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LOCUS NM_001272159 7235 bp mRNA linear INV 26-DEC-2023 ACCESSION NM_001272159 VERSION NM_001272159.1 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 7235) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 7235) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 7235) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 7235) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 7235) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 7235) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 7235) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 7235) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 7235) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 7235) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 7235) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 7235) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 7235) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 7235) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 7235) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 7235) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 7235) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 7235) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 7235) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 7235) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 21 (bases 1 to 7235) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 22 (bases 1 to 7235) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 23 (bases 1 to 7235) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NC_004354). ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..7235 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="X" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..7235 /gene="G9a" /locus_tag="Dmel_CG2995" /gene_synonym="cab65850 G9a Dm; CG2995; dG9a; Dmel\CG2995; EG:BACR37P7.2; EHMT; G9ae" /map="1A1-1A1" /db_xref="FLYBASE:FBgn0040372" /db_xref="GeneID:30971" CDS 873..5846 /gene="G9a" /locus_tag="Dmel_CG2995" /gene_synonym="cab65850 G9a Dm; CG2995; dG9a; Dmel\CG2995; EG:BACR37P7.2; EHMT; G9ae" /EC_number="2.1.1.355" /EC_number="2.1.1.356" /EC_number="2.1.1.367" /EC_number="2.1.1.368" /EC_number="2.1.1.369" /EC_number="2.1.1.371" /note="CG2995 gene product from transcript CG2995-RB; CG2995-PB; G9a-PB; histone methyltransferase; euchromatin histone methyltransferase; dG9a" /codon_start=1 /product="G9a, isoform B" /protein_id="NP_001259088.1" /db_xref="FLYBASE:FBpp0305207" /db_xref="GeneID:30971" /db_xref="FLYBASE:FBgn0040372" /translation="MTDFVELMNSMSSTFNSDCATSTAEGGTLLNLNLAEDKTLKWRN LANNQFASKEKKHKDKEEEERKEARNQEEIEDIKALLADVVDAAAVKLEEEEAQNAEK VEPHTKCEIEEEGRKEMEYDQDVAKQDSEMEKKQNGKATSITVKMESNERAEKHATEI ATTSTERWENESFKTEQQNKKAAEKEEEPILAATQKLEANAEPLTTTRIEVAVASPLV VSSASVKLAADATNQMRAATSAGAATLADKNVQVSPGGTRRSRRTPRPIDTPTSVTDE HVQVENKKFGKSEQYTDCSSHLERFTLDDNTAIVRLQLKSEPDKPSLTALSPEENSAP APKRGRGRARKIRPDAEVETSEVILPCEDSLGEKKPGRKRKLPDEPIDQQQLSDLVVV KTEQEELGDAPLGDVKRMRRSVRLGNRLHADGSPWEEVKTEALHPQPSAELSFAEVTS EILPLAVLDEKTPPKKRGRKAKTPCVKLESETSCGLPFANGNKKTNSSGGCELQLPKR SKRRIKPTPKILENDELRCEFETKHIERMTQWESAAAVDGDFETPTTGGNGSNSSTSR QKSDKSDGSNFEGGPGHPAGTSAIKKRLFSKSQRDIENYGAAMLAKSKLPPCPDVEQF LNDIKASRINANRSPEERKLNKKQQRKLAKQKEKHLKHLGLQKNHRDEPSDNDSSNTD NEFFPTTRVQVGKPSVTLRVRNSVTKELPTTATLKSRRNPVVQAAKLTRRIGARAAGE VTEAARASVPISTPDAEQLHSLDTSIQADVTPIRDLDMRPSTSRVSKFICLCQKPSQY YARNAPDSSYCCAIDHIDDQKIGCCNELSSEVHNLLRPSQRVSYMILCDEHKKRLQSH NCCAGCGIFCTQGKFVLCKQQHFFHPDCAQRFILSTSYEKELGDEEDQGVKFSSPVLV LKCPHCGLDTPERTSTVTMKCQSLPVFLRTQKYKIKPARLTTSSHLTQFGTVENANTP GATARNKGGLSTAVTLSAASSPASKTNGAQRGRAGTSNSNSRHALNSINFAQLIPESV MNVVLRGHVVSASGRVTAEFTPRDMYYAVQNDDLERVAEILAADFNVLTPIREYLNGT CLHLVAHSGTLQMAYLLLCKGASSPDFVNIVDYELRTALMCAVMNEKCDMLNLFLQCG ADVAIKGPDGKTSLHIAAQLGNLEATQLIVDSYRTSRNITSFLSFIDAQDEGGWTAMV WAAELGHTDIVRLASLPQAVFLKLINIFLFISFLLNQDADPNICDNDNNTVLHWSTLH NDGLDTITVLLQSGADCNVQNVEGDTPLHIACRHSVTRMCIALIANGADLMIKNKAEQ LPFDCIPNEESECGRTVGFNMQMRSFRPLGLRTFVVCADASNGREARPIQVVRNELAM SENEDEADSLMWPDFRYVTQCIIQQNSVQIDRRVSQMRICSCLDSCSSDRCQCNGASS QNWYTAESRLNADFNYEDPAVIFECNDVCGCNQLSCKNRVVQNGTRTPLQIVECEDQA KGWGVRALANVPKGTFVGSYTGEILTAMEADRRTDDSYYFDLDNGHCIDANYYGNVTR FFNHSCEPNVLPVRVFYEHQDYRFPKIAFFSCRDIDAGEEICFDYGEKFWRVEHRSCV GCRCLTTTCKYASQSSSTNASPTNATTAPENETGTLSSTNTEKIGHA" misc_feature <1074..>1436 /gene="G9a" /locus_tag="Dmel_CG2995" /gene_synonym="cab65850 G9a Dm; CG2995; dG9a; Dmel\CG2995; EG:BACR37P7.2; EHMT; G9ae" /note="MAEBL; Provisional; Region: PTZ00121" /db_xref="CDD:173412" misc_feature 3228..3671 /gene="G9a" /locus_tag="Dmel_CG2995" /gene_synonym="cab65850 G9a Dm; CG2995; dG9a; Dmel\CG2995; EG:BACR37P7.2; EHMT; G9ae" /note="Zinc-binding domain of euchromatic histone lysine methyltransferases EHMT1 and EHTM2; Region: EHMT_ZBD; cd20905" /db_xref="CDD:411018" misc_feature 4059..4838 /gene="G9a" /locus_tag="Dmel_CG2995" /gene_synonym="cab65850 G9a Dm; CG2995; dG9a; Dmel\CG2995; EG:BACR37P7.2; EHMT; G9ae" /note="Ankyrin repeat [Signal transduction mechanisms]; Region: ANKYR; COG0666" /db_xref="CDD:440430" misc_feature 4134..4232 /gene="G9a" /locus_tag="Dmel_CG2995" /gene_synonym="cab65850 G9a Dm; CG2995; dG9a; Dmel\CG2995; EG:BACR37P7.2; EHMT; G9ae" /note="ANK repeat [structural motif]; Region: ANK repeat" /db_xref="CDD:293786" misc_feature 4242..4331 /gene="G9a" /locus_tag="Dmel_CG2995" /gene_synonym="cab65850 G9a Dm; CG2995; dG9a; Dmel\CG2995; EG:BACR37P7.2; EHMT; G9ae" /note="ANK repeat [structural motif]; Region: ANK repeat" /db_xref="CDD:293786" misc_feature 4335..4460 /gene="G9a" /locus_tag="Dmel_CG2995" /gene_synonym="cab65850 G9a Dm; CG2995; dG9a; Dmel\CG2995; EG:BACR37P7.2; EHMT; G9ae" /note="ANK repeat [structural motif]; Region: ANK repeat" /db_xref="CDD:293786" misc_feature 4467..4619 /gene="G9a" /locus_tag="Dmel_CG2995" /gene_synonym="cab65850 G9a Dm; CG2995; dG9a; Dmel\CG2995; EG:BACR37P7.2; EHMT; G9ae" /note="ANK repeat [structural motif]; Region: ANK repeat" /db_xref="CDD:293786" misc_feature order(4470..4472,4482..4487,4494..4502,4506..4511, 4581..4583,4590..4592,4617..4619,4623..4625,4629..4631, 4641..4646,4653..4661,4668..4673,4683..4685,4692..4694, 4719..4721,4725..4727,4731..4733,4743..4748,4755..4763, 4767..4772,4782..4784,4791..4793,4818..4820) /gene="G9a" /locus_tag="Dmel_CG2995" /gene_synonym="cab65850 G9a Dm; CG2995; dG9a; Dmel\CG2995; EG:BACR37P7.2; EHMT; G9ae" /note="oligomer interface [polypeptide binding]; other site" /db_xref="CDD:293786" misc_feature 4623..4721 /gene="G9a" /locus_tag="Dmel_CG2995" /gene_synonym="cab65850 G9a Dm; CG2995; dG9a; Dmel\CG2995; EG:BACR37P7.2; EHMT; G9ae" /note="ANK repeat [structural motif]; Region: ANK repeat" /db_xref="CDD:293786" misc_feature 4725..4820 /gene="G9a" /locus_tag="Dmel_CG2995" /gene_synonym="cab65850 G9a Dm; CG2995; dG9a; Dmel\CG2995; EG:BACR37P7.2; EHMT; G9ae" /note="ANK repeat [structural motif]; Region: ANK repeat" /db_xref="CDD:293786" misc_feature 5043..5738 /gene="G9a" /locus_tag="Dmel_CG2995" /gene_synonym="cab65850 G9a Dm; CG2995; dG9a; Dmel\CG2995; EG:BACR37P7.2; EHMT; G9ae" /note="SET domain (including pre-SET and post-SET domains) found in euchromatic histone-lysine N-methyltransferase EHMT1, EHMT2 and similar proteins; Region: SET_EHMT; cd10543" /db_xref="CDD:380941" misc_feature order(5355..5363,5412..5414,5433..5435,5442..5447, 5451..5453,5460..5477,5493..5495,5526..5540,5562..5564, 5568..5570,5607..5609,5655..5657,5661..5663,5670..5675, 5700..5714) /gene="G9a" /locus_tag="Dmel_CG2995" /gene_synonym="cab65850 G9a Dm; CG2995; dG9a; Dmel\CG2995; EG:BACR37P7.2; EHMT; G9ae" /note="active site" /db_xref="CDD:380941" misc_feature order(5355..5363,5463..5468,5526..5540,5661..5663, 5673..5675,5700..5714) /gene="G9a" /locus_tag="Dmel_CG2995" /gene_synonym="cab65850 G9a Dm; CG2995; dG9a; Dmel\CG2995; EG:BACR37P7.2; EHMT; G9ae" /note="SAM binding site; other site" /db_xref="CDD:380941" misc_feature order(5433..5435,5442..5447,5451..5453,5460..5462, 5469..5471,5475..5477,5493..5495,5670..5675,5682..5687) /gene="G9a" /locus_tag="Dmel_CG2995" /gene_synonym="cab65850 G9a Dm; CG2995; dG9a; Dmel\CG2995; EG:BACR37P7.2; EHMT; G9ae" /note="polypeptide substrate binding site [polypeptide binding]; other site" /db_xref="CDD:380941" misc_feature order(5544..5546,5706..5708,5712..5714,5727..5729) /gene="G9a" /locus_tag="Dmel_CG2995" /gene_synonym="cab65850 G9a Dm; CG2995; dG9a; Dmel\CG2995; EG:BACR37P7.2; EHMT; G9ae" /note="Zn binding site [ion binding]; other site" /db_xref="CDD:380941" ORIGIN 1 gttgctgttc tttacggata acagttttca gcgcgaagtg cgtgcgtgtg cgtgcgtcaa 61 aaacgcagtt ctgtatgtgt gttcgtgtgc ttttcttata tttttctaaa gtaatgttat 121 tgaactggtt gcctatgtaa agagaaagcc acgaaaacta caagcatttg taaattcgtt 181 gaaaaatttg cagcttacca attccaaaat ctcaaaacag tgactgcaac accaacaaaa 241 acgcagtagc agcgacgtcg gcagagaaac aacaagaaca acaatcttgg cgttgaagcg 301 atgtgagaga gtgtaatatt tgacagcatg tgagctaatc agcaaagcag cgatttctgc 361 aaacattttg agcttcttaa gggcaattaa tgaacgaaaa agtggaaaac tatagtaaat 421 atatagtaag aaatatagtg agaaattttg tatttttacg ttttgttctc tagaaattaa 481 aaaaaagaga ggatacaaaa aatttagctg tgaccaccaa gaaacgcagt cgacttcgct 541 gccggcagaa cgaagaaaaa gaaagagcat aatataaagc agaaaaacca gattttaatg 601 tctaaatttt aaagattaaa tgttttattt tgccttatgt ttgcccattt atactcaaaa 661 atatcggtgt caaaatagtt gcaaattcag aacagcaaag caacaacaaa ggctgctgct 721 tgtacgaccg atgcacaaat cttgtcggga aaaatagggt tctgaaagcg aaattatgtt 781 tttattggct taaagatgga aaattgactc ctgaaatcga aaatcaaaga aactaatacg 841 caaagtaatc aaatagtgac aattaaggca agatgacgga ctttgttgag ctgatgaaca 901 gcatgtccag tacattcaat agcgactgtg ctacttcaac agcggagggt ggtactttgc 961 taaatctgaa cttggcggaa gacaaaaccc tcaagtggcg taatttggcc aataaccagt 1021 tcgctagtaa agaaaagaag cacaaggaca aggaggagga ggagcgcaag gaggcaagga 1081 atcaagagga aatcgaagac atcaaagcac ttttggcaga tgttgtcgat gcggccgctg 1141 tcaagctgga agaagaagaa gcgcagaatg cagaaaaagt cgaaccacat acaaaatgcg 1201 aaatagagga agaaggtagg aaggaaatgg agtacgatca agatgtcgca aaacaagact 1261 ccgaaatgga aaaaaagcag aatggcaaag caacatccat aacagtaaag atggaaagca 1321 acgagcgtgc agagaaacac gcaacggaaa ttgcaacgac gtcgacagag agatgggaaa 1381 acgaaagctt taaaactgag cagcaaaata aaaaagctgc tgagaaagaa gaagaaccca 1441 tactagcagc aacacaaaaa ttggaagcaa atgcagaacc actgacaaca acaagaattg 1501 aggtagcagt agcatctcca cttgttgtta gttctgctag cgttaaactc gctgctgacg 1561 caaccaacca aatgcgagca gcgacgtcgg caggagcagc gacattagct gataaaaatg 1621 tacaagtttc gcccggtgga acgcgacggt ctcgaagaac acccagaccc atagacacgc 1681 ccacttcagt tactgatgaa catgttcagg tggagaataa aaaatttgga aagtcggagc 1741 agtatacgga ttgtagtagc catctggaga ggttcacact ggacgataat actgctattg 1801 tcagactgca gttgaaaagt gaaccggaca aaccgtcatt aactgcatta tctcctgagg 1861 aaaactcggc tcctgctccg aagcgaggaa ggggtcgagc caggaaaata agacccgatg 1921 ccgaggtgga aaccagtgag gttattttac cctgcgagga ttcattaggg gagaagaaac 1981 caggacgcaa aaggaaactc ccggatgaac cgatagatca gcagcaacta agcgaccttg 2041 tcgtggtaaa aacagagcag gaggaattgg gtgacgctcc cttgggagat gttaagagaa 2101 tgcgacgtag cgttcgttta ggcaatcgat tacacgccga tggaagccct tgggaggagg 2161 taaagacaga ggcacttcac ccgcagcctt ctgcagaact ttcctttgcg gaggtcactt 2221 ctgagatctt gccactagct gtcttagatg agaagacccc acccaaaaag cgagggcgga 2281 aggcaaaaac gccctgtgtg aagttagaat ctgaaacatc ctgcgggcta ccgtttgcta 2341 atggcaacaa gaaaacgaat tcctctggtg gatgcgaact tcagctgccc aagcgttcaa 2401 aaagaagaat aaaaccaacg ccaaagatat tagaaaatga cgaactgcgc tgtgagttcg 2461 aaacgaagca cattgagcgt atgacccagt gggagagtgc tgcagcagta gatggggatt 2521 ttgaaacgcc aacaacaggc ggtaatgggt ccaattcctc gacctcaagg caaaagagcg 2581 acaagtccga cgggagcaac ttcgaaggtg gtccaggaca tcctgcaggc acaagtgcca 2641 taaagaaaag actattttca aagtcccagc gggacattga gaactatggc gcagcaatgc 2701 tagccaaaag taagttacct ccgtgtccgg atgtcgaaca atttctaaac gacatcaagg 2761 catctcgaat taacgcgaat cggtcaccag aagaaaggaa attgaacaaa aaacagcaac 2821 gaaaactggc caaacaaaag gaaaagcacc tgaagcattt gggcctgcaa aaaaatcaca 2881 gagatgagcc ctcggataac gacagttcca atacggacaa tgaattcttt cctactacaa 2941 gggtgcaagt gggaaaacca agtgttactt tgagagtaag gaatagtgtt accaaggagc 3001 ttcccaccac agccactttg aaatcacgcc ggaatccagt cgtgcaggca gccaaactca 3061 cgagaaggat aggtgcaaga gccgccggtg aagttactga ggcagcccga gcaagtgtgc 3121 caatttctac acctgatgcg gagcagcttc actcgttgga cacttctatt caagctgatg 3181 ttacgcccat aagagactta gatatgaggc ccagcacctc cagagtgtca aagtttattt 3241 gtctatgtca gaagccttcc cagtattatg ccaggaatgc cccggattca tcatactgct 3301 gtgccatcga tcacatcgac gaccaaaaaa ttggctgctg caacgagctg tcctcagagg 3361 ttcacaatct actcagaccc agccaacgcg ttagctatat gatcctatgc gatgagcaca 3421 aaaagcgcct acaatcacac aactgctgcg caggatgtgg catattttgt acacagggaa 3481 aatttgtgct atgcaagcag cagcacttct ttcatcccga ttgtgcccag cgatttattc 3541 taagcacttc gtacgagaag gaactcggcg atgaggaaga tcagggcgtc aaattcagca 3601 gccctgtctt agtgcttaag tgcccccact gcggattaga tacaccagaa cggacctcca 3661 cggtgaccat gaagtgtcag tccctgcctg tctttctgcg cacgcaaaag tacaagatca 3721 aacccgctag attgacaacc tcttcgcatc taacccaatt tggaacagtt gagaatgcca 3781 ataccccagg agccaccgcc aggaacaagg gaggactatc caccgccgta accttaagcg 3841 cggcatcaag tcctgcctca aaaacaaatg gagcccagag aggcagggcg ggcacctcca 3901 attctaactc caggcatgct cttaattcga tcaactttgc tcaacttata cccgagtccg 3961 taatgaatgt agtgctgcgg ggccacgtgg tttctgctag cggtcgcgtg accgcagagt 4021 ttaccccgcg ggatatgtac tatgcagtcc aaaacgatga cttggagcgt gtagcggaga 4081 ttctggctgc cgacttcaac gtgctgactc ccatacggga gtacttaaat ggcacctgcc 4141 ttcatttggt ggcccactcg ggcacacttc agatggccta tctccttctc tgcaaaggag 4201 caagctcacc ggatttcgtt aatattgtgg attatgaact gcggactgct ttaatgtgtg 4261 ccgtgatgaa cgagaagtgc gacatgctga atctatttct tcaatgtggt gcggatgtgg 4321 ccattaaggg tcccgatggt aagaccagtc tgcatattgc tgcccagtta ggcaacttgg 4381 aagccacaca gttaattgta gacagctatc gaacttctcg aaatattacc agttttttaa 4441 gtttcattga tgcccaggat gaaggcggtt ggacggccat ggtctgggca gcagagctgg 4501 ggcacacgga tatagttagg ttggcttctc tgccccaagc ggttttctta aagctaatta 4561 atatttttct cttcattagc ttcctgctta accaggatgc tgatccaaac atatgcgaca 4621 atgacaacaa tacggtgctg cactggtcta cgctgcacaa tgatggtctg gacacgatta 4681 cagtactgct gcagtcaggg gcggactgca atgtacagaa tgtagagggc gacacgcctt 4741 tgcacattgc ttgccggcat tctgtcaccc gcatgtgcat cgcgttaata gctaatggag 4801 ccgatctaat gattaagaac aaggcggaac aactgccctt tgattgcatt ccgaatgagg 4861 agtctgagtg cggtcgcact gtaggtttta atatgcaaat gcgtagtttc aggcctttgg 4921 gcctccgtac ctttgtggtt tgtgcagatg cgtcgaatgg cagggaggca cgaccaatcc 4981 aggtggttcg caacgaactg gcaatgtctg aaaatgagga tgaggccgat tcgcttatgt 5041 ggccggattt tcgctacgta acacaatgca ttatccagca gaattcagtg cagattgacc 5101 gacgcgtttc tcaaatgcgc atctgctcct gcctggatag ttgcagtagc gatcgctgtc 5161 agtgcaatgg agcctcctcg cagaattggt acacggcaga aagtcggcta aacgccgact 5221 ttaactacga ggatcctgcg gtaatcttcg aatgcaacga cgtctgcggt tgcaaccagc 5281 tgtcctgcaa aaaccgcgtg gtgcagaatg gtacacggac acccctacaa attgtcgagt 5341 gcgaggatca ggcgaagggc tggggagtac gggcgctggc caatgtaccc aaaggcactt 5401 ttgtgggcag ttatacgggt gagattttga ccgcgatgga ggcagatcga cgcaccgatg 5461 acagctacta ctttgacctg gacaacgggc actgcatcga tgccaactat tatggaaatg 5521 taacccggtt ttttaaccac tcgtgtgagc cgaatgtttt gcccgttcgt gttttctacg 5581 agcatcagga ctacagattc cctaagatcg cctttttttc ctgccgtgac atcgatgccg 5641 gagaggaaat atgctttgac tacggagaaa aattctggcg cgtggaacat cgctcctgtg 5701 ttggatgtcg atgcctgaca acaacctgca agtacgcctc ccaatcctca agcacaaatg 5761 cctcgcctac gaatgcaaca acggcaccgg aaaatgaaac gggaacgctg tcgtctacaa 5821 atacggagaa aattggacac gcgtaggcta aaaccaccta aacctgagat gattgcagat 5881 ttcacagtct catccaacaa ataaaatccc cacctaaacc atcagcaacc agatgagccg 5941 ggcatataaa atcgcagcaa ccccaaattc gataacaata tttgtaatat aaacattgaa 6001 tcgttatcga agcccggtcg gctttctttc ttttttgact gccaaatgtt tcgtggttaa 6061 ccacttttta tctattttta cgtatacaaa tagtgtttgt ttattattaa ttttgtttga 6121 tttgtattaa tgttttacgc cttattaata atgtttttat tcttagtacc tgtaaaaaca 6181 aattagttta tactttctgc gcgaaacaaa ctaatgacat aagaagggca tatcaaaatt 6241 gtttcccgat attgtgggtg tgcgtgtttc cggaacgtaa atgttttaaa cttaaaatta 6301 gacttggaca ttaccaggca taaaatagaa ttgtaatgga ggaaagacca tctagtcata 6361 agaatgaagg agacaaagta tttccataga aaagagaaaa aaaatttttt ttaatagaag 6421 tagtcggttt ttttttttaa tttgtatgag ctctggagca tacatatgta aatacgtgat 6481 acgaaaaagt aatacgtttg attttaccgt taaccatgaa aattagaccg tttaaattga 6541 cctgtaatgg gcaactaaat gttactcgca accaaaagta aaggaggaat tatttagcaa 6601 aaaaaaaaaa cattgtctat attatggatt acatgttttg tgcagggtga agtacataca 6661 tacccccaat tgattaccac tctaccaatc ccatcaaatc tgaagtctat cacgtataca 6721 aatttttcag tttgctaagc aagccaagcc acaagtgcct aaaagaaaat tatttcttac 6781 ccggttgccc tttaggataa ccctaatttt actataaagc aatatagttt ttttaggctg 6841 taaatgttaa cgcggggttt gtatgtgtaa ttaactttgt ctgtttaaaa cggcaacatg 6901 taatttaagt cgcaagattt tccgtttcag caacaaagtc ataggtcacc gaaaggcgct 6961 tctttgattt tctgctggca tttttatcca tatttatgta accacgacaa gagtaatgat 7021 gaaaatatat ttatacagat cagtgtccct tggcggtatt aactgttacg gctgacagtt 7081 taagctgtca tcttaatgca tttgtttttt gtttttcttt tgcaataaaa tttgtaagtt 7141 ttacgcataa ttgaaagaat aggtatgcaa ggagtcattt ttcgagtgca gctacgttaa 7201 tgtttaacca taaaatattg aattgattaa attcg