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LOCUS NM_001169200 6060 bp mRNA linear INV 26-DEC-2023 variant G (Ptp4E), mRNA. ACCESSION NM_001169200 VERSION NM_001169200.2 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 6060) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 6060) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 6060) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 6060) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 6060) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 6060) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 6060) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 6060) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 6060) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 6060) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 6060) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 6060) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 6060) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 6060) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 6060) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 6060) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 6060) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 6060) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 6060) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 6060) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 21 (bases 1 to 6060) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 22 (bases 1 to 6060) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 23 (bases 1 to 6060) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NC_004354). On Jul 15, 2014 this sequence version replaced NM_001169200.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..6060 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="X" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..6060 /gene="Ptp4E" /locus_tag="Dmel_CG6899" /gene_synonym="4E; CG6899; CT21187; Dmel\CG6899; DPTP4E; ptp4E; PtP4E; PTP4E; R-PTP 4E" /note="Protein tyrosine phosphatase 4E" /map="4D7-4D7" /db_xref="FLYBASE:FBgn0004368" /db_xref="GeneID:31425" CDS 299..5146 /gene="Ptp4E" /locus_tag="Dmel_CG6899" /gene_synonym="4E; CG6899; CT21187; Dmel\CG6899; DPTP4E; ptp4E; PtP4E; PTP4E; R-PTP 4E" /EC_number="3.1.3.-" /EC_number="3.1.3.48" /note="CG6899 gene product from transcript CG6899-RG; CG6899-PG; Ptp4E-PG" /codon_start=1 /product="protein tyrosine phosphatase 4E, isoform G" /protein_id="NP_001162671.2" /db_xref="FLYBASE:FBpp0310132" /db_xref="GeneID:31425" /db_xref="FLYBASE:FBgn0004368" /translation="MDCATRKQQQLRAHHQQQQIQIQTHGRKRQQLQKQRHNHHHYYQ NSQQQQKHFVWLVVGILTIFLAQHANAADLVINVPNASSNANAFYRIDYSPPFGFPEP NTTIPASDIGKDIKFSRALPGTEYNFWLYYTNSTHREQLTWTVNITTAPDPPANLSVQ LRSSKSAFITWRPPGSGRYSGFRIRVLGLTDLPFERSYSLEGNETLQLSAKELTPGGS YQVQAYSVYQGKESVAYTSRNFTTKPNTPGKFIVWFRNETTLLVLWQPPFPAGIYTHY RVSITPDDAIQSVLYVEREGEPPGPAQAAFKGLVPGREYNISVQTVSEDETSSVPTTA RYLTVPERVLNVTFDEAYTTSSSFRVRWEPPRTYSEFDAYQVMLSTSRRIFNVPRAAN GDSVYFDYPDILEPGRTYEVVVKTIADNVNSWPASGEVTLRPRPVRSLGGFLDDRSNA LHISWEPAETGRQDSYRISYHEQTNASEVPAPFPVAAESQITTNLTEYTLDSLLAGRR YLIAVQALSKGVASNASDITRYTRPAAPLIQELRSIDQGLMLSWRSDVNSRQDRYEVH YQRNGTREERTMATNETSLTIHYLHPGSGYEVKVHAISHGVRSEPHSYFQAVFPKPPQ NLTLQTVHTNLVVLHWQAPEGSDFSEYVVRYRTDASPWQRISGLHENEARIKDMHYGE RYLVQVNTVSFGVESPHPLELNVTMPPQPVSNVVPLVDSRNLTLEWPRPDGHVDFYTL KWWPTDEEDRVEFKNVTQLEDLSSPSVRIPIEDLSPGRQYRFEVQASSNGIRSGTTHL STRTMPLIQSDVFIANAGHEQGQDETITLSYTPTPADSTRFDIYRFSMGDPTIKDKEK LANDTERKLSFSGLTPGKLYNVTVWTVSGGVASLPVQRLYRLHPLPISDLKAIQVAAR EITLHWTAPAGEYTDFELQYLSADEEAPQLLQNVTKNTEITLQGLRPYHNYTFTVVVR SGSIQGTDFADVSVSTLMRSSAPISASYQTLTAPPGKVDYFQPSDVQPGEVTFEWSLE PAEQHGPIDYFRITCQNADDAADVSSYEFPVNATQGKIDGLVPGNHYIFRIQAKSALG YGAEREHIQTMPILAPPVPEPSVTPLEVSRTSSTIEISFRQGYFSNAHGMVRSYTIII AEDVGKNASGLEMPSWQDVQAYTVWLPYQAIEPYNPFLTSNGSRKSSLEAEHFTIGTA NCDKHQAGYCNGPLRAGTTYRIKIRAFTDEDKFTDTVYSSPITTERSDTVIVAATVSA VLLVAMVLVVVYCQHRCQLIRRASKLARMQDELAALPEGYITPNRPVHVKDFSEHYRI MSADSDFRFSEEFEELKHVGRDQACSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDD DGSDYINANYMPGHNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCFEKGRE KCDQYWPVDRVAMFYGDIKVQLIIDTHYHDWSISEFMVSRNCESRIMRHFHFTTWPDF GVPEPPQSLVRFVRAFRDVIGTDMRPIIVHCSAGVGRSGTFIALDRILQHIHKSDYVD IFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVLEGKEHLLADSLELHANDGYEDDEGI AETGI" misc_feature <578..>1300 /gene="Ptp4E" /locus_tag="Dmel_CG6899" /gene_synonym="4E; CG6899; CT21187; Dmel\CG6899; DPTP4E; ptp4E; PtP4E; PTP4E; R-PTP 4E" /note="Fibronectin type 3 domain [General function prediction only]; Region: FN3; COG3401" /db_xref="CDD:442628" misc_feature order(1028..1030,1229..1231,1274..1276) /gene="Ptp4E" /locus_tag="Dmel_CG6899" /gene_synonym="4E; CG6899; CT21187; Dmel\CG6899; DPTP4E; ptp4E; PtP4E; PTP4E; R-PTP 4E" /note="Interdomain contacts [active]" /db_xref="CDD:238020" misc_feature 1037..1282 /gene="Ptp4E" /locus_tag="Dmel_CG6899" /gene_synonym="4E; CG6899; CT21187; Dmel\CG6899; DPTP4E; ptp4E; PtP4E; PTP4E; R-PTP 4E" /note="Fibronectin type III domain; Region: fn3; pfam00041" /db_xref="CDD:394996" misc_feature 1253..>2545 /gene="Ptp4E" /locus_tag="Dmel_CG6899" /gene_synonym="4E; CG6899; CT21187; Dmel\CG6899; DPTP4E; ptp4E; PtP4E; PTP4E; R-PTP 4E" /note="Fibronectin type 3 domain [General function prediction only]; Region: FN3; COG3401" /db_xref="CDD:442628" misc_feature order(1277..1282,1286..1291) /gene="Ptp4E" /locus_tag="Dmel_CG6899" /gene_synonym="4E; CG6899; CT21187; Dmel\CG6899; DPTP4E; ptp4E; PtP4E; PTP4E; R-PTP 4E" /note="Cytokine receptor motif [active]" /db_xref="CDD:238020" misc_feature 2420..2686 /gene="Ptp4E" /locus_tag="Dmel_CG6899" /gene_synonym="4E; CG6899; CT21187; Dmel\CG6899; DPTP4E; ptp4E; PtP4E; PTP4E; R-PTP 4E" /note="Fibronectin type III domain; Region: fn3; pfam00041" /db_xref="CDD:394996" misc_feature order(2423..2425,2624..2626,2669..2671) /gene="Ptp4E" /locus_tag="Dmel_CG6899" /gene_synonym="4E; CG6899; CT21187; Dmel\CG6899; DPTP4E; ptp4E; PtP4E; PTP4E; R-PTP 4E" /note="Interdomain contacts [active]" /db_xref="CDD:238020" misc_feature order(2996..2998,3179..3181,3224..3226) /gene="Ptp4E" /locus_tag="Dmel_CG6899" /gene_synonym="4E; CG6899; CT21187; Dmel\CG6899; DPTP4E; ptp4E; PtP4E; PTP4E; R-PTP 4E" /note="Interdomain contacts [active]" /db_xref="CDD:238020" misc_feature 3002..3232 /gene="Ptp4E" /locus_tag="Dmel_CG6899" /gene_synonym="4E; CG6899; CT21187; Dmel\CG6899; DPTP4E; ptp4E; PtP4E; PTP4E; R-PTP 4E" /note="Fibronectin type III domain; Region: fn3; pfam00041" /db_xref="CDD:394996" misc_feature order(3227..3232,3236..3241) /gene="Ptp4E" /locus_tag="Dmel_CG6899" /gene_synonym="4E; CG6899; CT21187; Dmel\CG6899; DPTP4E; ptp4E; PtP4E; PTP4E; R-PTP 4E" /note="Cytokine receptor motif [active]" /db_xref="CDD:238020" misc_feature order(3317..3319,3515..3517,3560..3562) /gene="Ptp4E" /locus_tag="Dmel_CG6899" /gene_synonym="4E; CG6899; CT21187; Dmel\CG6899; DPTP4E; ptp4E; PtP4E; PTP4E; R-PTP 4E" /note="Interdomain contacts [active]" /db_xref="CDD:238020" misc_feature 3335..3574 /gene="Ptp4E" /locus_tag="Dmel_CG6899" /gene_synonym="4E; CG6899; CT21187; Dmel\CG6899; DPTP4E; ptp4E; PtP4E; PTP4E; R-PTP 4E" /note="Fibronectin type III domain; Region: fn3; pfam00041" /db_xref="CDD:394996" misc_feature 3677..4039 /gene="Ptp4E" /locus_tag="Dmel_CG6899" /gene_synonym="4E; CG6899; CT21187; Dmel\CG6899; DPTP4E; ptp4E; PtP4E; PTP4E; R-PTP 4E" /note="TM proximal of protein tyrosine phosphatase, receptor type J; Region: PTP_tm; pfam18861" /db_xref="CDD:465889" misc_feature 4370..5035 /gene="Ptp4E" /locus_tag="Dmel_CG6899" /gene_synonym="4E; CG6899; CT21187; Dmel\CG6899; DPTP4E; ptp4E; PtP4E; PTP4E; R-PTP 4E" /note="catalytic domain of R3 subfamily receptor-type tyrosine-protein phosphatases and similar proteins; Region: R3-PTPc; cd14548" /db_xref="CDD:350396" ORIGIN 1 tattcattcg ttaagcgacg gtcgtccaaa aaggcagaaa atgtggaaat tcattgatga 61 acagtggtga aaaagagtgc aatacaagtg caatattaat taagtaatag aggaaacgta 121 atatgcgtgt gcaatacaaa caaatgacca tgtaacggcc aacagaaatg tatatgcaat 181 acaaacgtac atacatgtgt aaaacaataa gcgcaaaaca ccgcccatcc ccgcttgaaa 241 agtaaaacca gcaatctgcg aaaccttcga ccatcattgg gttttactgt acttgaaaat 301 ggactgtgcc acgcgaaaac aacaacaatt acgggcacat catcagcagc aacaaataca 361 aatacaaaca catggacgaa agcggcagca attacaaaaa caacgccaca accaccacca 421 ctactaccaa aattcacaac aacaacaaaa acatttcgtg tggcttgttg ttggcatttt 481 gacaattttt ttggctcagc acgcaaatgc cgctgatcta gtgataaatg taccaaatgc 541 gagcagcaac gccaacgcct tctacagaat cgactacagt ccgccctttg gcttcccgga 601 gccgaacacc acgattccgg ccagtgatat tggcaaggac atcaagttct cgagggctct 661 gccgggcacg gagtacaact tttggctgta ctacacaaac tccacgcatc gggagcagct 721 tacgtggacg gtgaacataa cgacagctcc cgatccgccg gccaatctta gtgtgcagct 781 gcggtccagc aagagtgcgt ttataacgtg gcgaccgcct ggatcgggtc gctactcggg 841 atttcggatc cgtgtgctgg gcctcacgga tctgccattt gagcgcagct actcgctgga 901 aggcaacgaa acgttgcagt tatcggccaa ggaactgaca cccgggggca gctaccaggt 961 tcaggcgtac tctgtctacc agggcaagga atcggtggcc tacacaagtc gcaactttac 1021 cacaaagccc aacacgcccg ggaagttcat tgtgtggttc cggaatgaga cgaccctcct 1081 ggtgctgtgg cagccaccgt ttccggctgg aatctatacc cactacaggg tatccataac 1141 gccggacgac gccatccaga gtgtactgta tgtggaacgg gagggtgaac cgccgggacc 1201 ggcacaggcg gcattcaaag gtctcgttcc cggcagagag tacaatatct cggtgcagac 1261 ggtttccgag gatgaaacgt cgtcggtccc aacgacagcc agatatttaa ccgtaccgga 1321 gcgcgtgcta aatgtcacct tcgacgaggc ctataccaca tcgagttcct ttcgcgtaag 1381 atgggagccg ccgcgaacct acagcgaatt cgatgcctac caggtgatgc tctccacgtc 1441 gcgtaggata tttaatgtgc cacgcgcagc gaatggcgat tcggtgtatt tcgactatcc 1501 ggatattttg gagccaggtc gcacgtacga agtggtggtc aagacaattg cggacaatgt 1561 gaattcgtgg ccagccagcg gagaggtcac tctgcgtcca cggccagttc gcagtctggg 1621 cggattcctc gacgatcgca gcaatgctct gcacatatcg tgggaaccgg cggaaacggg 1681 acgacaggac tcgtatcgaa ttagctacca tgagcagacg aatgccagcg aggtgccggc 1741 accgtttccg gttgccgctg aatcccaaat caccacgaat cttacggagt acacactgga 1801 ctcgctgctg gcaggacgac gctatctgat cgccgtgcag gccctgtcca agggtgtggc 1861 ctccaatgcc agcgacataa cgcgctacac acgtccggcg gcgccactta ttcaggaatt 1921 gaggagcatc gatcagggtc tcatgctcag ctggcgtagt gatgtgaact ctcgccagga 1981 tcgctatgag gtgcactacc agcgcaatgg aacgcgcgag gagcgcacaa tggccaccaa 2041 tgagacaagt ctgacgatac actacctgca cccaggatcc ggttatgagg tgaaggtgca 2101 cgccattagc cacggagtgc gaagcgaacc gcactcctat ttccaagcag tttttcccaa 2161 accgcctcag aatctcaccc tgcagacagt gcatacgaat ctagtggtgc ttcattggca 2221 ggcgccggag ggcagcgact ttagtgaata tgtagtgcga taccgcacgg atgcctcgcc 2281 ctggcagcgg atatccggat tgcacgagaa cgaggcgaga atcaaggaca tgcattatgg 2341 cgaacggtat ctggtgcagg tgaacaccgt gagctttggc gtcgagagtc cccatccgct 2401 cgagctgaat gtgacgatgc caccgcaacc ggtgtcgaat gtggtgccat tggtggattc 2461 gcgtaatctc accctggaat ggccgagacc cgatggtcat gtggatttct acacactcaa 2521 gtggtggccc accgatgagg aggatcgtgt ggagttcaag aatgttacgc agttggagga 2581 tttaagctct cccagcgttc ggatacccat tgaagatttg tcgccaggtc gccagtatcg 2641 tttcgaggtt caagccagtt ccaatggcat tcgttcgggg actacccatc tgtccacccg 2701 caccatgcca ctgattcaat ccgatgtgtt catcgccaat gcggggcacg aacagggtca 2761 ggatgagacc attaccctta gttacacacc cacgccggcg gacagtactc gcttcgatat 2821 ctatcgcttt tcgatgggcg atccgacgat caaggacaag gaaaaactgg ccaacgatac 2881 ggaacgcaag ctgagctttt cgggactgac gcctggcaag ctgtataacg tgaccgtgtg 2941 gacagtgagt ggcggagtgg ccagtttgcc ggttcaacgg ctatatcgcc tgcatccgct 3001 gcccattagt gatttgaagg ccatccaggt ggctgctcgt gagataacgc tgcattggac 3061 agcacctgct ggcgaatata ctgattttga actgcagtac ctaagtgcag acgaggaggc 3121 accacaactg cttcagaatg tgaccaagaa tacagagatt acgctgcagg gcttgcgtcc 3181 gtatcacaat tacacattca ccgtggtggt gcgatcgggc tccatccagg gcacagattt 3241 cgccgatgtt tccgtcagca ccctgatgcg cagcagtgct cccatctcgg ccagttacca 3301 aacgctgacc gctccgccgg gaaaagtcga ttacttccag cccagtgatg tgcagcctgg 3361 tgaggttacc ttcgagtgga gtctggaacc cgccgaacag catggaccca tcgattactt 3421 ccgcattaca tgccaaaatg ctgacgatgc agcggatgta tcaagctacg aattcccggt 3481 gaatgctacc cagggaaaga ttgatggttt ggtacccggc aatcattaca tattccgaat 3541 acaagccaag tcggctttgg gctacggtgc cgaacgggag cacatccaaa caatgcccat 3601 actagcacct ccggttccgg agccaagtgt aacaccactg gaagtgagca ggaccagtag 3661 caccatcgag attagtttcc gtcagggtta cttctccaac gctcatggca tggtaagatc 3721 ctatacgata atcatagccg aggatgtggg caaaaatgcc tccggactgg agatgcccag 3781 ctggcaggat gtgcaggcat ataccgtgtg gctgccttat caagccatag agccatacaa 3841 tccattcctg accagcaatg gcagcagaaa gagcagcctg gaggcagagc attttacgat 3901 aggaacggcg aactgcgata aacatcaggc gggctactgc aatggtccgc tgcgggctgg 3961 aaccacctat aggattaaga ttcgtgcctt tacggacgag gacaagttca cggacacggt 4021 gtacagttca ccgataacca ccgaacgcag tgataccgtc atagtggcgg ctaccgtttc 4081 ggctgtgtta ctggtggcaa tggtgcttgt ggtggtgtac tgtcagcacc gctgccaact 4141 gattcgtcgc gcctccaagt tggcacgcat gcaggacgag ctggccgccc tgcccgaggg 4201 ctatatcacg cccaaccgac ctgttcatgt gaaagacttc tccgagcact acaggatcat 4261 gtcggccgat tcggactttc gtttcagcga ggagttcgaa gagctgaagc atgtgggccg 4321 cgatcaggcc tgcagctttg ccaatctgcc ctgcaatcgg cccaagaacc gatttaccaa 4381 tatcctgccc tacgaccatt cccgttttaa gctccagcca gtggacgacg acgatggttc 4441 ggattatatt aatgcgaact acatgccggg acacaattcg ccgcgcgagt ttatcgtcac 4501 ccagggaccg ttgcactcga cgcgcgagga attctggcgg atgtgctggg agagcaactc 4561 cagggcgatt gtcatgctga cgcgctgctt tgagaagggt cgcgagaaat gcgatcagta 4621 ctggcccgtg gatcgggtgg ccatgttcta cggggacatc aaggtgcagt tgattatcga 4681 cacgcactac cacgactgga gcatatcaga gtttatggtc tcaaggaact gcgaatcgcg 4741 tataatgcgt cactttcact tcaccacatg gccggacttt ggggttccag agccgccgca 4801 gtcgctggtt cgctttgtgc gcgccttccg cgatgtcatc ggcacagata tgcgtcccat 4861 catcgtccat tgcagcgctg gagtgggcag atcgggcacg tttatagccc tggatcgcat 4921 cctgcagcac attcacaagt cagactacgt ggacattttt ggcatcgtgt ttgccatgcg 4981 aaaggagcgc gtttttatgg tgcagacgga acagcagtat gtgtgcatcc atcagtgtct 5041 gctggcggtg ctggagggca aggagcacct gctggccgat tcgctcgagc tgcacgccaa 5101 cgatggctac gaagatgacg aaggcatagc tgagacggga atctgaggat gcttgctgcg 5161 ggaacatcta catatgatat atagtaccta tagttatttt tttttttttt acatatacta 5221 tacgtaaaat ctgcctgtga tgtgctggat gtgatttgtc tacgaagtgg cactcggagt 5281 tgctgtcaaa tgagttgagt ttgttgccca tattctgcgg aggatcgtcg gcagattcat 5341 ccgtgggata atggatgcgc tttttggcct gtgccatgtg tgcgagtacg ccgtaccgcc 5401 tgtttgccat agagctaagc tagctagccc gcttatttaa tgtaatgccg ccaaactcta 5461 gaccaaacca acaagagcgt aaacttaagc ttcaggttta acaatctgct acctattttt 5521 gtatctgtac ctacctgtat ccctgtacct actgtataac tacctaaaca aaaaaaaaaa 5581 aaaaaactat ttacatatta ccctttgctc tgtcgtgttg tgtatagatt tgtacatttg 5641 ttaccactta gtgtgcgcgt cgatcgatat tatgaccata ctatgtttac cattaccact 5701 atgactatta ctctaaacga ttgtgtatta ttttattata tagtttatat agcctagtta 5761 cgttttatcg atagacttta gaccacgatt agtcagcgaa atgttggctc taactgcatg 5821 cagctttcca tttgcccttt ccgttggcca tcaagtctcg aaataaccaa gcgattccat 5881 cggatctgtc cgaagcagca ttagtaccgt accgtaccgt acagtacagt acagtacagt 5941 acactgcagt taaagttatt agcatttatt ttactatatt ttattttatg atattgtatt 6001 gtattgtatt gtattttttt tagatgtgca tctacacaag atcaataaat ttatattgag