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LOCUS NM_001297958 8050 bp mRNA linear INV 26-DEC-2023 potassium channel (SK), transcript variant S, mRNA. ACCESSION NM_001297958 VERSION NM_001297958.1 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 8050) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 8050) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 8050) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 8050) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 8050) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 8050) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 8050) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 8050) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 8050) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 8050) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 8050) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 8050) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 8050) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 8050) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 8050) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 8050) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 8050) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 8050) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 8050) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 8050) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 21 (bases 1 to 8050) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 22 (bases 1 to 8050) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 23 (bases 1 to 8050) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NC_004354). ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..8050 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="X" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..8050 /gene="SK" /locus_tag="Dmel_CG10706" /gene_synonym="BcDNA:GM01744; CG10706; CG12733; CG4179; Dmel\CG10706; dSK; Sk" /note="small conductance calcium-activated potassium channel" /map="4F5-4F9" /db_xref="FLYBASE:FBgn0029761" /db_xref="GeneID:31456" CDS 604..4128 /gene="SK" /locus_tag="Dmel_CG10706" /gene_synonym="BcDNA:GM01744; CG10706; CG12733; CG4179; Dmel\CG10706; dSK; Sk" /note="CG10706 gene product from transcript CG10706-RS; CG10706-PS; SK-PS" /codon_start=1 /transl_except=(pos:3541..3543,aa:OTHER) /product="small conductance calcium-activated potassium channel, isoform S" /protein_id="NP_001284887.1" /db_xref="FLYBASE:FBpp0310909" /db_xref="GeneID:31456" /db_xref="FLYBASE:FBgn0029761" /translation="MSIQKLNDTTNSGYVSSEETDSLLVSSSNPSKGGGRTALLRQVK SNSTNGPTTGASTSSSGSVSGGGGGSGSGGGSASGSAAGASKPTLMRQDRTSTYLTSP QQSQHARMGSEESMRGGASGAAGHDEDVEQGLVRSSIVPDIEVHEEDQEQHSQQLNAT TMATMTNNQQQQQPTISIMNLSLKPGDSHSHSSSPGSHPNLGTSSYQNLASSIPPSVP SRCRACRNCSRRASTTPTTLIDRSASRDSVKSAFQQGNLSGSMAICISNSALPQQQQL QQQYHLQQQQQQHYQLQQHHLHQQQLQQSQQQVPPVLITSSPTNGSRIIRQSSQPESS STAICCGPHSACVGHAHSHSHTVPNVSLKQLRESSGDGIAGIAADSLRINGGMRPFKQ LRKPASTLSIPGSMKTPSIANREQISSGCNEEAAEALVGIHSDYPRYMEERALTGGNT SRKPSTNSAKHKPNVGYRLGKRKALFEKRKRISDYALVMGMFGIIVMVIENELSSAGV YTKASFYSTALKTLISVSTVILLGLIVAYHALEVQVRLFMIDNCADDWRIAMTWQRIS QIGLELFICAIHPIPGEYYFQWTTKLANKNKTIGTEMVPYDVALSLPMFLRLYLICRV MLLHSKLFTDASSRSIGALNRINFNTRFVLKTLMTICPGTVLLVFMVSLWIIASWTLR QCERFHDEEHANLLNAMWLIAITFLSVGFGDIVPNTYCGRGIAVSTGIMGAGCTALLV AVVSRKLELTRAEKHVHNFMMDTQLTKRLKNAAANVLRETWLIYKHTRLVKRVNPGRV RTHQRKFLLAIYALRKVKMDQRKLMDNANTITDMAKTQNTVYEIISDMSSRQDAIEER LTNLEDKMQSIQEHMESLPDLLSRCLTQHQERIEQRRNFLHPDTAAVAPIQAPTPQSM FNAAPMLFPHSSVPSSNNAAATYHWPTSPILPPISSRTPHLVPDTHMPSNGSAVNSYA SSNKYGSXISERERSNSVINIEMLTIRPDRFWPTSFAPQKPTSTFTSTSMSTSKCKPE FEVAETALRQRVLSPSLSEFQSKSQSRPSSQTQEHILQREIIPMVPIIPIIPVIPEDA ESLGNTNTNSNSSPDQQNVPMTISTVPPSSSAPAFTATGSGGSVTGTSGGIVKSITMN EPITTGSGKPIASNKFTRKRERVCNNSS" misc_feature 2008..2346 /gene="SK" /locus_tag="Dmel_CG10706" /gene_synonym="BcDNA:GM01744; CG10706; CG12733; CG4179; Dmel\CG10706; dSK; Sk" /note="Calcium-activated SK potassium channel; Region: SK_channel; pfam03530" /db_xref="CDD:460958" misc_feature 2608..2847 /gene="SK" /locus_tag="Dmel_CG10706" /gene_synonym="BcDNA:GM01744; CG10706; CG12733; CG4179; Dmel\CG10706; dSK; Sk" /note="Ion channel; Region: Ion_trans_2; pfam07885" /db_xref="CDD:462301" misc_feature 2887..3111 /gene="SK" /locus_tag="Dmel_CG10706" /gene_synonym="BcDNA:GM01744; CG10706; CG12733; CG4179; Dmel\CG10706; dSK; Sk" /note="Calmodulin binding domain; Region: CaMBD; pfam02888" /db_xref="CDD:460739" ORIGIN 1 tcagtatcgc acaaacaaca ctaacggaaa catcaacgtg aaagcgagac ggacgccctc 61 cgtcccgtta tatgctgtgt ctgtctttaa tatatatata gttaaacaaa ataaaaatat 121 caaataaaaa acaagtgcaa gcaaagagaa aagcgcccaa tgcggccaat ggaaatgcca 181 aagaaaatgc agcagctaca aattcgacaa caaatgcaaa tgcgacagca acagcagaag 241 aagcagcagc agcaacaaca tcaactgcaa tttctcaaca cataagtcca ccgaattttc 301 cgtctttgtc gcgcgcgctc acacatatac aagcacacac atccatacac ggagacacat 361 gcatgtgcat aaatggcaat atggacgaac agcagcagca tttgcgttgt ataccaacac 421 agtgacacgc gcgtgccaaa tattgccgat tttatcacac gaacaacaac aacagcaaca 481 acaacaccag cgggaccagc tattaactaa aggagccatt acaacaacaa taacaagatc 541 cagcaaagca acaacaacaa cgaaagcaac gaacattgct ggaaggcgtc gcaaaatatc 601 aaaatgtcaa ttcagaagct taacgacacc acaaactcgg gctacgtgag ttccgaggag 661 acggactcgc tgctggtgag cagctcgaat ccgtcgaagg gcggcggtcg gacggctctg 721 ctccgccagg tgaagagtaa ctcgacaaat gggccaacga cgggggcgtc cacatcgtcc 781 tcgggatcgg tatcgggcgg cggtggtgga tccggttccg gtggcggatc agcatcgggc 841 tcagcagctg gggcttccaa gccaacgcta atgcgtcagg atcgaacatc cacctacctg 901 acaagtccgc agcagtcgca gcacgcgaga atgggttccg aggagagcat gcgaggtgga 961 gccagcggag ctgccggaca cgacgaggat gtggaacagg gcctggtccg tagcagcata 1021 gtgcctgata tcgaagtaca cgaagaggac caagagcaac acagccagca gttaaatgca 1081 acgacgatgg caacgatgac caataaccaa cagcaacagc aaccgaccat atcaattatg 1141 aatttaagcc tcaagccagg cgatagccat agccatagct ccagtccggg tagtcatccc 1201 aatttgggca cctcatcata tcagaatctg gcatcgagca taccgcccag cgtaccgagt 1261 cgctgcaggg cgtgccgcaa ttgcagtcga cgtgcttcca ccacgcccac cacgctgatc 1321 gatcgctccg cctcccgcga cagtgtgaaa agtgccttcc agcagggcaa tcttagcggc 1381 tccatggcca tttgcatatc gaactcggcc ctgccgcagc agcagcagtt gcagcaacag 1441 tatcacctgc aacagcaaca gcagcagcac tatcagttgc agcaacacca tctgcatcag 1501 cagcaactgc agcagtcgca gcagcaggtg ccgccggtgc taatcacatc atcgccaacg 1561 aatggatcac ggataatacg gcaaagttca cagccggaat cgagcagcac ggccatttgt 1621 tgtggtcccc attccgcttg cgttggccac gcccactcgc actcgcacac ggtaccgaat 1681 gtttcgctga agcagctgcg cgagagttcc ggcgatggaa tcgcgggcat tgcagccgac 1741 tctctgcgga tcaacggtgg catgcggccc ttcaagcagc tccgcaaacc ggcgtcgaca 1801 ctctcaattc ctggctcgat gaaaacacct tccattgcga accgggaaca gatctcatct 1861 ggatgcaacg aagaagcggc cgaggcacta gtgggtatcc actcagacta ccctaggtat 1921 atggaagaac gtgctcttac tggcggcaat acgtccagga agccatcaac aaactcggcc 1981 aaacacaaac ccaatgtggg ctatcgcctg ggaaagagga aagccctctt cgagaagcgc 2041 aaacggatca gcgattacgc cctggtcatg ggcatgttcg ggatcatcgt gatggttatc 2101 gaaaacgaac tgagcagtgc cggtgtctac acaaaggcat cgttctactc gacagcgtta 2161 aaaaccttaa tatctgtttc gactgtgatt cttttaggac ttatagtagc ttaccatgct 2221 ttggaagtgc aggtgagatt attcatgata gataactgcg ctgacgattg gaggatcgca 2281 atgacatggc aacgaattag tcaaataggg ttagaacttt ttatatgcgc tatacatcca 2341 attcctggcg aatactattt ccagtggacg acgaaattgg ccaataagaa taaaacaatt 2401 ggcaccgaaa tggtgccata tgacgtagct ttatcattac ctatgttcct tcgattatat 2461 ttaatctgcc gcgtaatgct gctgcattca aagctattca cagatgcatc atcacggagc 2521 attggcgctc tcaataggat taattttaac acaagattcg ttttaaaaac tctaatgaca 2581 atatgtccgg gaacggttct attggtcttc atggtctcgc tgtggatcat cgcatcgtgg 2641 acgctgcgtc agtgcgaaag atttcatgat gaagaacacg cgaatctttt gaatgcaatg 2701 tggctgatag cgataacatt tttgagtgtt ggtttcggtg atattgttcc gaatacgtac 2761 tgtggacgtg gtatcgctgt cagtacagga ataatgggcg ccggctgtac ggctctactg 2821 gtggccgtag tctctcggaa actggagctg acccgtgctg agaagcatgt gcacaacttc 2881 atgatggaca cgcagttgac gaaacggctg aaaaatgctg cggcgaatgt tctgcgtgaa 2941 acttggctca tttacaaaca tacaagacta gtaaaacggg ttaatcccgg ccgtgtaaga 3001 acccaccaaa gaaagttcct tctagctata tatgcgttgc gaaaagttaa aatggatcag 3061 cgcaaactaa tggataatgc aaacacaata actgacatgg ctaagacaca aaacacggtc 3121 tacgagataa tatcggacat gtctagccgt caggatgcca tcgaagagcg tttaaccaac 3181 ctagaggaca aaatgcagag catacaagag cacatggaaa gccttccaga cctattgtct 3241 cgatgtctga cccagcacca ggagcggatc gagcagcggc ggaacttttt acatcctgac 3301 acagctgcag ttgcccccat tcaagcgcca acgccccaat cgatgttcaa tgcagcgccc 3361 atgctgtttc cacattctag tgttccctca tccaataacg ccgctgctac ttaccattgg 3421 ccaacaagcc ctattttgcc acctatatct agtagaacac cacatttagt gcctgatact 3481 cacatgccat caaatggatc tgcagttaat agctacgcat cttccaacaa atacggcagc 3541 tgaatatcag aaagagagcg ctccaactcc gtgattaaca tcgagatgct aacaataagg 3601 ccggatcgat tctggccaac ctcattcgca ccccaaaaac caacatcaac atttacatca 3661 acatcaatgt ctacgtcaaa gtgtaaaccc gaattcgaag tggccgagac agcgctgagg 3721 caacgcgtgc tatcgccgtc gttatcggag tttcaatcga aatcgcaatc gagaccatcg 3781 tcacaaacgc aagagcacat tttgcaaagg gagatcatac cgatggtacc gatcataccg 3841 atcataccag tgataccgga ggacgccgaa tcgttgggaa acaccaatac gaacagcaac 3901 agttcgcccg atcagcagaa tgtgcccatg actataagta cagtaccgcc atcgagttca 3961 gcgcccgcat tcacagcgac cggaagcgga ggttcggtga ccggaactag cggtggcatt 4021 gtgaaatcga taacgatgaa cgaaccgatt acgacgggga gcggcaagcc gattgcctcg 4081 aataagttta ctaggaaaag agaacgtgta tgcaataata gtagttaata gtagtagtca 4141 tagttatagt aataatagag gtaaaagtaa tattagtaat tctacaagtc gaatttcgaa 4201 ctcggccttt tgtaaataag cctcttcgag atgagaaaaa agtcaaatgt tagcatatac 4261 atattaatat acagaataca cacactatgt atcctatatc tgtatacgga tatatatagg 4321 cctccccaca aaacatccaa aaagaaagca aaaaaacaat aagcgaaaac cgaacagaat 4381 atatgtatac atatatatgt cattgtgtaa cttttttttt ttgtctaagt tttaggctaa 4441 acgtatttgt aatatttcac cttgggccaa ggcagcctgt acatgcatac taaaatactt 4501 aacataatat agcatgtagg ggggagtgta tgtgtgtgta tgtgcatggg agtgtgcgaa 4561 tgcgagtgta caggaccaga ttggtaagga agttaggtca tatgtaggac atagatcgta 4621 gggcaccagc atgtagaatc cacgtatata aacgctcaga aatagcaaca gaaatagcaa 4681 tagcaaacct taaagatctg gcaccaaaag tccataacag taaattcgta tatcccttaa 4741 agaactgcaa cccccagcac ttccgcttcc ggtgcagcgc caaccaactg caaaacatcc 4801 acgaacatgg caaattctcg tgtccgtctg tctcgaattt gtgtgcatat ataaattgta 4861 tccgaaggat gtgtgtctga cctgactgtg tgtgcgaggc aagtgaaagc ataagcatac 4921 gaggaaccca ttaaagcccc caacaattat acacaaaacg acgcataaca acaaaaaaaa 4981 aaaaagaact acaagaacta aatcccaaaa gaagaacaat gaaaaactat actaactgta 5041 aagtgcatgt tgcgagattt agaaaacagc aaaaccagaa aaccaaaaac taagagataa 5101 tgaaacaaat gaaaccccaa taaccgagaa taaacgaaaa ataaacacac aagatgtaag 5161 ttcttactta atatctacat accatactat gtagatctgg ctttaactaa actaacgaaa 5221 ccaatttaaa ggaaacaagt ttgttgttgt cttctttttc tacacatata ttaaaatata 5281 tatagtatat atacatacat atatatattt tcgttgttgc tgtttttcgc ccattctttt 5341 ctaccaagaa ttatgaactc aattaagaac ctgaatagct tttgaatgaa gttaaagacg 5401 aagattacag tagcgtagac taaactgagt aaacaaatga gaagaaaaga agtcgcaaaa 5461 cgaactattt agtatagtct acatactaaa gtgaacaatt ttaattggaa ttttttgtaa 5521 catattaaag taaatcccat taatatacaa gctagctggc aaatgtgtaa caacaacgga 5581 acaaacaaca agctccagat agaaaataat attaccgaac cgaagtgtac ggaagcgagt 5641 tgatagagca gtgtatagtg tagacataat agcagaagtg gccgagctac gtaaagattt 5701 tctaaagatt ctaaaaggaa cattatatat actatatata tatatataca tatacttact 5761 ataaagtatt aactgagagc atcgaagtta tttaaagtaa aaatcaaagc aagaaaacaa 5821 acaattaggt aatgtgcaac cttctaacgc tttgttaggt tcccaagttt ccaaattgaa 5881 gacaaatgag atatacaact gaattccccg aatagtgccc cccaccatcc agctccccaa 5941 aattccaccc atcatcgcac aaactcccca tttcccccgt cagtgagaca gactctgcat 6001 attatactga accagggcca gaaaggatca aaatatctgt aaactgtaga ttatatagcc 6061 ataggatgca gtccacttta agccaactaa gagtatcgga gttttaacac aatgatttac 6121 cacatctcca agcccctggc ctaagttttg atttatgaaa acgaaactac ccgctaccaa 6181 aaaaagtttc ccaactgtct gataggtctt aacttatatg tatttgtaca actaaaggcc 6241 cagacaagaa atgaaatgaa aaaggagaac aaggaacaag taacaaacca actaaatgaa 6301 cccttaaaca aatgtgtgta tacctattta taatattgaa tatttaaatt gaaatgaacg 6361 ttcaagactg ctgtcaaaat agctttatca caataattaa caaagatcta cacaagacga 6421 taacacacca gacacaacag aacagaacaa aacagaacag aaccgatcag aacaatacta 6481 aggatatcat aatcgattat cgaatcgaaa cagtttatcg aaccggaaac acacagcaac 6541 acacagattc agatacgcgg tatggaatgc ggccagcttt aacgttatgt attcatgcat 6601 atttgggttt caattctaca acaacttaaa acgaatacgc agaataacac cgttattgat 6661 cgatatacaa ttaacgatat atggagtcga atcaaatcga atcgaatcga atcgaattga 6721 atcgaattga attgaattga gtaattggtg caagatcaaa ttcccgtttg aactggtttc 6781 ctaagcccaa ccaaatacct tttaacacga gataaaaacc aaaaactttg atatgaggga 6841 ccgaatttcc aaagacaggt ctttattata caaaataccg aagcagaagc aaaccaacta 6901 acaatgaatt cctaagtaac aacatttaac agtaacaatt tataatacgc aagattttaa 6961 gccgccttag agctgggttc caaaaaaaaa aaaaacaaaa aaaaaactaa ggcacacatt 7021 gaaggatcgt attgcaccat gtccttggtt gactttcgta gcattttagg ttcgagttcc 7081 atgtccagct ttgtgttaca ttgtccattt gtgttttttt ttttaaacta gactcacatc 7141 gaatcgaatt gaatcgataa atgttgtata ctttcttttc ctcagcgaat cgtagagctc 7201 aaggggtact tcgagaatca tgcttcaaca accgtaactc ttctagccaa accaggtcca 7261 atagaacata catatgtatg tacatacgtg tgtatgtata gcccagtcaa tgccaatgct 7321 aatgaagaac tggattcgtg ttttcgaaaa cgtttcgaac cggattgtga cgaagcagcc 7381 attttggtgt atttacacga tagaatctag aaatgggtcc ttctcccaaa aatatccccc 7441 acaccccaaa tccctcctct cgtgcgccca actagatcgg ggtatgcaaa atatatatgg 7501 ttacatatac aatatctaga tatacaacac acatacatat actcgtatat acatgtacag 7561 acggtcaatg aggtgtatac ccaacagccc aaaagccaga aacaaaaaaa aaaacccaaa 7621 agaaaataat aaaaaaaaaa acaaaacaaa aaaaaacaca ctaataagat catatttgac 7681 tttatatgta ttatagtaat gtattcagta gctaaatcga aagccgaagc aaagaccaat 7741 ttattaacaa caaactaata aggaaaaccc aactggaaaa caattattat gttaaactaa 7801 acaataaaaa cataagagga aggcgaaaca attttttatg gagaaaaaaa gatgtgaaaa 7861 caaaagagaa gtaatgaaag taaactagaa tgcgttgcat gaattaaacg aagtggagaa 7921 aaactaatag aaagcaaaac ttgaataaag ctaaacaaat gtcaactaaa accaaacttt 7981 aactaaacct acactaatgc taaaactaaa actaaaataa cattaaatta aaccaactaa 8041 aagaaggacg