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LOCUS NM_001169247 3196 bp mRNA linear INV 26-DEC-2023 mRNA. ACCESSION NM_001169247 VERSION NM_001169247.1 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 3196) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 3196) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 3196) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 3196) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 3196) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 3196) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 3196) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 3196) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 3196) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 3196) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 3196) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 3196) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 3196) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 3196) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 3196) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 3196) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 3196) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 3196) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 3196) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 3196) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 21 (bases 1 to 3196) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 22 (bases 1 to 3196) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 23 (bases 1 to 3196) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NC_004354). ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..3196 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="X" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..3196 /gene="dlg1" /locus_tag="Dmel_CG1725" /gene_synonym="11; anon-EST:Posey93; anon-WO03040301.258; anon-WO03040301.260; anon-WO03040301.268; CG1725; CG1730; CPD; d. lg.-1; Discs Large; Discs-large; dlg; Dlg; DLG; dlg-1; dlg-A; Dlg-A; DLG-A; Dlg1; DLG1; dlgA; DlgA; dlgS97; DlgS97; Dmel\CG1725; Drodlg; l(1)10Bf; l(1)bwn; l(1)d.lg-1; l(1)d.lg.-1; l(1)discs large; l(1)dlg; l(1)dlg-1; l(1)dlg1; l(1)G0276; l(1)G0342; l(1)G0456; l(1)G19; l(1)l.pr.-2; l(1)L11; l(1)lpr-2; misb; PSD-95; PSD95; SAP97" /note="discs large 1" /map="10B6-10B10" /db_xref="FLYBASE:FBgn0001624" /db_xref="GeneID:32083" CDS 47..3139 /gene="dlg1" /locus_tag="Dmel_CG1725" /gene_synonym="11; anon-EST:Posey93; anon-WO03040301.258; anon-WO03040301.260; anon-WO03040301.268; CG1725; CG1730; CPD; d. lg.-1; Discs Large; Discs-large; dlg; Dlg; DLG; dlg-1; dlg-A; Dlg-A; DLG-A; Dlg1; DLG1; dlgA; DlgA; dlgS97; DlgS97; Dmel\CG1725; Drodlg; l(1)10Bf; l(1)bwn; l(1)d.lg-1; l(1)d.lg.-1; l(1)discs large; l(1)dlg; l(1)dlg-1; l(1)dlg1; l(1)G0276; l(1)G0342; l(1)G0456; l(1)G19; l(1)l.pr.-2; l(1)L11; l(1)lpr-2; misb; PSD-95; PSD95; SAP97" /EC_number="2.7.4.8" /note="CG1725 gene product from transcript CG1725-RM; CG1725-PM; dlg1-PM; discslarge; disc large; lethal(1)discs-large; lethal(2)discs large; disk large; Disc-Large; disclarge; Discs-large; discs large 1; lethal(1)benign wing imaginal disc neoplasm; Discs-large 1; lethal(1)discs large" /codon_start=1 /product="discs large 1, isoform M" /protein_id="NP_001162718.1" /db_xref="FLYBASE:FBpp0290503" /db_xref="GeneID:32083" /db_xref="FLYBASE:FBgn0001624" /translation="MDSDTDSEREKSSDPNEGLLSSDDKTFHDDDEPAEDSSPADDEE EPEEEECLLPQKKAQIRCDQDQPPLVVLVQPSAEAIEVRQEIDDTNPVAVAAKASDMD GDSQLEVMEHQMETVTEPDPEPPKCPTSLRDSVRESVECFYSAQDLLEYGHMLSSTSM VRTPDVESGYFEKSESDASRDEWEGPSSSSSGAARCRLLSGISGLSVSSSSRHSAEGL RMELSRFRTMIETLERESLEKSQSELQLKAKSKAKPKPKQRSHVQDAAGESGSEQGSE RGFWSTIFGQAGLAISQDEEERIADIQKAHRALELLEDYHARLSEPQDRALRIAIERV IRIFKSRLFQALLDIQEFYELTLLDDSKSIQQKTAETLQIATKWEKDGQAVKIADNQR MRIESDTENAKEPTVEQQQKQQQAQQRSSRSPQQQNPQQQQGSKSRSGSQTVNGDDSW LYEDIQLERGNSGLGFSIAGGTDNPHIGTDTSIYITKLISGGAAAADGRLSINDIIVS VNDVSVVDVPHASAVDALKKAGNVVKLHVKRKRGTATTPAAGSAAGDARDSAASGPKV IEIDLVKGGKGLGFSIAGGIGNQHIPGDNGIYVTKLMDGGAAQVDGRLSIGDKLIAVR TNGSEKNLENVTHELAVATLKSITDKVTLIIGKTQHLTTSASGGGGGGLSSGQQLSQS QSQLATSQSQSQVHQQQHATPMVNSQSTEPGSRYASTNVLAAVPPGTPRAVSTEDITR EPRTITIQKGPQGLGFNIVGGEDGQGIYVSFILAGGPADLGSELKRGDQLLSVNNVNL THATHEEAAQALKTSGGVVTLLAQYRPEEYNRFEARIQELKQQAALGAGGSGTLLRTT QKRSLYVRALFDYDPNRDDGLPSRGLPFKHGDILHVTNASDDEWWQARRVLGDNEDEQ IGIVPSKRRWERKMRARDRSVKFQGHAAANNNLDKQSTLDRKKKNFTFSRKFPFMKSR DEKNEDGSDQEPFMLCYTQDDANAEGGEIIYRVELPDMEQITLIYLENNDADYRKSSI " misc_feature 953..1129 /gene="dlg1" /locus_tag="Dmel_CG1725" /gene_synonym="11; anon-EST:Posey93; anon-WO03040301.258; anon-WO03040301.260; anon-WO03040301.268; CG1725; CG1730; CPD; d. lg.-1; Discs Large; Discs-large; dlg; Dlg; DLG; dlg-1; dlg-A; Dlg-A; DLG-A; Dlg1; DLG1; dlgA; DlgA; dlgS97; DlgS97; Dmel\CG1725; Drodlg; l(1)10Bf; l(1)bwn; l(1)d.lg-1; l(1)d.lg.-1; l(1)discs large; l(1)dlg; l(1)dlg-1; l(1)dlg1; l(1)G0276; l(1)G0342; l(1)G0456; l(1)G19; l(1)l.pr.-2; l(1)L11; l(1)lpr-2; misb; PSD-95; PSD95; SAP97" /note="Region: L27_1; pfam09058" /db_xref="CDD:462665" misc_feature 1400..1666 /gene="dlg1" /locus_tag="Dmel_CG1725" /gene_synonym="11; anon-EST:Posey93; anon-WO03040301.258; anon-WO03040301.260; anon-WO03040301.268; CG1725; CG1730; CPD; d. lg.-1; Discs Large; Discs-large; dlg; Dlg; DLG; dlg-1; dlg-A; Dlg-A; DLG-A; Dlg1; DLG1; dlgA; DlgA; dlgS97; DlgS97; Dmel\CG1725; Drodlg; l(1)10Bf; l(1)bwn; l(1)d.lg-1; l(1)d.lg.-1; l(1)discs large; l(1)dlg; l(1)dlg-1; l(1)dlg1; l(1)G0276; l(1)G0342; l(1)G0456; l(1)G19; l(1)l.pr.-2; l(1)L11; l(1)lpr-2; misb; PSD-95; PSD95; SAP97" /note="PDZ domain 1 of human discs large homolog 1 (Dlg1), Dlg2, and Dlg4, Drosophila disc large (Dlg), and related domains; Region: PDZ1_Dlg1-2-4-like; cd06723" /db_xref="CDD:467206" misc_feature order(1433..1453,1502..1504,1511..1513,1601..1603, 1613..1615,1622..1627) /gene="dlg1" /locus_tag="Dmel_CG1725" /gene_synonym="11; anon-EST:Posey93; anon-WO03040301.258; anon-WO03040301.260; anon-WO03040301.268; CG1725; CG1730; CPD; d. lg.-1; Discs Large; Discs-large; dlg; Dlg; DLG; dlg-1; dlg-A; Dlg-A; DLG-A; Dlg1; DLG1; dlgA; DlgA; dlgS97; DlgS97; Dmel\CG1725; Drodlg; l(1)10Bf; l(1)bwn; l(1)d.lg-1; l(1)d.lg.-1; l(1)discs large; l(1)dlg; l(1)dlg-1; l(1)dlg1; l(1)G0276; l(1)G0342; l(1)G0456; l(1)G19; l(1)l.pr.-2; l(1)L11; l(1)lpr-2; misb; PSD-95; PSD95; SAP97" /note="peptide binding site [polypeptide binding]; other site" /db_xref="CDD:467206" misc_feature 1748..2014 /gene="dlg1" /locus_tag="Dmel_CG1725" /gene_synonym="11; anon-EST:Posey93; anon-WO03040301.258; anon-WO03040301.260; anon-WO03040301.268; CG1725; CG1730; CPD; d. lg.-1; Discs Large; Discs-large; dlg; Dlg; DLG; dlg-1; dlg-A; Dlg-A; DLG-A; Dlg1; DLG1; dlgA; DlgA; dlgS97; DlgS97; Dmel\CG1725; Drodlg; l(1)10Bf; l(1)bwn; l(1)d.lg-1; l(1)d.lg.-1; l(1)discs large; l(1)dlg; l(1)dlg-1; l(1)dlg1; l(1)G0276; l(1)G0342; l(1)G0456; l(1)G19; l(1)l.pr.-2; l(1)L11; l(1)lpr-2; misb; PSD-95; PSD95; SAP97" /note="PDZ domain 2 of human discs large homolog 1 (Dlg1), Dlg2, and Dlg4, Drosophila disc large (Dlg), and related domains; Region: PDZ2_Dlg1-2-4-like; cd06724" /db_xref="CDD:467207" misc_feature order(1775..1795,1844..1846,1853..1855,1955..1957, 1967..1969,1976..1981) /gene="dlg1" /locus_tag="Dmel_CG1725" /gene_synonym="11; anon-EST:Posey93; anon-WO03040301.258; anon-WO03040301.260; anon-WO03040301.268; CG1725; CG1730; CPD; d. lg.-1; Discs Large; Discs-large; dlg; Dlg; DLG; dlg-1; dlg-A; Dlg-A; DLG-A; Dlg1; DLG1; dlgA; DlgA; dlgS97; DlgS97; Dmel\CG1725; Drodlg; l(1)10Bf; l(1)bwn; l(1)d.lg-1; l(1)d.lg.-1; l(1)discs large; l(1)dlg; l(1)dlg-1; l(1)dlg1; l(1)G0276; l(1)G0342; l(1)G0456; l(1)G19; l(1)l.pr.-2; l(1)L11; l(1)lpr-2; misb; PSD-95; PSD95; SAP97" /note="peptide binding site [polypeptide binding]; other site" /db_xref="CDD:467207" misc_feature 2267..2539 /gene="dlg1" /locus_tag="Dmel_CG1725" /gene_synonym="11; anon-EST:Posey93; anon-WO03040301.258; anon-WO03040301.260; anon-WO03040301.268; CG1725; CG1730; CPD; d. lg.-1; Discs Large; Discs-large; dlg; Dlg; DLG; dlg-1; dlg-A; Dlg-A; DLG-A; Dlg1; DLG1; dlgA; DlgA; dlgS97; DlgS97; Dmel\CG1725; Drodlg; l(1)10Bf; l(1)bwn; l(1)d.lg-1; l(1)d.lg.-1; l(1)discs large; l(1)dlg; l(1)dlg-1; l(1)dlg1; l(1)G0276; l(1)G0342; l(1)G0456; l(1)G19; l(1)l.pr.-2; l(1)L11; l(1)lpr-2; misb; PSD-95; PSD95; SAP97" /note="PDZ domain 3 of human discs large homolog 1 (Dlg1), Dlg2, and Dlg4, Drosophila disc large (Dlg), and related domains; Region: PDZ3_Dlg1-2-4-like; cd06795" /db_xref="CDD:467257" misc_feature order(2303..2323,2354..2356,2363..2365,2453..2455, 2465..2467,2474..2479) /gene="dlg1" /locus_tag="Dmel_CG1725" /gene_synonym="11; anon-EST:Posey93; anon-WO03040301.258; anon-WO03040301.260; anon-WO03040301.268; CG1725; CG1730; CPD; d. lg.-1; Discs Large; Discs-large; dlg; Dlg; DLG; dlg-1; dlg-A; Dlg-A; DLG-A; Dlg1; DLG1; dlgA; DlgA; dlgS97; DlgS97; Dmel\CG1725; Drodlg; l(1)10Bf; l(1)bwn; l(1)d.lg-1; l(1)d.lg.-1; l(1)discs large; l(1)dlg; l(1)dlg-1; l(1)dlg1; l(1)G0276; l(1)G0342; l(1)G0456; l(1)G19; l(1)l.pr.-2; l(1)L11; l(1)lpr-2; misb; PSD-95; PSD95; SAP97" /note="peptide binding site [polypeptide binding]; other site" /db_xref="CDD:467257" misc_feature 2630..2812 /gene="dlg1" /locus_tag="Dmel_CG1725" /gene_synonym="11; anon-EST:Posey93; anon-WO03040301.258; anon-WO03040301.260; anon-WO03040301.268; CG1725; CG1730; CPD; d. lg.-1; Discs Large; Discs-large; dlg; Dlg; DLG; dlg-1; dlg-A; Dlg-A; DLG-A; Dlg1; DLG1; dlgA; DlgA; dlgS97; DlgS97; Dmel\CG1725; Drodlg; l(1)10Bf; l(1)bwn; l(1)d.lg-1; l(1)d.lg.-1; l(1)discs large; l(1)dlg; l(1)dlg-1; l(1)dlg1; l(1)G0276; l(1)G0342; l(1)G0456; l(1)G19; l(1)l.pr.-2; l(1)L11; l(1)lpr-2; misb; PSD-95; PSD95; SAP97" /note="Src Homology 3 domain of Disks large homolog proteins; Region: SH3_DLG-like; cd11861" /db_xref="CDD:212795" misc_feature order(2636..2638,2702..2707) /gene="dlg1" /locus_tag="Dmel_CG1725" /gene_synonym="11; anon-EST:Posey93; anon-WO03040301.258; anon-WO03040301.260; anon-WO03040301.268; CG1725; CG1730; CPD; d. lg.-1; Discs Large; Discs-large; dlg; Dlg; DLG; dlg-1; dlg-A; Dlg-A; DLG-A; Dlg1; DLG1; dlgA; DlgA; dlgS97; DlgS97; Dmel\CG1725; Drodlg; l(1)10Bf; l(1)bwn; l(1)d.lg-1; l(1)d.lg.-1; l(1)discs large; l(1)dlg; l(1)dlg-1; l(1)dlg1; l(1)G0276; l(1)G0342; l(1)G0456; l(1)G19; l(1)l.pr.-2; l(1)L11; l(1)lpr-2; misb; PSD-95; PSD95; SAP97" /note="GuK domain interface [polypeptide binding]; other site" /db_xref="CDD:212795" misc_feature order(2645..2647,2651..2653,2660..2662,2687..2689, 2741..2746,2801..2803,2807..2812) /gene="dlg1" /locus_tag="Dmel_CG1725" /gene_synonym="11; anon-EST:Posey93; anon-WO03040301.258; anon-WO03040301.260; anon-WO03040301.268; CG1725; CG1730; CPD; d. lg.-1; Discs Large; Discs-large; dlg; Dlg; DLG; dlg-1; dlg-A; Dlg-A; DLG-A; Dlg1; DLG1; dlgA; DlgA; dlgS97; DlgS97; Dmel\CG1725; Drodlg; l(1)10Bf; l(1)bwn; l(1)d.lg-1; l(1)d.lg.-1; l(1)discs large; l(1)dlg; l(1)dlg-1; l(1)dlg1; l(1)G0276; l(1)G0342; l(1)G0456; l(1)G19; l(1)l.pr.-2; l(1)L11; l(1)lpr-2; misb; PSD-95; PSD95; SAP97" /note="peptide ligand binding site [polypeptide binding]; other site" /db_xref="CDD:212795" ORIGIN 1 cggcacttgg gcgcgaagag aggtgtcttc ttggctggtc ctggtaatgg attcggatac 61 ggactcggag cgggagaaga gcagcgatcc caacgaggga ctgctcagta gcgatgacaa 121 gacattccac gacgatgatg aaccggcgga ggattcctct ccggcggacg atgaggagga 181 gcccgaggag gaggagtgcc tgctgccgca gaagaaggca cagattcgct gcgaccaaga 241 ccagccacct ttggtggtct tggtacagcc gtcggcggaa gccatagaag tgcgccaaga 301 aatcgatgat accaatccgg tggcagtagc tgccaaagct agcgatatgg atggggattc 361 gcaactggag gtgatggaac accaaatgga gaccgtaacc gaaccggatc ccgagcctcc 421 gaagtgtcca acatccctgc gcgatagtgt ccgcgagtcc gttgaatgct tctattccgc 481 ccaggatctt ctcgagtacg gacacatgct gtcctccact tcgatggtcc gaacaccgga 541 tgtggagtct ggctactttg agaagtccga gagcgatgct tcgcgcgacg agtgggaggg 601 tccgtcgtcg tcatcctcgg gcgcagcccg ttgtcgcctt ctctccggca tttccggact 661 ctccgtctct tcgtcgagtc gccacagtgc cgagggtttg cgcatggaac tgagccgatt 721 tcgcaccatg atcgagactc tcgagcggga aagtctcgag aaatcgcaat cggagctgca 781 gttgaaggcc aagagcaagg cgaagccaaa gcccaagcag agatcccacg tacaggatgc 841 ggctggggaa agtggttcgg aacagggttc cgagaggggc ttctggtcaa cgatcttcgg 901 ccaggcgggt ctggcgatca gtcaggatga ggaggagcgc attgcggaca tacagaaagc 961 tcatcgggct ctcgagctgc tcgaggacta ccacgcgaga ctttcggagc cgcaggatcg 1021 ggcgctgcgt attgcaatcg aacgcgttat acgcatattt aaatctcgct tgtttcaagc 1081 gctgttagat atacaagaat tctatgaatt gacattattg gatgactcga agagcataca 1141 acaaaagaca gcggagacct tgcaaattgc aaccaaatgg gaaaaggatg gccaggcagt 1201 caaaatagct gataatcagc gcatgcgcat cgaatcggac acggaaaatg ccaaggagcc 1261 aactgtcgag cagcagcaaa agcagcagca agcgcagcag cgcagttccc gctccccgca 1321 gcagcagaat ccgcagcagc agcagggatc caaatcgagg agcgggtccc agactgtgaa 1381 tggcgatgat agctggttat acgaggacat tcagctggag cgcggcaact ccggattggg 1441 cttttccatt gccggcggta cggataatcc gcacatcggc accgacacct ccatctacat 1501 caccaagctc atttccggtg gagcagctgc cgccgatgga cgtctgagca tcaacgatat 1561 catcgtatcg gtgaacgatg tgtccgtggt ggatgtgcca catgcctccg ccgtggatgc 1621 cctcaagaag gcgggcaatg ttgttaagct gcatgtgaag cgaaaacgtg gaacggccac 1681 caccccggca gcgggatcgg cggcaggaga tgctcgggat agtgcggcca gcggaccgaa 1741 ggtcatcgaa atcgatctgg tcaagggcgg caagggactg ggcttctcaa ttgccggcgg 1801 cattggcaac cagcacatcc ccggcgacaa tggcatctat gtgaccaagt tgatggacgg 1861 cggagcagcg caggtggacg gacgtctctc catcggagat aagctgattg cagtgcgcac 1921 caacgggagc gagaagaacc tggagaacgt aacgcacgaa ctggcggtgg ccacgttgaa 1981 atcgatcacc gacaaggtga cgctgatcat tggaaagaca cagcatctga ccaccagtgc 2041 gtccggcggc ggaggaggag gcctttcatc cggacaacaa ttgtcgcagt cccaatcgca 2101 gttggccacc agccagagcc aaagtcaggt gcatcagcag cagcatgcga cgccgatggt 2161 caattcgcag tcgacagagc ccgggtcgcg atacgcctct acaaatgtcc tagccgccgt 2221 tccaccagga actccacgcg ctgtcagcac cgaggatata accagagaac cgcgcaccat 2281 caccatccag aagggaccgc agggcctggg cttcaatatc gttggcggcg aggatggcca 2341 gggtatctat gtgtccttca tcctggccgg cggcccagcg gatctcgggt cggagttgaa 2401 gcgtggcgac cagctgctca gcgtgaacaa tgtcaatctc acgcacgcca cccacgaaga 2461 ggcagcccag gcgctcaaga cttctggcgg tgtggtgacc ctgttggcgc agtaccgccc 2521 agaggagtac aatcgcttcg aggcacgcat tcaagagttg aaacaacagg ctgccctcgg 2581 tgccggcgga tcgggaacgc tgctgcgcac cacgcaaaag cgatcgctgt atgtgcgcgc 2641 cctgtttgac tacgatccga atcgggatga tggattgccc tcgcgaggat tgccctttaa 2701 gcacggcgat atcctgcacg tgaccaatgc ctccgacgat gaatggtggc aggcacgacg 2761 agttctcggc gacaacgagg acgagcaaat cggtattgta ccatcgaaaa ggcgttggga 2821 gcgcaaaatg cgagctaggg accgcagcgt taagttccag ggacatgcgg cagctaataa 2881 taatctggat aagcaatcga cattggatcg aaagaaaaag aatttcacat tctcgcgcaa 2941 atttccgttt atgaagagtc gcgatgagaa gaatgaagat ggcagcgacc aagagccctt 3001 tatgctttgc tacacacaag acgatgccaa tgctgaagga ggcgagatta tctacagggt 3061 ggagttaccc gatatggagc agataactct gatctacttg gagaataatg atgctgacta 3121 tcgtaagtcg agcatctgaa caaccaacaa tcacaaaaaa tataaattaa aacaaccaca 3181 agaatcaaca gcaaac