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LOCUS NM_001031893 4309 bp mRNA linear INV 26-DEC-2023 mRNA. ACCESSION NM_001031893 VERSION NM_001031893.2 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 4309) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 4309) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 4309) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 4309) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 4309) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 4309) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 4309) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 4309) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 4309) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 4309) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 4309) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 4309) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 4309) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 4309) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 4309) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 4309) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 4309) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 4309) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 4309) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 4309) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 21 (bases 1 to 4309) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 22 (bases 1 to 4309) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 23 (bases 1 to 4309) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NC_004354). On Dec 17, 2009 this sequence version replaced NM_001031893.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..4309 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="X" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..4309 /gene="Sxl" /locus_tag="Dmel_CG43770" /old_locus_tag="Dmel_CG14425" /old_locus_tag="Dmel_CG18350" /gene_synonym="CG14425; CG18350; CG33070; CG43770; Dm-Sxl; Dmel\CG43770; DmSxl; dSXL; Fl; fs(1)K1274; fs(1)M106; l(1)6Fa; melSxl; Mex156; ORF2; Su(da); Sx1; sxl; SxL; SXL; Sxl-1 Sxl-2; Sxl-Pe; SxlPe; SxlPm" /note="Sex lethal" /map="6F3-6F5" /db_xref="FLYBASE:FBgn0264270" /db_xref="GeneID:3772180" CDS 426..572 /gene="Sxl" /locus_tag="Dmel_CG43770" /old_locus_tag="Dmel_CG14425" /old_locus_tag="Dmel_CG18350" /gene_synonym="CG14425; CG18350; CG33070; CG43770; Dm-Sxl; Dmel\CG43770; DmSxl; dSXL; Fl; fs(1)K1274; fs(1)M106; l(1)6Fa; melSxl; Mex156; ORF2; Su(da); Sx1; sxl; SxL; SXL; Sxl-1 Sxl-2; Sxl-Pe; SxlPe; SxlPm" /note="CG43770 gene product from transcript CG43770-RM; CG43770-PM; Sxl-PM; Sex-kethal; sex-lethal; Sex lethal; female lethal; sexlethal" /codon_start=1 /product="Sex lethal, isoform M" /protein_id="NP_001027064.1" /db_xref="FLYBASE:FBpp0303698" /db_xref="GeneID:3772180" /db_xref="FLYBASE:FBgn0264270" /translation="MYGNNNPGSNNNNGGYPPYGYNNKSRHIFFHSPERSSHHYHRKA KDTH" ORIGIN 1 acactgcttt gttgttgccg aagaaggaaa gtcgcgcagt gaattttttt ctgcgcgcct 61 acaagaacag ctataataag cacacactta aaaaaaaccc cataggactt aagagaggaa 121 agcacagtga gcgtgcacac atgtaaaaag agaaagagag caacagcaat tttagtacaa 181 cacaagaaag ttgaacagag gcagaagaga agtaacagga aaacaataac aacgacagca 241 gcaggccagc tgagagcgct gagcgccaaa acaattgaag agatcgattg aatctcgatc 301 atcgttctta acctcaagtc aactgcaact cacctcatca tccttttcct gtaaaaccga 361 aactcacctt cgatcgaggg tgtaactttt gttgattcga aaaacacact cccaactctc 421 aggatatgta cggcaacaat aatccgggta gtaacaataa taatggtggt tatcccccat 481 atggctacaa caacaagtcg agacatattt tttttcacag cccagaaaga agcagccacc 541 attatcaccg aaaagcgaaa gacactcact gactcttaag atagtatgta gtttttattt 601 gcacgggggg gcaaacgcgc cagctccgcc ccccatggtc tcctcgccaa cgaaacgcaa 661 tgtttttgaa tcgaggacac ctccaaagcc cttggtgggc gtggatttgg gatgtcccat 721 tctctgccat ccggaatgga tacagaattt tcatttccaa gttcatcgtc gcgtcgtggt 781 tacaatgatt tccccggctg cggcggcagc ggcggaaatg gtgggagtgc caacaattta 841 gggggcggca acatgtgcca cctgccgccg atggccagca acaactcgct gaataatctc 901 tgcggattgt cgctgggcag cggtggtagt gatgatctca tgaacgatcc tcgggcaagc 961 aacaccaacc tgattgtcaa ctacttgccc caggacatga ccgatcgcga gctgtacgcc 1021 ctattcagag ccattggacc catcaacacg tgcagaatca tgcgagacta taagactggc 1081 tacagttttg gttatgcttt cgtggacttc acatcggaaa tggactcgca gcgtgctatt 1141 aaagtgctga atggcatcac agtgcgcaac aagcggctta aggtttccta tgcacgtccc 1201 ggcggagaat cgatcaagga caccaatctg tatgtgacca atctgccgcg taccataacc 1261 gacgatcagc tggacacgat cttcggcaag tacggttcca ttgtgcagaa gaacatcttg 1321 cgtgacaagc tcacaggtcg tcctcgtggt gtggcctttg ttcggtacaa caagcgtgag 1381 gaggcccagg aggccatttc ggcgctgaac aacgtaatac ccgagggcgg atcacagccg 1441 ctgtccgtcc ggttggctga ggagcatggc aaggcgaagg cggcccactt tatgtcgcag 1501 atgggcgtgg ttccagcaaa tgtaccaccg ccgccaccac aaccgccagc acatatggcc 1561 gccgcattca acatgatgca cagagacgga gctatggaaa aattacgctc attattcgat 1621 gctatatgcg atgctatctt tggtctcgat agcgaaaact ttgccgattt gcttgacgga 1681 ttgtaccgta ggaagtacca ttatccttac ttataattga caccgcaaca gcagcagcaa 1741 ctactacaac atcagcagca ggcgttgggc ttcaccagta gctccaataa tagtattggc 1801 aatggtaatg gcaacgacaa caacatgcta ctttaccacc agcaatacca tcaacaacaa 1861 acacaacaac aacgcctggg caatgttgct gctcacaata taagtccaaa tggaagcaat 1921 aataacatta acacgtcgaa caccaataac attaacttca atacaatacg tcagaatgga 1981 gttgctgctc ttcactatct tcaggaacaa ttgcaattgc aacaaccgca ggatcaacaa 2041 tcacagcaac agcagccatt gactatgcca tcttcgccgc cgtttcaaca acaatcacgc 2101 caatcacacc acaatggcag cagtagcact ctgggcaatc agttgcttgc cataagcaac 2161 aacaatagct tcaataataa ttccaatcaa tccaatagtt ttactggcaa ttacagcaac 2221 ggtagcgctt ttaccagtaa cggtgccatt agcggtagca actttcccaa caatcccaca 2281 agcagtggga acttcaccaa caactcaaca aacagcaacc ccacaaacag tggacacttt 2341 gccagtaatt tggctggcag cagcaacttt accaaccatc tttctggcag caacaattac 2401 accaacagca acggaaattt caccagtaat gcagctagca gtagcaactt ctccaacaat 2461 gcagctagca gcaccaatta cagcaagaac tgcagcagcg gcgtcgttgg aaacagcgat 2521 cccgacagtt gtagcagaaa acacaccacc aacactaata atcaccacac ttcgccgcag 2581 cacgacttca gttttaatat gtcaacgact gaacaagaac tgcatcagca gacactcaag 2641 ttgcagcagc tgcatctgaa caacagcttc aacaacacca cagcagctgc aacaacttca 2701 gcggctgcat caacttccac ttcaacaacg gcaacggcat catccacaaa ctccgcaaat 2761 gtcggatttt tatggcgtac ataaccagag agttgagaag cgtatgatga aggcaatctt 2821 caaattaaag attatatata aaaagcttat atatataaaa ctatgaatac cttatattga 2881 tcatcgtagt atcagcattc atcgaaacca tatacaacaa ctgaaacttt tatgttctca 2941 aaccacaaga attaatttac tacttttttt ttttttgtat gttcctcact ttaacccata 3001 tgttgtagtt ggttttttgt gctttttttt tgggaggaat cctgttgtaa ctagctctaa 3061 ggcaagacac gtatatgtat acaaatcata aataattata tatatataca tatatatata 3121 tatatatata aagaatgaaa aatcgacgaa gatttttttt ttgcttaaac ttagagaaaa 3181 aacctatgag aaatacattt ttttgtcaca tatttataac gtataatcat aacgaaaacg 3241 acaaaatata ttatacaaac acacatatat atctatacta tataacatac ttataggcgt 3301 gatgaaataa gctccgattg tttttttttt ttctgtctga aactgatttt tttggcgcga 3361 actatgccgc aacaatgtac acggtcatcg tgtatgttta tagctgaagt taatccagat 3421 atatgaatat atatattatt ttttttcata atttataaat ccaatttttt tgtctatatt 3481 atacgtaacg aaacggctaa aatgactgga catgctcaag ttttcaggct gtttattcat 3541 aacatataaa acgaaaacat acaacttagc tagcagtatg cttgagtagg cgaaggagaa 3601 agagaatcag acaaaattac aatacaaacc caattttttt catagctata atgaatatgt 3661 tttttttttt ttaataagta taaaaacttt tcttgaaatc catttttttt tattagttta 3721 attaacgaaa caacttgagc atgtaacagc aagaaaaaca aaagtaacat tcaaaaagcg 3781 actaacaaag aaacgtgata aatagcccgt caaaacgaaa atcagaggaa accgaatggg 3841 aaaggtaaaa gaaaaaaata gagacacaat cgaaagtaac gaaagagaaa cacgtcaaat 3901 cacaggagtg acttggtttg attgcctaaa aaacgcatgg ataacgtttt aacttttaat 3961 ttgcctaaca cacttttcga aattctaaat tggccagtca ctccttctgc aggcaaaaaa 4021 tattttttcg gtgtaggtac ataagtaaat gaaacagaaa cattattttg ttactacaat 4081 atatgcgatg atcctttttt gcaaaattct atcaatactt ttatgaatat acttttataa 4141 tcaaacaaaa aattgtgaaa aaattttaat ttgttaaaaa acagaagaaa aaatcagaat 4201 ttcaatttta ttttattatt ttattaccat ggcttaaaac aaatcataca aggaaataag 4261 aaaaaccatt atttaaggaa acttaataaa cattttcgac acaaaccac