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LOCUS NM_001103457 3593 bp mRNA linear INV 26-DEC-2023 ACCESSION NM_001103457 VERSION NM_001103457.4 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 3593) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 3593) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 3593) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 3593) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 3593) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 3593) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 3593) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 3593) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 3593) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 3593) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 3593) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 3593) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 3593) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 3593) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 3593) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 3593) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 3593) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 3593) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 3593) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 3593) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 21 (bases 1 to 3593) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 22 (bases 1 to 3593) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 23 (bases 1 to 3593) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NC_004354). On Jan 16, 2013 this sequence version replaced NM_001103457.3. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..3593 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="X" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..3593 /gene="Sp1" /locus_tag="Dmel_CG1343" /gene_synonym="CG1343; D-Sp1; D-Sp8; D.Sp1; Dmel\CG1343; dSp1; sp1; SP1" /map="9A1-9A1" /db_xref="FLYBASE:FBgn0020378" /db_xref="GeneID:31913" CDS 917..3064 /gene="Sp1" /locus_tag="Dmel_CG1343" /gene_synonym="CG1343; D-Sp1; D-Sp8; D.Sp1; Dmel\CG1343; dSp1; sp1; SP1" /note="CG1343 gene product from transcript CG1343-RD; CG1343-PD; Sp1-PD" /codon_start=1 /product="Sp1, isoform D" /protein_id="NP_001096927.2" /db_xref="FLYBASE:FBpp0271862" /db_xref="GeneID:31913" /db_xref="FLYBASE:FBgn0020378" /translation="MLTDMTPTAGQLYGSQIPAMGMNISNIATHLQKPQVNPDHPSLR GTPLAMLAAQCNKLSNKSPPPLADAAVGKGFHPWKKSPNSPAAGSSGSSGGGGGGGGS SAGQHSPCAISAASSSSSSGSSGGQSSRSLSSSASTMVNITASRPLASSCAAVGGGST GSSSSASGSQSSSTASAVAAAYGGDLYFPNTSTSNMDNHHMHQGLLGKVEAGAAAFGG VYSRHPYDWPFNAVTHKEAASVNSGWWDMHSAAGSWLDMGGAGMHSTMANYASENYSS ALSHSLLGSGQHLLQDTYKSMLPGQGVGVGVGVGMGGFSLPHSSPSAAAAAAATAAAA AGGSPQGGSPSTPSPRSQRRYAGRATCDCPNCQEAERLGPAGVHLRKKNIHSCHIPGC GKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRFACPVC NKRFMRSDHLAKHVKTHNGTANHQANGHNGGLKKGSSESCSDSEEAANQSGESNGLGG VGSGPQTGGAGGGGGGSSSGNGAGTLAVSGSVTTGAGAGSGTGSSNSNSNSGGSSGSV SGSVSGSGSHPGTPTSLHAHSANGTSSSLLGGGLHLATPHQMVAAGGSPVMLHQQQQQ QQHQQQQQQQQQQQHQQQQQQQHQQQQQQHQQQQQQHHQQQQQHHHQQFGQQQHPHAH HLHHHAHHAHHLATGGSPGLDPSSLVDIKPPMV" misc_feature 1064..2074 /gene="Sp1" /locus_tag="Dmel_CG1343" /gene_synonym="CG1343; D-Sp1; D-Sp8; D.Sp1; Dmel\CG1343; dSp1; sp1; SP1" /note="N-terminal domain of invertebrate transcription factor Specificity Proteins (SP) similar to SP6, SP8 and SP9; Region: SP6-9-like_N; cd22547" /db_xref="CDD:411694" misc_feature 2084..2143 /gene="Sp1" /locus_tag="Dmel_CG1343" /gene_synonym="CG1343; D-Sp1; D-Sp8; D.Sp1; Dmel\CG1343; dSp1; sp1; SP1" /note="C2H2 Zn finger [structural motif]; Region: C2H2 Zn finger" /db_xref="CDD:275368" misc_feature order(2096..2098,2102..2104,2108..2110,2114..2119, 2126..2131,2138..2140,2186..2188,2192..2194,2204..2209, 2216..2221,2228..2230,2270..2272,2276..2278,2282..2284, 2288..2293,2300..2305,2312..2314) /gene="Sp1" /locus_tag="Dmel_CG1343" /gene_synonym="CG1343; D-Sp1; D-Sp8; D.Sp1; Dmel\CG1343; dSp1; sp1; SP1" /note="putative nucleic acid binding site [nucleotide binding]; other site" /db_xref="CDD:275368" misc_feature 2117..2200 /gene="Sp1" /locus_tag="Dmel_CG1343" /gene_synonym="CG1343; D-Sp1; D-Sp8; D.Sp1; Dmel\CG1343; dSp1; sp1; SP1" /note="Zinc-finger double domain; Region: zf-H2C2_2; pfam13465" /db_xref="CDD:463886" misc_feature 2165..2233 /gene="Sp1" /locus_tag="Dmel_CG1343" /gene_synonym="CG1343; D-Sp1; D-Sp8; D.Sp1; Dmel\CG1343; dSp1; sp1; SP1" /note="C2H2 Zn finger [structural motif]; Region: C2H2 Zn finger" /db_xref="CDD:275368" misc_feature 2207..2278 /gene="Sp1" /locus_tag="Dmel_CG1343" /gene_synonym="CG1343; D-Sp1; D-Sp8; D.Sp1; Dmel\CG1343; dSp1; sp1; SP1" /note="Zinc-finger double domain; Region: zf-H2C2_2; pfam13465" /db_xref="CDD:463886" misc_feature 2249..2317 /gene="Sp1" /locus_tag="Dmel_CG1343" /gene_synonym="CG1343; D-Sp1; D-Sp8; D.Sp1; Dmel\CG1343; dSp1; sp1; SP1" /note="Zinc finger, C2H2 type; Region: zf-C2H2; pfam00096" /db_xref="CDD:395048" misc_feature 2255..2317 /gene="Sp1" /locus_tag="Dmel_CG1343" /gene_synonym="CG1343; D-Sp1; D-Sp8; D.Sp1; Dmel\CG1343; dSp1; sp1; SP1" /note="C2H2 Zn finger [structural motif]; Region: C2H2 Zn finger" /db_xref="CDD:275368" ORIGIN 1 aacagttgca agcctttgaa cgatcagcga cgacggcgtt acttttggcg cggatacagc 61 agcgacactt ttttttcgtt ggcaggcgcc tcctgtcacc aaacaaacaa ataaataaac 121 aaataaacat aaaaacaaac aagcaaataa ataaacaata aaccaacaag caaacaaaca 181 aacataaaca agccaacaag cagccaagct aaacaaaaca actgtgtgca tttttggttc 241 gagtttcctt taatttccat cgcttatatt tcattttttt tttgcctgtg ttccttagaa 301 aagaagtcta taaagaataa aaaaaataaa aaaaaaatta agcccatata taggcacaaa 361 atcccagtga caataagagc agtcaaacat tgcaactctc agcagcaaac atcagccgac 421 ggccgagtga agaaaagtgc aacgccgacg gactcgagaa aagatacaga tacagatacg 481 gattatacat atctgggcta ttagctgggc cataatctgc tctcaagcga tttagcccac 541 tttgcttttt ttctgagtgc gtgtgtgctt gtgctgtgct gtgctgtgct gtgctgtgct 601 tgccaatcca tttgtccatg tcctttacat cttttttccc ttactctcca agatcagtga 661 gcctggcctg caacaatagt cgcaacaaag aaaaaagtag ttgagttgag caagaagaaa 721 agaatagaaa atcgaaccct aaacccaagt ggccgcaaaa caaagcagaa gcaaaacaga 781 cagcatcatt gtgcgcctca aattgacatc agcagcagca gcagcagccg cagcagcaac 841 gacaactgcc actgccactg cagcagcagc aacatcagca gcagcaggag acgcagcagg 901 aacatccaca gcaaccatgt taacggacat gacaccgacc gccggtcagc tctacggatc 961 ccagattccg gccatgggca tgaacatcag caatatcgcc acacacttgc agaagccaca 1021 agttaatccg gatcatccca gcttgagagg aactccgctg gccatgctgg ccgcccagtg 1081 caacaagcta tccaacaaat ccccaccccc gctggccgac gccgctgtgg gcaagggctt 1141 ccatccgtgg aagaagagtc ccaattcgcc ggcagccgga tccagtggct cctccggcgg 1201 tggtggcggc ggcggtggca gtagcgccgg ccagcactcg ccctgcgcca tctcagcggc 1261 cagctcgtcc agctcgagcg gatcaagcgg aggacagtcc tccaggagcc tctcatccag 1321 cgccagcacc atggttaaca tcacagctag tcgccccctg gcctcctcct gtgcggcggt 1381 gggcgggggc tccaccggct cctcctcctc cgcctctgga tcacagtcat cctcgacggc 1441 atctgcggtg gcagcggcct acggcggtga tttgtacttt ccgaacacat ccacctcgaa 1501 catggacaac catcacatgc atcagggtct cctgggtaaa gtggaggcgg gtgcggctgc 1561 ctttggcggt gtctattcgc gtcatccgta cgattggccc ttcaatgcgg ttacccacaa 1621 ggaggcggcc agcgtgaatt ccggctggtg ggacatgcac agtgccgccg gatcctggct 1681 ggatatgggt ggtgcgggca tgcactcaac aatggccaat tatgcgagtg agaactatag 1741 ctccgcattg agtcattcgc tgttgggatc gggacaacat ttgctgcagg acacctacaa 1801 gagcatgttg cccggccagg gagttggcgt tggtgtgggc gttggcatgg gtggcttctc 1861 cctgcctcac agttcaccat cggcggcagc agcagctgcg gccacagcgg cagcggcggc 1921 gggtggctcc ccccagggtg gttcaccatc gacaccatca cccagatccc agaggcgtta 1981 tgccggacgg gccacatgcg attgcccgaa ttgccaggag gcggaacgcc tgggtcccgc 2041 tggcgttcat ctgcgcaaaa agaacatcca ttcgtgtcac atacctggct gtggcaaggt 2101 gtatggaaag acgtcacatc tgaaggctca cctgcggtgg cacaccggcg agcgtccctt 2161 tgtgtgcaac tggctgttct gcggcaagcg tttcacacgc tccgacgagc tgcaacggca 2221 tttgaggacg cacaccggcg agaagcgctt tgcatgcccc gtgtgcaata agcgctttat 2281 gcgcagcgac catttggcca agcacgtgaa gacgcacaat ggcacggcca atcaccaggc 2341 caatggccac aatggtgggc tgaagaaggg ctcctcggag tcgtgtagcg actcggagga 2401 ggccgccaac cagtcgggcg agtccaacgg gctgggcggc gtgggcagtg gcccacagac 2461 gggcggggcc ggtggcggcg ggggtggctc tagttcgggc aatggtgctg gtacgttagc 2521 ggtatcggga tcggtgacca ccggagcggg agctggatcc ggtacgggta gctccaattc 2581 caattccaat tccggtggct caagcggttc cgttagcggt tccgtatccg gttctggcag 2641 ccatcccggc accccgacct cgctgcacgc gcacagcgcc aatggcacgt ccagcagcct 2701 gctgggcggc ggtctgcacc tggccacgcc gcaccagatg gtcgccgcgg gcggttcgcc 2761 ggtgatgctt caccagcagc agcagcagca gcaacatcag cagcaacagc agcaacagca 2821 gcagcagcag catcaacagc agcaacagca gcaacatcaa cagcagcagc agcaacatca 2881 gcagcagcag cagcaacacc accagcaaca gcagcagcat catcaccagc aatttggcca 2941 gcagcagcat ccccatgccc atcacctgca ccaccatgcc caccacgcgc accacctggc 3001 caccggcggc tcacccggtc tggatcccag ctccctcgtg gatataaagc caccgatggt 3061 ttgaggatcg ctgggaccct tcctgttcac caactaaaac agcgcaaggg ttccacacca 3121 tagatactac gtaccacgta ttacgtatat aaataaattt atataaaatc gatatcattt 3181 tgatttgaag ctatcttgcg gttgtacata tagccagcag atgtctgtaa atagatttga 3241 gaaagaaacg cccgctctat gtgtctattg cgctaatccc agcactaaac taaaactgaa 3301 agtaaaatat tacaaaatat aaatataaat ataaatatat tgcttatagc ctatttgtag 3361 actaagccat tttctagact atctagttat caacactgaa tgatgaagga gagcgatatt 3421 tttttttttg tatttttttt actagctcta tggatatgta atttttttca taggttctaa 3481 gcattatata cgacattaac caagagacaa gcttcgagca ccacaaaaac aaaatcccta 3541 taaaaacaag cgataagaac cattatgcaa ttctaaacga agacacctaa aac