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LOCUS NM_001272577 3024 bp mRNA linear INV 26-DEC-2023 mRNA. ACCESSION NM_001272577 VERSION NM_001272577.2 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 3024) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 3024) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 3024) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 3024) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 3024) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 3024) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 3024) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 3024) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 3024) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 3024) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 3024) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 3024) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 3024) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 3024) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 3024) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 3024) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 3024) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 3024) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 3024) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 3024) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 21 (bases 1 to 3024) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 22 (bases 1 to 3024) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 23 (bases 1 to 3024) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NC_004354). On Jul 15, 2014 this sequence version replaced NM_001272577.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..3024 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="X" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..3024 /gene="comt" /locus_tag="Dmel_CG1618" /gene_synonym="CG 1618; CG1618; com; Comt; Dmel\CG1618; DmNSF; dNSF; dNSF-1; dnsf1; dNsf1; dNSF1; Nsf; NSF; NSF 1; NSF-1; Nsf1; NSF1" /note="comatose" /map="11E8-11E8" /db_xref="FLYBASE:FBgn0000346" /db_xref="GeneID:47091" CDS 226..2463 /gene="comt" /locus_tag="Dmel_CG1618" /gene_synonym="CG 1618; CG1618; com; Comt; Dmel\CG1618; DmNSF; dNSF; dNSF-1; dnsf1; dNsf1; dNSF1; Nsf; NSF; NSF 1; NSF-1; Nsf1; NSF1" /note="CG1618 gene product from transcript CG1618-RB; CG1618-PB; comt-PB; N-Ethylmaleimide-sensitive factor; NEM-sensitive fusion protein; N-ethyl-maleimide sensitive fusion protein; comatose; N-ethylmaleimide-sensitive factor 1; N-ethylmaleimide-sensitive fusion protein" /codon_start=1 /product="comatose, isoform B" /protein_id="NP_001259506.1" /db_xref="FLYBASE:FBpp0305521" /db_xref="GeneID:47091" /db_xref="FLYBASE:FBgn0000346" /translation="MAYILKATKCPTDELSLTNRAIVNVGDFPEEIKYADISPAPGQH FIFALEKTVEVPSGYVGFSLVQRKWAMVSINQELEVRPYRFDASSDVITCVSFETDFL QKKTVSQEPYDSDQMAKEFIMQFAGMALTVGQSLVFNFKDKKLLGLAVKSLEAIDPKS LGEGKDTAMRNVRFGRILGNTVVQFEKAENSSLNLQGKSKGKVVRQSIINPDWDFGKM GIGGLDKEFNSIFRRAFASRVFPPELVEQLGCKHVKGILLYGPPGTGKTLMARQIGTM LNAREPKIVNGPQILDKYVGESEANVRRLFAEAEEEEKRLGPNSGLHIIIFDEIDAIC KQRGSVAGNSGVHDTVVNQLLTKIDGVDQLNNILVIGMTNRRDMIDEALLRPGRLEVQ MEISLPNEQGRVQILNIHTKRMREFNKINDDVDNKEIAALTKNFSGAELEGLVRAAQS SAMNRLIKADAKVTVDPEAMEKLKVNRDDFLHSLEHDIKPAFGTAQEILDNMLARGVI NWGAPVSNLLEDGMLYVQQAKAPESSGLVSVLVAGAPNSGKTALAAQLAKMSDFPFVK VCSPEDMVGYTESAKCLHIRKIFDDAYRSMLSCIVVDNVERLLDYGSIGPRYSNMTLQ ALLVLLKKQPPKGRKLLILCTSSRREVLEEMEMLTAFTSVLHVPNLSKPDHVLAVLEN TDIFSKGEIQAIGKKMAGKRVFIGIKKLLGLIDMARQTEQSQRAIKFLSKMEEEGGLD MVARQ" misc_feature 238..474 /gene="comt" /locus_tag="Dmel_CG1618" /gene_synonym="CG 1618; CG1618; com; Comt; Dmel\CG1618; DmNSF; dNSF; dNSF-1; dnsf1; dNsf1; dNSF1; Nsf; NSF; NSF 1; NSF-1; Nsf1; NSF1" /note="Cell division protein 48 (CDC48) N-terminal domain; Region: CDC48_N; smart01073" /db_xref="CDD:215012" misc_feature 556..>699 /gene="comt" /locus_tag="Dmel_CG1618" /gene_synonym="CG 1618; CG1618; com; Comt; Dmel\CG1618; DmNSF; dNSF; dNSF-1; dnsf1; dNsf1; dNSF1; Nsf; NSF; NSF 1; NSF-1; Nsf1; NSF1" /note="Cell division protein 48 (CDC48) domain 2; Region: CDC48_2; smart01072" /db_xref="CDD:215011" misc_feature 880..1410 /gene="comt" /locus_tag="Dmel_CG1618" /gene_synonym="CG 1618; CG1618; com; Comt; Dmel\CG1618; DmNSF; dNSF; dNSF-1; dnsf1; dNsf1; dNSF1; Nsf; NSF; NSF 1; NSF-1; Nsf1; NSF1" /note="first of two ATPase domains of NSF and SEC18, and similar ATPase domains; Region: RecA-like_NSF-SEC18_r1-like; cd19504" /db_xref="CDD:410912" misc_feature <883..>2043 /gene="comt" /locus_tag="Dmel_CG1618" /gene_synonym="CG 1618; CG1618; com; Comt; Dmel\CG1618; DmNSF; dNSF; dNSF-1; dnsf1; dNsf1; dNSF1; Nsf; NSF; NSF 1; NSF-1; Nsf1; NSF1" /note="AAA family ATPase, CDC48 subfamily; Region: CDC48; TIGR01243" /db_xref="CDD:273521" misc_feature order(886..888,1015..1029,1207..1209) /gene="comt" /locus_tag="Dmel_CG1618" /gene_synonym="CG 1618; CG1618; com; Comt; Dmel\CG1618; DmNSF; dNSF; dNSF-1; dnsf1; dNsf1; dNSF1; Nsf; NSF; NSF 1; NSF-1; Nsf1; NSF1" /note="ATP binding site [chemical binding]; other site" /db_xref="CDD:410912" misc_feature order(922..924,931..933,943..945,961..975,1108..1113, 1120..1122,1132..1134,1279..1284,1291..1293,1303..1308, 1381..1383) /gene="comt" /locus_tag="Dmel_CG1618" /gene_synonym="CG 1618; CG1618; com; Comt; Dmel\CG1618; DmNSF; dNSF; dNSF-1; dnsf1; dNsf1; dNSF1; Nsf; NSF; NSF 1; NSF-1; Nsf1; NSF1" /note="hexamer interface [polypeptide binding]; other site" /db_xref="CDD:410912" misc_feature <1801..2331 /gene="comt" /locus_tag="Dmel_CG1618" /gene_synonym="CG 1618; CG1618; com; Comt; Dmel\CG1618; DmNSF; dNSF; dNSF-1; dnsf1; dNsf1; dNSF1; Nsf; NSF; NSF 1; NSF-1; Nsf1; NSF1" /note="AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]; Region: SpoVK; COG0464" /db_xref="CDD:440232" ORIGIN 1 acatcttcct tgaaagttca gaaaggatat agttcacaat tcgttcaaaa attaatatat 61 atatatatag ttatgctgtt tcagtgatac tgtaaacaaa tatcaaacgt taattcgcac 121 acaaagctgc gttttctgac cattaaagta cttccattgg attataatta ttgatttttg 181 tcaaattcta aacaaccccg tgaaaatcag caagaatcta aagaaatggc ttatattttg 241 aaggccacca aatgtcccac ggacgagctt tcgctgacca atcgggctat agtgaatgtt 301 ggtgattttc cggaggaaat caaatatgcg gacatatcgc cggctccggg tcagcacttc 361 atctttgcgc tggagaaaac ggtggaggtg cccagcggct atgttggctt ctccctggtc 421 caacgaaagt gggccatggt gtccattaat caggaactgg aggttcgtcc ctatcgcttt 481 gatgccagct cggatgtcat cacttgtgtg tcctttgaga cggactttct gcagaagaag 541 actgtctccc aggaacccta tgactccgat caaatggcca aggagttcat catgcaattc 601 gccggaatgg cactcaccgt tggccaatca ctggtcttca atttcaagga caagaaactt 661 ctcggcctgg ccgtcaaatc cctagaggcc atcgatccca agagcttggg cgagggcaag 721 gacaccgcga tgcgtaatgt ccgcttcggc cgcatccttg gcaacaccgt ggtgcagttc 781 gagaaggccg agaacagttc gctgaatctg cagggcaaga gcaagggcaa ggtggtccgc 841 cagtccatta taaacccgga ttgggacttt ggcaaaatgg gcatcggtgg cctggacaag 901 gaattcaatt cgatatttcg acgagccttc gcatcccgtg tcttcccacc ggaactggtc 961 gagcagctgg gctgcaagca tgtcaagggc attctacttt atggtccacc gggtacgggc 1021 aaaactctga tggctcgcca aatcggaact atgttaaacg cccgggagcc gaaaatcgtc 1081 aacggtccac agatcctgga caagtacgtg ggcgaatcgg aggccaatgt ccggcgtctg 1141 tttgccgagg cggaggagga ggagaaacgc ctgggtccca acagtggact acatatcatc 1201 atcttcgacg agatcgatgc catttgcaag cagcgtggct ccgtggccgg aaatagtggt 1261 gtccacgaca ccgtcgtcaa tcagttgcta accaaaatcg atggcgttga tcagctgaac 1321 aacattctcg ttatcggcat gaccaatcgc agggacatga tcgatgaggc tttgctgcga 1381 ccgggtcgcc tcgaggtcca aatggagatc agcctgccca acgagcaggg tcgcgtccag 1441 attctcaata tccacaccaa gcggatgcgt gaattcaaca agattaacga cgatgtggac 1501 aacaaggaga tcgctgcgct gaccaagaat ttcagcggtg ccgagctgga gggtttggtc 1561 cgtgccgccc agtcgagtgc catgaaccga ctgatcaagg ccgatgccaa ggtgaccgtt 1621 gatcctgagg ccatggaaaa gttaaaggtc aatcgagatg atttcctgca ctcgctggag 1681 catgacatta agccggcatt cggtacggcc caggagattc tcgacaatat gctggcccgc 1741 ggtgttatca actggggagc accggttagc aatctcctcg aggacggcat gctgtatgtg 1801 cagcaggcca aggctccaga atctagcggc ttggtctccg tactcgtggc cggagcaccc 1861 aactctggca agacggcact ggccgctcag cttgccaaga tgtcagactt tccgttcgtg 1921 aaggtctgct cgccagagga catggtcggc tacactgaat cggccaagtg cctgcacatt 1981 cgtaagatct tcgacgacgc gtatcgttcc atgcttagct gcattgtggt ggacaatgtg 2041 gagcgtctgc tggactacgg atcgattggg ccgcgatatt ccaatatgac gctacaggca 2101 ctgctggtgc tgctcaagaa acagccgcca aagggccgca aattgctcat attgtgcaca 2161 tctagcagga gggaggtcct ggaagagatg gagatgctga cggccttcac ctcggtgctc 2221 cacgtgccca atctttccaa gcccgaccac gttctggccg tgctggagaa cacggatatc 2281 tttagcaagg gcgaaatcca ggcgattggc aagaagatgg ccggaaaacg cgtgtttatt 2341 ggcatcaaga agctgctggg tctcattgac atggctaggc aaacggagca atcacagcgg 2401 gccataaagt tcctgtccaa gatggaagag gagggtggtc tcgacatggt ggcgcggcag 2461 taaggcatct taaactgcat gtgcccaaat ggagtctcaa ttattagctt ctaagtgcta 2521 aggacgggcg atgaatagcg atgaaaccaa atcagaatct caatgtacac gcttcgcgat 2581 gtttgttcgg tcccaaagcc cagataaaaa tcacaatcca catcccggag gagtttcgtg 2641 tgcttctgag ttcccccaca gagctcaatc aaatcagaca gatatgtgag acccgtgacc 2701 tgaagatgat ggcatataaa tgacataata tatggcttaa atggacagat actcaattac 2761 atttataaat aattaacacg cgtagccact aactcgttaa aggcatgata atctttctcg 2821 ttacctttta attttaggac ttttgcttca gtaaattctc aataggaaac gaaaaaacgg 2881 gagaaaacac caaagtattt gcctttgggc attgtgaacg ttgtttatcg gtaactaaac 2941 taattaaata tttattaaat caaatattgt taaccgccaa tgttataatt atatcttgaa 3001 taaagtaaaa caaacttaaa ttcc