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LOCUS NM_001298300 4352 bp mRNA linear INV 26-DEC-2023 variant K, mRNA. ACCESSION NM_001298300 VERSION NM_001298300.1 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 4352) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 4352) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 4352) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 4352) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 4352) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 4352) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 4352) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 4352) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 4352) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 4352) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 4352) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 4352) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 4352) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 4352) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 4352) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 4352) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 4352) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 4352) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 4352) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 4352) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 21 (bases 1 to 4352) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 22 (bases 1 to 4352) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 23 (bases 1 to 4352) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NC_004354). ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..4352 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="X" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..4352 /gene="rdgB" /locus_tag="Dmel_CG11111" /gene_synonym="CG11111; Dmel\CG11111; DrdgB; DrdgBalpha; hypoF; ota1; rdbB(ota1); RdgB; RDGB; rdgBalpha; RdgBalpha; RDGBalpha; x36" /note="retinal degeneration B" /map="12C1-12C4" /db_xref="FLYBASE:FBgn0003218" /db_xref="GeneID:32340" CDS 373..4227 /gene="rdgB" /locus_tag="Dmel_CG11111" /gene_synonym="CG11111; Dmel\CG11111; DrdgB; DrdgBalpha; hypoF; ota1; rdbB(ota1); RdgB; RDGB; rdgBalpha; RdgBalpha; RDGBalpha; x36" /note="CG11111 gene product from transcript CG11111-RK; CG11111-PK; rdgB-PK; receptor-degeneration-II; receptor degeneration B" /codon_start=1 /product="retinal degeneration B, isoform K" /protein_id="NP_001285229.1" /db_xref="FLYBASE:FBpp0309250" /db_xref="GeneID:32340" /db_xref="FLYBASE:FBgn0003218" /translation="MLIKEYRIPLPLTVEEYRIAQLYMIAKKSREESHGEGSGVEIII NEPYKDGPGGNGQYTKKIYHVGNHLPGWIKSLLPKSALTVEEEAWNAYPYTRTRYTCP FVEKFSLDIETYYYPDNGYQDNVFQLSGSDLRNRIVDVIDIVKDQLWGGDYVKEEDPK HFVSDKTGRGPLAEDWLEEYWREVKGKKQPTPRNMSLMTAYKICRVEFRYWGMQTKLE KFIHDVALRKMMLRAHRQAWAWQDEWFGLTIEDIRELERQTQLALAKKMGGGEECSDD SVSEPYVSTAATAASTTGSERKKSAPAVPPIVTQQPPSAEASSDEEGEEEEDDDEDEN DAIGTGVDLSANQGGSAQRSRSQSIQMAQKGKFGSKGALHSPVGSAHSFDLQVANWRM ERLEVDSKSNSDEEFFDCLDTNETNSLAKWSSLELLGEGDDSPPPHGGPSSAASVGGR GNSRQEDSIFNQDFLMRVASERGNKRQLRSSASVDRSHDSSPPGSPSTPSCPTTILIL VVHAGSVLDAASELTAKKSDVTTFRGSFEAVMRQHYPSLLTHVTIKMVPCPSICTDAL GILSSLSPYSFDASPSAADIPNIADVPIGAIPLLSVASPEFHETVNKTVAAANIVYHE FLKSEEGHGFSGQIVMLGDSMGSLLAYEALCRSNGSQPGTASGASNSGGDAATNINTH NPLSPRNSRLDDDERFIEADLDAKRLLVAPSPRRRRSSSSSDSRATKLDFEVCDFFMF GSPLSVVLAARKLHDAKAALPRPNCHQVYNLFHPTDPIASRLEPLLSARFSILAPVNV PRYAKYPLGNGQPLHLLEVIQSHPQHFNDGNNLLAGRRLSDASMQSTISGLIENVSLS TIHALQNKWWGTKRLDYALYCPEGLSNFPAHALPHLFHASYWESPDVIAFILRQIGKF EGIPFVGSNDDKDNASFHPGQPREKWIKKRTSVKLKNVAANHRANDVIVQEGREQRLN ARFMYGPLDMITLHGEKVDVHIMKDPPAGEWTFLSTEVTDKNGRISYSIPDQVSLGYG IYPVKMVVRGDHTSVDCYMAVVPPLTECVVFSIDGSFTASMSVTGRDPKVRAGAVDVC RHWQELGYLLIYITGRPDMQQQRVVSWLSQHNFPHGLISFADGLSTDPLGHKTAYLNN LVQNHGISITAAYGSSKDISVYTNVGMRTDQIFIVGKVGKKLQSNATVLSDGYAAHLA GLQAVGGSRPAKGNARMVIPRGCFNLPGQTANPRRRSNAFELQLANISPSSSNINSPS SGNHILLAQLIENAIEKDTPAG" misc_feature 373..1176 /gene="rdgB" /locus_tag="Dmel_CG11111" /gene_synonym="CG11111; Dmel\CG11111; DrdgB; DrdgBalpha; hypoF; ota1; rdbB(ota1); RdgB; RDGB; rdgBalpha; RdgBalpha; RDGBalpha; x36" /note="Lipid-binding SRPBCC domain of mammalian PITPNM1-2 and related proteins (Class IIA PITPs); Region: SRPBCC_PITPNM1-2_like; cd08889" /db_xref="CDD:176898" misc_feature order(433..438,445..447,457..459,466..468,490..492, 547..549,553..555,559..561,565..567,574..576,580..582, 589..591,601..603,613..618,622..624,628..630,634..636, 640..642,655..657,661..663,667..669,676..681,697..699, 703..705,976..978,994..996,1000..1002,1030..1032, 1054..1062,1069..1071) /gene="rdgB" /locus_tag="Dmel_CG11111" /gene_synonym="CG11111; Dmel\CG11111; DrdgB; DrdgBalpha; hypoF; ota1; rdbB(ota1); RdgB; RDGB; rdgBalpha; RdgBalpha; RDGBalpha; x36" /note="putative lipid binding site [chemical binding]; other site" /db_xref="CDD:176898" misc_feature 565..621 /gene="rdgB" /locus_tag="Dmel_CG11111" /gene_synonym="CG11111; Dmel\CG11111; DrdgB; DrdgBalpha; hypoF; ota1; rdbB(ota1); RdgB; RDGB; rdgBalpha; RdgBalpha; RDGBalpha; x36" /note="putative lipid exchange loop [active]" /db_xref="CDD:176898" misc_feature order(724..813,829..903,958..963) /gene="rdgB" /locus_tag="Dmel_CG11111" /gene_synonym="CG11111; Dmel\CG11111; DrdgB; DrdgBalpha; hypoF; ota1; rdbB(ota1); RdgB; RDGB; rdgBalpha; RdgBalpha; RDGBalpha; x36" /note="putatative regulatory loop [active]" /db_xref="CDD:176898" misc_feature 862..864 /gene="rdgB" /locus_tag="Dmel_CG11111" /gene_synonym="CG11111; Dmel\CG11111; DrdgB; DrdgBalpha; hypoF; ota1; rdbB(ota1); RdgB; RDGB; rdgBalpha; RdgBalpha; RDGBalpha; x36" /note="putative PKC phosphorylation site [posttranslational modification]; other site" /db_xref="CDD:176898" misc_feature 2560..3105 /gene="rdgB" /locus_tag="Dmel_CG11111" /gene_synonym="CG11111; Dmel\CG11111; DrdgB; DrdgBalpha; hypoF; ota1; rdbB(ota1); RdgB; RDGB; rdgBalpha; RdgBalpha; RDGBalpha; x36" /note="DDHD domain; Region: DDHD; pfam02862" /db_xref="CDD:460725" misc_feature 3547..3942 /gene="rdgB" /locus_tag="Dmel_CG11111" /gene_synonym="CG11111; Dmel\CG11111; DrdgB; DrdgBalpha; hypoF; ota1; rdbB(ota1); RdgB; RDGB; rdgBalpha; RdgBalpha; RDGBalpha; x36" /note="This domain is found in Saccharomyces cerevisiae protein SMP2, proteins with an N-terminal lipin domain and phosphatidylinositol transfer proteins; Region: LNS2; smart00775" /db_xref="CDD:197870" ORIGIN 1 tcagttcgga atcaaacgcg agccgagtcg caatcgcaac tttgccgccg cgcagcgcac 61 gctgtttttt tttcagtgtg tcatagacga cgtgccgcca ccccacgcca atcacccccc 121 tcgccacaaa aaacaaaaaa aaaacgtcgg acgacagccg cgtcgcgcct tcacatcatc 181 cagccatgac cagcggcggc aatcgatgat tgccattccc tcagccaacg agagccaata 241 gaggcagccg gaaaggagga cgccggaata gtcagtcggt accgtcggaa gagtgcgcca 301 ttcgcagaac gtcaatagcc ggaggggagt ccgccatttc aacgacaagg acccaagtca 361 cgcggtgtca acatgctgat caaggagtac cgcattccgc tgcccctcac cgtcgaggag 421 taccgcatcg cccagctcta catgattgcg aaaaagagtc gcgaggagag ccatggcgag 481 ggcagtggcg ttgagataat catcaatgag ccgtacaagg atggacccgg cggtaatggt 541 caatacacaa agaagatcta tcacgtgggc aatcatctgc ctggctggat taaaagtctc 601 ttgccgaaaa gcgctttaac cgtggaggag gaggcatgga atgcctatcc gtataccagg 661 actcgctaca cctgtccgtt tgtggagaaa ttctcgctgg atattgagac atactattat 721 ccggacaatg gctatcagga caatgtcttc cagctgtccg gaagcgattt gcgtaatcgt 781 atcgtagacg taattgacat tgtcaaggat cagctgtggg gcggtgacta tgtgaaggag 841 gaggatccca agcactttgt gtcggacaag acgggccgtg gacccttggc cgaggattgg 901 ctggaggagt attggcgcga agtgaagggc aaaaagcaac cgacaccgcg caacatgtcc 961 ctgatgaccg cctacaagat ctgccgcgtg gagttccgct actggggcat gcagacaaag 1021 ctggagaagt tcatccacga tgtggcgctg cgcaagatga tgctgcgggc ccatcggcag 1081 gcgtgggcat ggcaggacga gtggttcggc ttgaccatcg aggatatacg cgagctggag 1141 cgacagacgc aactggcgct ggccaagaaa atgggcggcg gcgaggagtg cagcgacgac 1201 agcgtctcgg agccgtacgt cagcacggcg gccaccgccg cctccacaac gggcagcgag 1261 cgaaagaagt ccgctccggc tgtgccgcct attgtcaccc agcagccgcc gagcgccgag 1321 gccagttcgg atgaggaggg cgaggaggag gaggatgacg acgaggacga gaacgatgcc 1381 attggcacgg gcgtggatct gtcagccaac caaggcggat ccgcgcagcg ctcgcgctcc 1441 caaagtattc agatggccca gaagggcaag ttcgggtcaa agggtgccct tcactcgccg 1501 gtgggatctg cccatagctt cgatctccag gtggctaact ggcgtatgga gcgattggaa 1561 gtggactcca aatccaattc ggatgaggaa ttctttgatt gcctggacac caatgagacg 1621 aactcgctgg ccaagtggag ctcgctggag ctgcttggcg agggcgacga cagtccgccg 1681 ccacatggcg gaccctctag tgcagcatcg gtgggtgggc gtggcaactc gcggcaagag 1741 gacagcatat tcaatcagga ctttctgatg cgcgtggcct cggagcgcgg caacaagcgg 1801 cagttacgtt cctcggccag cgtggatcgc agtcacgatt catcgccgcc gggatcgccg 1861 agtacaccgt cgtgtcccac aaccattctg atcctggttg tccatgcggg cagcgttttg 1921 gatgcggcca gcgagctgac cgccaagaaa tccgatgtga ccacattccg tggctccttc 1981 gaggcggtta tgcgacagca ctatcccagc ctcctcaccc atgtgaccat caagatggtg 2041 ccgtgcccct caatatgcac cgacgccctg ggcattctct ccagcctgag tccgtactcc 2101 tttgatgcgt cgccctcggc ggcggatata ccgaatatag ccgatgtccc cattggagct 2161 ataccactac tatctgtggc atcgccagaa ttccacgaga cggtcaacaa gacggttgcc 2221 gctgccaata ttgtctacca tgagtttttg aaatcggagg agggtcacgg attctccggc 2281 cagattgtca tgctgggcga ttcgatgggt tcgctgctgg cgtacgaggc tctctgccga 2341 tcgaatggca gccagccggg cacggcttcg ggtgcctcga attccggcgg agatgcggcc 2401 acaaatataa atacccacaa tccgttgagc ccacgtaatt cgcgattgga cgatgacgag 2461 cgtttcatcg aagccgatct ggatgccaag cgtttgctgg ttgccccatc gccacgtaga 2521 cgccgttcca gctcatccag cgattcgcgt gccaccaaat tggactttga ggtctgtgac 2581 ttcttcatgt tcggatcgcc gctatctgtg gtgctggctg caaggaaact tcacgatgcc 2641 aaggccgccc tgccgcggcc caactgccac caggtctaca atctgttcca tccaaccgat 2701 ccgatcgcct cgcgcctgga gccgcttctg agcgcccggt tttctatatt ggcgccagtc 2761 aatgtcccac ggtacgccaa gtatccgctg ggtaatggac agccattgca tttattggag 2821 gtcattcaat cgcatccgca gcactttaac gatggcaata acctattggc tggtcgccgt 2881 ttgtcggacg catccatgca gagcacgata tcgggtctga ttgagaatgt ctcgcttagt 2941 acgatccatg ccctgcaaaa caaatggtgg ggcacaaagc gcttggatta cgcattatat 3001 tgcccggagg gattgagtaa tttccctgct cacgccttgc cgcacctctt ccatgccagc 3061 tactgggaga gtccggatgt gattgccttt attctacggc agattggcaa attcgagggc 3121 ataccctttg tgggctcaaa cgatgacaag gacaatgcct ccttccatcc cggacagccg 3181 agggagaagt ggattaagaa acggacctcg gttaagctga aaaatgtagc cgccaatcat 3241 cgggccaacg atgtaatcgt gcaggagggc agggagcagc gattgaatgc gagatttatg 3301 tacggacccc tggacatgat cacgctgcac ggtgaaaagg tggatgtgca cattatgaag 3361 gatccgccgg cgggcgagtg gacattcctc agcaccgagg tgacggacaa gaatggacgc 3421 atttcgtaca gcattccgga tcaggtatcc cttggctatg gtatatatcc ggttaagatg 3481 gtggtccgtg gcgatcacac ctcggtggat tgctatatgg cggtggtgcc gccgttaacc 3541 gaatgcgtgg tcttcagcat tgatggctcc ttcaccgctt cgatgtcggt gacgggtagg 3601 gatcccaagg tgcgtgccgg agctgtcgat gtttgccgcc actggcagga gctgggctac 3661 ctgctcatct acatcaccgg acgaccggat atgcagcagc aacgcgtggt gtcctggctg 3721 agccagcaca acttcccgca cggcctgatc tcgttcgccg acggcctgtc caccgatcca 3781 ttgggccaca agacggccta tctcaacaat ttggttcaga accatggaat ctcaattact 3841 gccgcctacg gcagcagcaa ggacattagt gtctacacga atgttggcat gcgaaccgat 3901 caaatcttca tcgtgggcaa ggttggcaag aagctgcagt cgaatgccac cgtgcttagc 3961 gatggctatg ccgcccactt ggccggtttg caggctgtgg gtggttcgcg tccggcgaag 4021 ggcaatgccc gcatggtcat tccacgcgga tgcttcaatc ttcccggcca gaccgcaaat 4081 ccgcggcgca gaagcaatgc tttcgagctg caattggcca acatcagtcc cagcagcagc 4141 aacatcaaca gtcccagcag cggcaaccac atcctactgg cccaactgat tgagaatgcc 4201 attgaaaagg acacgccagc tggctaggaa acttatatgt gtagatggaa atacatattt 4261 tttttgtatg tttttaagtt tatcaccagc gtaaaagtaa cagaagcaat cttcttgtgt 4321 ctcaccaatc ttctcaaaac tagtccttca cg