APVQPTSSKNGDSGHANLRKRPSGISSGWVVMRSLNQVHELQRKLRHVSSNLKAIDLP TNFKFFFLKTDRHGQEKAKSQIQKFLNFILEDDHLNGSEAIYTFLSPSSDHLKQSLPS PKKSKFSLSTLFRSDAGKAHEASKATDPFWGLQRDDEDISTYLDGESGGEAKMLAADL DSKDSIAEPMYALMGEIFDMGGVFKWLRKSLISFVQITYGRTINRQIRESVAYLFEES MLHNYFSAILKSFWPGGVLASAYPTRSEDMREMTTTAAKALLTDHIPEVLCNLVGAQA AKRGVLKVFDALQNPAYNKQLFYELLEILMIEFFPEIRQLRVSNSNGTKLNTATAGAA AASAAAALVAATASASLPSLNHSGGGHSASTGGHQNHQGSSSASGSSAGASGATGGGA ASHHQSHYHHGSHHHQQQQHHHSQAGSSK" misc_feature 1199..1675 /gene="snz" /locus_tag="Dmel_CG1514" /gene_synonym="CG1514; Dmel\CG1514; DmSNX25; Snz; SNZ" /note="PXA domain; Region: PXA; pfam02194" /db_xref="CDD:460484" misc_feature 2039..2368 /gene="snz" /locus_tag="Dmel_CG1514" /gene_synonym="CG1514; Dmel\CG1514; DmSNX25; Snz; SNZ" /note="Regulator of G protein signaling (RGS) domain found in the Sorting Nexin 25 (SNX25) protein; Region: RGS_SNX25; cd08720" /db_xref="CDD:188675" misc_feature 2708..3139 /gene="snz" /locus_tag="Dmel_CG1514" /gene_synonym="CG1514; Dmel\CG1514; DmSNX25; Snz; SNZ" /note="The phosphoinositide binding Phox Homology domain of Sorting Nexin 25; Region: PX_SNX25; cd06878" /db_xref="CDD:132788" misc_feature order(2921..2929,3008..3013,3047..3049) /gene="snz" /locus_tag="Dmel_CG1514" /gene_synonym="CG1514; Dmel\CG1514; DmSNX25; Snz; SNZ" /note="putative phosphoinositide binding site [chemical binding]; other site" /db_xref="CDD:132788" misc_feature 3419..3736 /gene="snz" /locus_tag="Dmel_CG1514" /gene_synonym="CG1514; Dmel\CG1514; DmSNX25; Snz; SNZ" /note="Sorting nexin C terminal; Region: Nexin_C; pfam08628" /db_xref="CDD:462541" ORIGIN 1 aaagagatac aacacttcgc gcagggcgaa gaagcaaagc aaagggcaaa attcataaac 61 ataacagtaa agatagtgta tagccgggcg tgaaatgtaa tgaatcggat tcatgacgtg 121 acgtgttatc agggccagcc caatcccaac tgcgcagcag cagcgacagc aacaacaata 181 acaacaacac atcaagctga atcgaaggag cgtgtaatca gtaatcagag tcgcttgttt 241 tgatttcctt tcctcggaaa cgaatcaaca cgaaacgaga cgagacgatt cgaaacgaaa 301 tgaaatcaaa actccgctcc ggataaagct ggtcaaacca atcaacttgt tgcggatccg 361 cagcgtcgcc cagtattgat ttggcgcata ttgccgacag ttgtggttcc gatttcgatt 421 cccagccagc tgtctctctg cccatatatt tcaatatacg acggacgctt ctccaaaagc 481 cgatacaata ctgtgcgata ccatatttgt attcgtttct cattcgttga cgggcgaggc 541 ggtggaggcg gcggtggagg ttaagaagaa gaaggagagg tcgtcgacaa cggagcagta 601 gaagaaggag gaggtggtgg acaccagacc aaagcggaat tgacgcaatt gttgagaact 661 atttttaatg gtcagcgggt cgaaaatgta caaaactcat caaatattca gaagaagtag 721 gcaataaggt gaggaggcag tgattcggaa gtcccgaatc gaagtcaatc ggccgatgga 781 atcagaggag cacgctgtgg acgccatgga gaatcgccgt ttgccactgt ttcccatcga 841 accggagcca tccgtaacgg caacgcaacg cctaacgctc cttgccaccc gactactacg 901 tgcattgcaa ttaaattgga ggattattgt ttcgggcatc acgcttacat tgctggccgt 961 catctggtat tatcccacct tctttctgtt cttcgccttt gtggtctatt ccctggtctt 1021 ggtttttgcg gctgtggcgg gaaccgtcta tatccattat atattcacca ccaacgagcc 1081 gacgccacca agtcgcgtgc cctcgcgatt gctctacaat gccaccaaaa gcaacatctt 1141 cgatctaccc aagcccatca agaatccatc gaatttgccc ctgattttcg gcaaaacagt 1201 ggacctgcag ctccagcaga tcattgaata tgtgctgcgc gattttatgc tgccctggtt 1261 gggctacgtg gtcaccaagc ccaagctgat caacgatgtg gtgcgcgaag atctgtggaa 1321 cgcgatacag aagatccatg agcgcgccct cagaatggac gccgccaaga tcatagccgt 1381 ggacatggtc aaccgggtga cagtgcatct ggagaagatt cgcatcgctg aggccagagc 1441 agctgaaacc aacacgccgc cagtttttag tacaaactcg tacctcgccg acgaggagaa 1501 ggagatggag ttcctgcgca agctttgcga gattatggtg atcctgctgc tgccacgcgg 1561 ttattccctg cccccattga aggtcttgct cagcgagatt ctctcctaca agattttctt 1621 tccgatgatc aaaatgctga cagcaccgga ctacatcaac cagaaggtgg tccaaaacat 1681 tgaaactcgc ttggcagcgg cggccatgag caagagaagc tacgagtatg cagccagctt 1741 cgaggatttc ctcaaaatca tcaacaactc gggcaacctc gaggagctct cgctcatccg 1801 caagagcata gtaaacgatc tgatgcatgc tactaccatg cagaatctac agcgtgccaa 1861 aggcctcgat ccggatcacg aggaccactc gctctccaag tcggagctca cagccgccgt 1921 ccgactgaag cgctacgtac gccaactcac aatggccaag ggcgagtgcg agaagaatct 1981 ggccaagttc ggctggaatg gcaattactc gagtgatatt gacctaacac tggtcgagat 2041 cctaaacact gcggttggcc ggcgctactt caccctgttc ctggagccgc tgaaggctag 2101 cgctctgatt ggtttctacc tggccgtgga ggagatcaag cacgcgcaca agtcggccag 2161 ccatcagctg ggcacggaga tcttttacac ctacatcaga gtgcccaagt cagagatcca 2221 gattgacaag cacgaacgca aactgatcga gacgttcctg ctgggagatg ccgagcctga 2281 catcttctat gacatccagc gcaatgtact acgcacgctg gaggaaaagt actatccgcc 2341 atttgtgctc agcgatcaat atcgtcagtt gaaggaggca ttggactcca atgagattgc 2401 agatcccacg ctgctaatgt gtcacaccat tggcgatgta caggagccgc tggcggatga 2461 gcaaccgggc gcggcggatg gactaaatgg cggagctggt ggtgccatcg atgtggccgc 2521 ccacacatcc tatgcacgac gaaaattgga acaaatacag gaacggattg ataaaaagaa 2581 tcaggcgctg gacgccctca aatattccgt gaagccggag tccaaggtgc tgaccattct 2641 cgaaaaggag atggagtggc tgaagagcga gaagcgacag acagaggcgc atttgcgtcg 2701 cacggacgcc tggacagagc atctgggcaa gtggaaggct accatccaaa gtgtagaggt 2761 ctccgatgag aaagagtcct tgcagtttat gatcttggtt catgtggacg aggatattaa 2821 tgccccagta caaccgactt catccaaaaa cggtgacagc ggccatgcca atctacgtaa 2881 gcgaccgtcg ggcatttcca gtggttgggt agtaatgcgc tcccttaatc aagtccatga 2941 actacaacgg aagctgagac acgtgagctc taacctgaag gccatcgacc tgcctacgaa 3001 ctttaagttc ttttttctga aaacagatcg tcatggtcag gaaaaggcca agtcacagat 3061 tcagaagttc ttgaatttta tcctggagga cgatcatttg aatggcagcg aggccatcta 3121 cacgtttctt agcccaagtt ccgaccacct gaaacaatcg ctgccctcgc caaagaagtc 3181 caaattctcg ctatctacgc tattccgcag cgatgctggc aaagctcacg aggccagcaa 3241 ggcaaccgat ccgttttggg gtctgcagcg cgatgacgag gatatatcta cctatttaga 3301 cggcgagtcc ggcggtgagg ctaaaatgct agcagcggat ctggatagca aggattcgat 3361 agcagaaccg atgtacgctc taatgggcga aatctttgac atgggcggag ttttcaagtg 3421 gttgcgtaag agtctcatct cgtttgtgca gatcacatac ggccgtacga tcaatcgaca 3481 gatccgcgaa tcggtggcct atctctttga ggagtctatg ctgcacaact acttttcggc 3541 catcctcaag tcattttggc caggcggagt tcttgcctcc gcctatccga cgcgatcgga 3601 ggatatgcgc gaaatgacca ccacggcggc caaggccctg ctcaccgatc acataccgga 3661 ggtactgtgc aacctggtcg gtgcacaggc tgccaaacgg ggtgtcctta aggttttcga 3721 tgccctgcag aatcccgcct acaacaagca gctattctac gagctgctgg agatacttat 3781 gattgagttc tttcctgaaa tccgacaatt gcgcgtcagc aactccaatg gaaccaagtt 3841 aaatacggct actgctggag cggcagctgc atccgccgct gcggcactgg tggctgccac 3901 ggcatcagct tcgctgccct cgcttaatca tagtggtggg ggtcacagtg catccacggg 3961 gggtcaccaa aaccatcagg gatcctcgtc ggccagcgga tcctcagctg gcgcgagtgg 4021 cgccaccggt ggtggtgccg cctcgcacca ccaatcgcat taccaccacg gatcccacca 4081 ccaccagcag cagcagcacc accattcgca agcgggcagt tcgaagtgaa gtgaacttaa 4141 gaagaaccac ttcgttttag attttacttt aacctaaacc ctttttttta tttatgttat 4201 gttttgtttg attttatgtt caatgtttaa tgctctccct ctttct