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LOCUS NM_001298099 5561 bp mRNA linear INV 26-DEC-2023 variant K, mRNA. ACCESSION NM_001298099 VERSION NM_001298099.1 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 5561) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 5561) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 5561) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 5561) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 5561) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 5561) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 5561) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 5561) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 5561) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 5561) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 5561) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 5561) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 5561) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 5561) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 5561) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 5561) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 5561) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 5561) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 5561) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 5561) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 21 (bases 1 to 5561) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 22 (bases 1 to 5561) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 23 (bases 1 to 5561) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NC_004354). ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..5561 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="X" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..5561 /gene="rdgA" /locus_tag="Dmel_CG42667" /old_locus_tag="CG10966" /old_locus_tag="CG12660" /old_locus_tag="Dmel_CG10966" /old_locus_tag="Dmel_CG12660" /old_locus_tag="Dmel_CG15352" /old_locus_tag="Dmel_CG34344" /gene_synonym="CG10966; CG12660; CG15352; CG34344; CG42667; dDGK2; dgk; DGK; dgk-5; DGK2; Dmel\CG42667; RdgA; RDGA; x35" /note="retinal degeneration A" /map="8B7-8C3" /db_xref="FLYBASE:FBgn0261549" /db_xref="GeneID:31826" CDS 1120..5064 /gene="rdgA" /locus_tag="Dmel_CG42667" /old_locus_tag="CG10966" /old_locus_tag="CG12660" /old_locus_tag="Dmel_CG10966" /old_locus_tag="Dmel_CG12660" /old_locus_tag="Dmel_CG15352" /old_locus_tag="Dmel_CG34344" /gene_synonym="CG10966; CG12660; CG15352; CG34344; CG42667; dDGK2; dgk; DGK; dgk-5; DGK2; Dmel\CG42667; RdgA; RDGA; x35" /EC_number="2.7.1.107" /note="CG42667 gene product from transcript CG42667-RK; CG42667-PK; rdgA-PK; receptor-degeneration-I; DAG kinase; DAG-kinase; receptor degeneration A; diacylglycerol kinase; retinal degeneration A" /codon_start=1 /product="retinal degeneration A, isoform K" /protein_id="NP_001285028.1" /db_xref="FLYBASE:FBpp0310580" /db_xref="GeneID:31826" /db_xref="FLYBASE:FBgn0261549" /translation="MQQQQQPSIDQLPEPTASTSNSATTKPTIATATTSTTTTSGNNF HQQLQATTAATMQRLRTTFTRSRTPTGAEMKMQNSLEVPKQVRSASFDEMQLESQRAS SSLLKQQSSSSASADERSSEAGFLQVPLAAHQQRSHSFDSATASAGSDDSGTFLEVPR RLKARRSSSTKTPPPCIHCHYLEEYERRMTAEQRYFIDHRELTALSYSNTSSEASEDE DEVEGHNAEEEEEGSAAIEDAEEETTEAATEEADEDPRTEVESEHDHDPDDDAALEMD IRIGNMSQGSSIEESRARLPRQMRRHTIGSSSVTSASEDEGLEGSDNGSPHFGNTLLP PQPTTPCGITFTLSPTNGDYPSPPHLPLDPGSPPISPCSSNSGRLPALAPIISTPCSS ADADDAGAAMGLPVRARRRSISRQEAIFVEPTGNSLENVSHEEVDNSNTKSSVDTADS LDEASTMATCGSPGAAGGSGASSSHHNAFVVRDIYLMVPDLKRDRAASVDSCFSKLSS NAKTEELQPSADGCFLTVPNINATRSRSVDIVLPTDEQARYKALSMTGSTVTYADGRT ASASNSRRPIRIVPDWTENAVQGEHYWKPTSASGDLCCLNEECIKSGQRMKCSACQLV AHHNCIPFVNEKSTLACKPTYRDVGIRQYREQTTTHHHWVHRKLEKGKCKQCGKFFPM KQAVQSKLFGSKEIVALACAWCHEIYHNKEACFNQAKIGEECRLGNYAPIIVPPSWIV KLPTKGNFKSSIRVSNKNNAASGSGGGGAGGGAGGGGGKSKKQTQRRQKGKEEKKEPR AFIVKPIPSPEVIPVIVFINPKSGGNQGHKLLGKFQHLLNPRQVFDLTQGGPKMGLDM FRKAPNLRVLACGGDGTVGWVLSVLDQIQPPLQPAPAVGVLPLGTGNDLARALGWGGS IFFQGYTDEPIGKILREIGMSQCVLMDRWRVKVTPNDDVTDDHVDRSKPNVPLNVINN YFSFGVDAHIALEFHEAREAHPERFNSRLRNKMYYGQMGGKDLILRQYRNLSQWVTLE CDGQDFTGKLRDAGCHAVLFLNIPSYGGGTHPWNDSFGASKPSIDDGLMEVVGLTTYQ LPMLQAGMHGTCICQCRKARIITKRTIPMQVDGEACRVKPSVIEIELLNKALMLSKRK HGRGDVQVNPLEKMQLHILRVTMQQYEQYHYDKEMLRKLANKLGQIEIESQCDLEHVR NMLNTKFEESISYPKVSQDWCFIDSCTAEHYFRIDRAQEHLHYICDIAIDELYILDHE AATMPQTPDQERSFAAFSQRQAQNERRQMDQAQGRGPGSTALYWSKLPMPYY" misc_feature 2875..3060 /gene="rdgA" /locus_tag="Dmel_CG42667" /old_locus_tag="CG10966" /old_locus_tag="CG12660" /old_locus_tag="Dmel_CG10966" /old_locus_tag="Dmel_CG12660" /old_locus_tag="Dmel_CG15352" /old_locus_tag="Dmel_CG34344" /gene_synonym="CG10966; CG12660; CG15352; CG34344; CG42667; dDGK2; dgk; DGK; dgk-5; DGK2; Dmel\CG42667; RdgA; RDGA; x35" /note="first protein kinase C conserved region 1 (C1 domain) found in type IV diacylglycerol kinases; Region: C1_DGK_typeIV_rpt1; cd20802" /db_xref="CDD:410352" misc_feature 3100..3300 /gene="rdgA" /locus_tag="Dmel_CG42667" /old_locus_tag="CG10966" /old_locus_tag="CG12660" /old_locus_tag="Dmel_CG10966" /old_locus_tag="Dmel_CG12660" /old_locus_tag="Dmel_CG15352" /old_locus_tag="Dmel_CG34344" /gene_synonym="CG10966; CG12660; CG15352; CG34344; CG42667; dDGK2; dgk; DGK; dgk-5; DGK2; Dmel\CG42667; RdgA; RDGA; x35" /note="second protein kinase C conserved region 1 (C1 domain) found in type IV diacylglycerol kinases; Region: C1_DGK_typeIV_rpt2; cd20855" /db_xref="CDD:410405" misc_feature 3559..3945 /gene="rdgA" /locus_tag="Dmel_CG42667" /old_locus_tag="CG10966" /old_locus_tag="CG12660" /old_locus_tag="Dmel_CG10966" /old_locus_tag="Dmel_CG12660" /old_locus_tag="Dmel_CG15352" /old_locus_tag="Dmel_CG34344" /gene_synonym="CG10966; CG12660; CG15352; CG34344; CG42667; dDGK2; dgk; DGK; dgk-5; DGK2; Dmel\CG42667; RdgA; RDGA; x35" /note="Diacylglycerol kinase catalytic domain (presumed); Region: DAGKc; smart00046" /db_xref="CDD:214487" misc_feature 4024..4488 /gene="rdgA" /locus_tag="Dmel_CG42667" /old_locus_tag="CG10966" /old_locus_tag="CG12660" /old_locus_tag="Dmel_CG10966" /old_locus_tag="Dmel_CG12660" /old_locus_tag="Dmel_CG15352" /old_locus_tag="Dmel_CG34344" /gene_synonym="CG10966; CG12660; CG15352; CG34344; CG42667; dDGK2; dgk; DGK; dgk-5; DGK2; Dmel\CG42667; RdgA; RDGA; x35" /note="Diacylglycerol kinase accessory domain (presumed); Region: DAGKa; smart00045" /db_xref="CDD:214486" ORIGIN 1 aacggtcgac gaggcgcgtt gttctagaaa taaataactc atttaaatag cagaacagcc 61 caagcaggcc aaacatttca aagcaaaata ccaaaactct ctggaactac caagttctta 121 aaaaaaaaca ccaacatcgc ccaaaacaca acaaaaacat cgcataccat aagaaaaaca 181 taaacatact gaaaaactta caatatctaa atataaagta actatttttt tgattgtgct 241 tctaagtgtt gtgctaaacc aatattaact tgtacaaata ttcgaaaata ttcaaagata 301 ttccaaagta tttattcaat acttgaaata taagctacga tacaaactta aaacttaaaa 361 ctatgtaaga ctaagatcta gtttttgtgc tttttgaatc ctaactgtta acgtgtaaaa 421 gcacgcaaaa atgtgcacga aattttgact tgattcgaac gactgaaaag tgcgttccat 481 tgtaaagaaa aactaaagcg gcaaaccgaa acgcgcgaaa cttttgatta attaaaagta 541 aaacaaaaaa aaaaaaaacc cagagagccg accaagaact ggcttctggt gtccaacaaa 601 cggccacagg aatcgacaag aaacaacaac aaccacaacg agagtcctga actcagccgc 661 aaaaagaaaa aaaaactttc ctacaggaaa ctaaacaaac cggaaataaa ataaaaaagg 721 aaataggaaa aggaatttaa ctttaacaga aaatcaacat cgaaatggaa ttggccatca 781 gaattgtcaa tccgcagtta gctcgctaca aaaacaacta caacagcaat accagcaaca 841 ttcgcaccag caatagcaaa aaactaatca ccgatagtag ctgcaactgc aacattcagt 901 ccaacgacga caacaacagc agcaacaaca acaacaacaa cccagatatc aacagtgaca 961 acaatataac aacgattaca acagcagcaa gaacaacaag catagacaac aatcaattgt 1021 cagcagcaac aacaacaaca gaggcaaaag gagcatcaat actagcatca aaacaggcag 1081 cagcaacttg caaccacttt gtagcaacaa caacgcgaaa tgcagcagca gcaacaaccg 1141 tccatcgacc agctgcccga gcccacagct tcgaccagca attcggccac aactaaaccg 1201 acaattgcaa cagcaaccac atcgacaaca acaacgtctg gcaacaactt ccaccagcaa 1261 ctgcaagcaa caacggcagc caccatgcaa cgcctgcgaa caacctttac gcgatcacgc 1321 actccaacag gtgccgaaat gaagatgcag aatagcctgg aggtgcccaa gcaggtgcgc 1381 tccgcctctt tcgacgagat gcaactggag tcgcagcgtg cctcctccag tctgctcaag 1441 cagcaatcct catcatcggc ctcggcagac gaacgctcct cggaggctgg cttcctgcag 1501 gttccattgg cggcccatca gcaaagatcc catagcttcg attcggcaac tgcctcggcg 1561 ggcagcgatg actcgggcac ctttttggag gtgccacgac ggctgaaggc tcgacgcagt 1621 tcgtcaacca agacaccgcc gccttgcatc cattgtcact atctggagga gtatgagcgt 1681 cgtatgaccg ccgaacagcg ttacttcatc gatcatcgcg agttaacggc tttgagctac 1741 agcaatacca gctcggaggc gagtgaggat gaggatgaag ttgagggcca taacgcggag 1801 gaagaggagg agggcagtgc ggccatcgag gatgccgagg aggagaccac ggaggcagct 1861 accgaagaag cggatgaaga tccccgcacc gaggttgagt ccgagcatga tcacgatccg 1921 gatgacgatg ccgcattgga gatggatatt cgcattggca acatgagcca aggcagcagc 1981 atcgaggagt cgcgcgcccg cctaccgcga caaatgcggc gtcacaccat cggtagcagc 2041 tcggtcacct cggcctccga ggatgagggc ttggagggct cggacaatgg ttcgccgcat 2101 tttggcaaca ccttgttgcc accacagccg acaacaccat gtggcataac cttcacgcta 2161 agtccaacca atggggatta tccttcgccg ccgcatctgc ccttagatcc cggctcgccg 2221 cccatttcgc cctgctcctc caattcgggt agattgccag ctctggcccc gatcatttcc 2281 acgccctgct cctcggcgga tgccgatgat gctggtgccg ctatgggttt gccagtccga 2341 gcaagacgtc gttcgatttc gcgacaggaa gcgatattcg tggagcccac tggtaactca 2401 ctggagaacg tttcgcacga ggaggtggac aacagcaata ccaagtcatc ggtggacacg 2461 gctgattcac tggacgaggc ctcgaccatg gccacgtgtg gctcacccgg agccgccggt 2521 ggcagtggtg cctcctccag tcatcataac gcctttgttg tgcgagatat ttacctaatg 2581 gtaccggatt tgaagcgaga tcgcgccgcc tccgtggatt cgtgcttctc caagctctcg 2641 tcgaatgcca aaacggagga gctgcaacca agtgccgatg gttgcttcct taccgtaccg 2701 aatataaatg caactcgatc gcgatccgtg gacatcgtgc taccaactga cgagcaagcc 2761 agatataagg ctttatccat gaccggatcc actgtcacct atgcagacgg gcgtaccgct 2821 tcggccagca actcccgtag accgatacgg attgtgcccg attggacgga gaatgccgtg 2881 cagggcgagc actattggaa gcccacctcc gcctccggcg atctctgctg cctgaatgag 2941 gagtgcatta aaagcggcca gcggatgaag tgctccgcct gccaactggt tgcccaccac 3001 aactgcatac cgttcgtcaa cgagaagagc accctggcct gtaagcccac ctatcgggat 3061 gtgggcatac ggcagtaccg tgagcagacc accacccatc atcattgggt gcatcgcaag 3121 ttggagaagg gcaagtgcaa gcagtgcggc aagttctttc ctatgaagca ggcggtgcaa 3181 agcaagctat ttgggtcgaa ggagattgtg gcgttggcct gtgcgtggtg ccacgagatt 3241 taccacaaca aggaggcctg ttttaaccag gccaaaatcg gcgaggaatg tcgtctgggc 3301 aactatgcgc ccatcattgt gccgccatcg tggattgtga agctgccaac caagggcaac 3361 ttcaagtcct cgatacgcgt gagcaataag aacaatgccg catcgggatc aggaggtggt 3421 ggtgctggtg gcggtgccgg tggcggtggt ggcaagagca agaagcaaac gcagcggcga 3481 cagaagggca aggaggagaa gaaggagccg cgagcgttca ttgtgaagcc cattccatcg 3541 ccggaggtaa tcccggtcat tgtgtttatt aatcccaaat cgggcggcaa tcagggccac 3601 aagctgttgg gaaaattcca gcatctgctc aatccgcgcc aggttttcga tcttacgcaa 3661 ggcggtccca aaatgggcct ggacatgttc cgcaaggcgc ccaatctgcg ggtgctggct 3721 tgcggtggcg acggcaccgt cggctgggtc ctttccgtcc tggatcaaat ccaaccgccg 3781 ctccagccag ctccggcggt tggtgtcctg cccctgggca ctggcaacga tctcgctcgc 3841 gctctcggat ggggagggtc tattttcttt cagggctaca cggacgaacc gatcgggaag 3901 atactgcgcg agatcgggat gtcccagtgc gtgctaatgg atcgctggcg ggttaaggtc 3961 acgcccaacg atgacgtcac cgatgaccat gtcgatcgca gcaagcccaa tgtcccattg 4021 aatgtcatca acaactattt ctccttcggc gtggacgcgc acatcgcttt ggaattccat 4081 gaggcacgtg aggctcatcc ggagcgcttc aattcgcgcc tgcgcaacaa gatgtactac 4141 ggccagatgg gcggcaagga tttgattctg cgccaatacc gcaacctctc gcaatgggtg 4201 acgctcgagt gtgatggtca ggactttacc ggaaaattac gcgatgccgg ctgccatgcc 4261 gtgctcttcc taaacattcc cagctatggc ggtggcaccc atccatggaa cgactccttt 4321 ggcgcctcca agccatcgat tgatgacgga ctaatggagg ttgttggcct gaccacctac 4381 cagctgccca tgctgcaggc tggcatgcat ggcacgtgca tttgccagtg ccgcaaggcc 4441 aggatcatca ccaaacgcac cattccgatg caggtggatg gtgaggcatg tcgcgtcaag 4501 ccatcggtga tcgagatcga gctgctcaac aaggcactga tgctgtcgaa aaggaagcac 4561 ggacgcggcg atgttcaagt gaatcccctg gagaagatgc agttgcacat tttgcgcgtg 4621 accatgcaac agtacgagca gtaccactat gacaaggaga tgctacgcaa attggccaat 4681 aagttgggtc aaatcgaaat cgaatctcag tgcgatttgg agcatgtgcg caatatgctc 4741 aacaccaagt tcgaggaatc catctcctat ccaaaggtct cacaggattg gtgcttcatc 4801 gactcctgca ccgctgagca ctacttccgg atcgatcgtg cccaggagca tctgcactat 4861 atctgcgaca ttgccatcga tgaactgtat atcctggacc acgaggcggc caccatgccg 4921 cagacacccg atcaggagcg ctcctttgca gccttctcgc agcggcaggc acagaacgag 4981 cgacgccaaa tggatcaggc ccagggtcgc ggcccgggca gcaccgccct atactggagc 5041 aaacttccga tgccatacta ctagcagccc agagcggcga tctcaatatg ttacgtgcac 5101 tacatgaaca aggatactca ctgcagtcag tgaacaaaaa cggacagacg gcgctgcatt 5161 tcgcctgcaa atacaaccac agggacattg tcaaatatat catcgcaagc gccacacgac 5221 gcctcatcaa catggccgac aaggagcttg gacagacggc gcttcacatt gccgccgagc 5281 agaatcgccg cgacatctgc gtgatgctgg ttgccgccgg cgcccatttg gataccctag 5341 actccggcgg aaatacgccc atgatggtgg ccttcaacaa gaacgccaac gagatagcca 5401 cctatttgga aagtaagcag gggactcagc ccgtcgacgg ctggctcgac gactagacga 5461 atcgacgatc atctcacaaa atgccgcagt tccccgccaa gtagagcaat cgctagacaa 5521 gcttactact tattcaacat tcagacattt aaatgaaaaa c