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LOCUS NM_001298021 2962 bp mRNA linear INV 26-DEC-2023 mRNA. ACCESSION NM_001298021 VERSION NM_001298021.1 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 2962) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 2962) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 2962) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 2962) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 2962) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 2962) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 2962) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 2962) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 2962) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 2962) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 2962) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 2962) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 2962) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 2962) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 2962) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 2962) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 2962) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 2962) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 2962) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 2962) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 21 (bases 1 to 2962) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 22 (bases 1 to 2962) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 23 (bases 1 to 2962) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NC_004354). ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..2962 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="X" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..2962 /gene="Cdc7" /locus_tag="Dmel_CG32742" /gene_synonym="anon-WO03040301.250; cdc7; cdc7-related; CG32742; CG8655; CG8656; CT25076; Dmel\CG32742; l(1)G0148; L(1)G0148; l(1)G0149; l(1)G0461" /note="Cdc7 kinase" /map="6C3-6C3" /db_xref="FLYBASE:FBgn0028360" /db_xref="GeneID:31598" CDS 309..2408 /gene="Cdc7" /locus_tag="Dmel_CG32742" /gene_synonym="anon-WO03040301.250; cdc7; cdc7-related; CG32742; CG8655; CG8656; CT25076; Dmel\CG32742; l(1)G0148; L(1)G0148; l(1)G0149; l(1)G0461" /EC_number="2.7.11.1" /note="CG32742 gene product from transcript CG32742-RB; CG32742-PB; Cdc7-PB; lethal (1) G0148" /codon_start=1 /product="Cdc7 kinase, isoform B" /protein_id="NP_001284950.1" /db_xref="FLYBASE:FBpp0310032" /db_xref="GeneID:31598" /db_xref="FLYBASE:FBgn0028360" /translation="MADRVMCQELATPGSHYRRPKTGVPSTNVVYANGGGSWRAAPRQ TQRLPRQTVQQYATGTPATGSAGRHSGRAFATAGATEEQTVEFNGAAVMGLPATPRTT KQARNKSEAINDLLTRIPDIGKLFDVHSRIGNGTFSTVLLGTLRRESHLPDSLRRKFA IKHHIPTSHPDRIMKELQCMTKMGGKENVVGIHCCMRYDASAAFVMPFMAHDRFQDFY TRMDVPEIRQYMRNLLVALRHVHKFDVIHRDVKPSNFLYNRRRREFLLVDFGLAQHVN PPAARSSGSAAAIAAANNKNNNNNNNNNSKRPRERESKGDVQQIALDAGLGGAVKRMR LHEESNKMPLKPVNDIAPSDAPEQSVDGSNHVQPQLVQQEQQQLQPQQQQQQQQQQQQ SQQQQQPQQQSQQQHPQRQPQLAQMDQTASTPSGSKYNTNRNVSAAAANNAKCVCFAN PSVCLNCLMKKEVHASRAGTPGYRPPEVLLKYPDQTTAVDVWAAGVIFLSIMSTVYPF FKAPNDFIALAEIVTIFGDQAIRKTALALDRMITLSQRSRPLNLRKLCLRFRYRSVFS DAKLLKSYESVDGSCEVCRNCDQYFFNCLCEDSDYLTEPLDAYECFPPSAYDLLDRLL EINPHKRITAEEALKHPFFTAAEEAEQTEQDQLANGTPRKMRRQRYQSHRTVAASQEQ VKQQVALDLQQAAINKL" misc_feature 678..2237 /gene="Cdc7" /locus_tag="Dmel_CG32742" /gene_synonym="anon-WO03040301.250; cdc7; cdc7-related; CG32742; CG8655; CG8656; CT25076; Dmel\CG32742; l(1)G0148; L(1)G0148; l(1)G0149; l(1)G0461" /note="Catalytic domain of the Serine/Threonine Kinase, Cell Division Cycle 7 kinase; Region: STKc_Cdc7; cd14019" /db_xref="CDD:270921" misc_feature order(702..716,726..728,786..788,792..794,822..824, 876..878,924..935,945..947,951..956,1053..1055,1059..1061, 1065..1070,1074..1076,1110..1112,1119..1121,1701..1703, 1707..1718,1722..1724,1839..1841) /gene="Cdc7" /locus_tag="Dmel_CG32742" /gene_synonym="anon-WO03040301.250; cdc7; cdc7-related; CG32742; CG8655; CG8656; CT25076; Dmel\CG32742; l(1)G0148; L(1)G0148; l(1)G0149; l(1)G0461" /note="active site" /db_xref="CDD:270921" misc_feature order(702..713,720..722,726..728,786..788,792..794, 876..878,924..935,939..941,1065..1070,1074..1076, 1110..1112) /gene="Cdc7" /locus_tag="Dmel_CG32742" /gene_synonym="anon-WO03040301.250; cdc7; cdc7-related; CG32742; CG8655; CG8656; CT25076; Dmel\CG32742; l(1)G0148; L(1)G0148; l(1)G0149; l(1)G0461" /note="ATP binding site [chemical binding]; other site" /db_xref="CDD:270921" misc_feature order(822..824,951..953,1053..1055,1059..1061,1119..1121, 1701..1703,1707..1718,1722..1724,1839..1841) /gene="Cdc7" /locus_tag="Dmel_CG32742" /gene_synonym="anon-WO03040301.250; cdc7; cdc7-related; CG32742; CG8655; CG8656; CT25076; Dmel\CG32742; l(1)G0148; L(1)G0148; l(1)G0149; l(1)G0461" /note="polypeptide substrate binding site [polypeptide binding]; other site" /db_xref="CDD:270921" misc_feature order(1107..1127,1308..1316,1683..1724) /gene="Cdc7" /locus_tag="Dmel_CG32742" /gene_synonym="anon-WO03040301.250; cdc7; cdc7-related; CG32742; CG8655; CG8656; CT25076; Dmel\CG32742; l(1)G0148; L(1)G0148; l(1)G0149; l(1)G0461" /note="activation loop (A-loop); other site" /db_xref="CDD:270921" misc_feature <1725..2237 /gene="Cdc7" /locus_tag="Dmel_CG32742" /gene_synonym="anon-WO03040301.250; cdc7; cdc7-related; CG32742; CG8655; CG8656; CT25076; Dmel\CG32742; l(1)G0148; L(1)G0148; l(1)G0149; l(1)G0461" /note="The protein kinase superfamily is mainly composed of the catalytic domains of serine/threonine-specific and tyrosine-specific protein kinases. It also includes RIO kinases, which are atypical serine protein kinases, aminoglycoside phosphotransferases; Region: Protein Kinases, catalytic domain; cl21453" /db_xref="CDD:473864" misc_feature <2151..2330 /gene="Cdc7" /locus_tag="Dmel_CG32742" /gene_synonym="anon-WO03040301.250; cdc7; cdc7-related; CG32742; CG8655; CG8656; CT25076; Dmel\CG32742; l(1)G0148; L(1)G0148; l(1)G0149; l(1)G0461" /note="The protein kinase superfamily is mainly composed of the catalytic domains of serine/threonine-specific and tyrosine-specific protein kinases. It also includes RIO kinases, which are atypical serine protein kinases, aminoglycoside phosphotransferases; Region: Protein Kinases, catalytic domain; cl21453" /db_xref="CDD:473864" ORIGIN 1 tattatcagt agcgccatcg atggtttgat agcacctcag ctcccgcgga acgccgacca 61 gaacacacga ttcagacaat acgaccagtg accagagttg ttcatgtgct ccatccaggg 121 tatccacata caaccaacgg acgctgcgcc acagccagag ttccgggatt aaaagggcgg 181 cgcagcagga ctccggattg gaaacaaaaa ctatccaagc actttttttt tctgtaaaaa 241 ccgccataaa accaccacaa gcaccatcaa tacgccgatg cccaagaaga ttgtgctcct 301 gaggaacaat ggccgatcga gttatgtgcc aggagttggc cacaccaggc agtcactatc 361 gtcgccccaa aacgggagtg cccagcacca atgtggtgta cgccaatggt ggcggatcct 421 ggcgtgcggc gccaaggcaa acccaaaggc tgccgcgcca gaccgttcag caatatgcca 481 ccggcactcc ggcaactgga agcgcgggca ggcattcggg cagagcattc gccactgcgg 541 gcgccaccga ggagcagaca gtggaattca atggagctgc agtcatgggt ctgcccgcca 601 cgccgcgtac aaccaaacag gcacgcaaca aaagcgaagc catcaatgat ctcctcacac 661 gaatcccgga cattggcaag ctgttcgatg ttcacagccg gattggcaac ggaaccttta 721 gcacggtgct gctgggcaca ctgcgccggg aatcgcatct gccggacagt ctgcgtcgca 781 agttcgccat caagcatcac ataccaacca gtcatccgga taggataatg aaggagttgc 841 agtgcatgac caaaatgggg ggaaaggaga acgtggtggg catccactgt tgcatgcgtt 901 atgacgcctc cgccgctttc gtgatgccct tcatggcaca tgaccgattc caggactttt 961 acacgcgcat ggatgtgccc gagatccggc agtatatgcg caatctcctg gtggcactgc 1021 gtcatgtcca caagttcgat gtcatccatc gcgacgtgaa gccgagcaac tttctctaca 1081 atcgacgtcg gcgagagttt ctcctcgtcg atttcggtct ggcccagcat gtgaatcctc 1141 cggctgcgcg atcttccgga agtgccgccg ccatcgccgc agccaacaac aaaaacaaca 1201 acaataataa caataataat agcaaacggc cacgagagcg cgaatcaaag ggggatgtgc 1261 agcaaattgc gctggatgct ggtttgggtg gagcagtgaa gcgtatgcgt ttgcacgagg 1321 agtccaacaa gatgcccctg aaaccggtca acgatattgc gccaagcgat gcgccggagc 1381 agtcagtaga tgggtccaat cacgtccagc cacagctagt gcagcaagag cagcaacaac 1441 tgcagccgca acagcagcag caacaacagc agcagcaaca acagtcgcaa cagcagcagc 1501 agccgcagca gcagtcgcaa cagcagcacc cacaacgaca gccacaactg gcgcagatgg 1561 atcaaacagc atcgacgcca tctggcagca agtacaatac gaatcgaaat gtctcggcag 1621 cagcggctaa taatgccaag tgcgtttgct ttgcaaatcc ctcagtttgc ctcaactgtc 1681 tgatgaagaa ggaggtgcac gcctccaggg caggaacacc tggctatcgg ccgcccgagg 1741 ttctgctcaa gtacccagat cagaccactg ccgtggacgt ttgggcggcg ggtgtgatat 1801 tcctttcgat catgtcaacg gtgtatccgt ttttcaaagc gcccaacgat tttatcgcgc 1861 tggccgagat tgtaacaata tttggagatc aggcgatacg gaagacggcc ttggctctcg 1921 accgtatgat caccctgagc cagaggtcca ggccactgaa tctgcgaaag ttgtgcctgc 1981 gctttcgcta tcgttccgtt tttagtgatg ccaagctcct caagagctac gaatctgtgg 2041 acggaagctg cgaagtgtgc cggaattgtg atcaatactt cttcaactgc ctatgcgagg 2101 atagcgatta cttgacagag ccactggacg catacgaatg ttttccaccc agcgcctatg 2161 acctactgga tcgcctgctc gagattaatc cccataaacg aattaccgcc gaagaggcac 2221 taaagcatcc attctttacg gccgccgagg aggccgagca gacggagcag gatcagttgg 2281 ccaatggaac gccgcgcaag atgcgtcgac aaagatatca aagtcacaga acggtggccg 2341 cctcacagga gcaggtcaag cagcaggttg cccttgatct gcagcaagcg gccattaaca 2401 agctgtgaaa ctagtcccca ccatgcaaac atacatacac cacttgtaca tacatacata 2461 tactataccc agttcgctga tcatgattgt acatatatat agacccacct caagagcata 2521 tctcattatt gcacccagag ccagaagaaa ctcgtccaat gccccactag gccacattta 2581 cttacctcaa gccgcaggca gataaaacca aatgaaacca cgcaacaaac acacacaaca 2641 ctcacaaaca aacatacaaa tgtatattta aagaaatgtt tcaatcatga acaaaatggg 2701 caaggaatac caaaaaagca aacgaggaga gattgattat gaaatattgt ggccgaaagg 2761 ctacaaaatg ttgtatatta aggaacacga aggcgaccca agtgcatggc cctcatcgcc 2821 cagtggcaaa gaattttgca ctatccccat catgtatagt tcgaatagtc ttgtagctaa 2881 cctacttagg tataattatt gtatatctga aaaccatgtg aacgaggata taagagcgac 2941 aaatacatat atttataccg tg